bio-maf 0.1.0

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  1. data/.document +5 -0
  2. data/.simplecov +1 -0
  3. data/.travis.yml +16 -0
  4. data/.yardopts +3 -0
  5. data/DEVELOPMENT.md +40 -0
  6. data/Gemfile +23 -0
  7. data/LICENSE.txt +20 -0
  8. data/README.md +209 -0
  9. data/Rakefile +76 -0
  10. data/VERSION +1 -0
  11. data/benchmarks/dispatch_bench +53 -0
  12. data/benchmarks/iter_bench +44 -0
  13. data/benchmarks/read_bench +40 -0
  14. data/benchmarks/sort_bench +33 -0
  15. data/benchmarks/split_bench +33 -0
  16. data/bin/maf_count +82 -0
  17. data/bin/maf_dump_blocks +27 -0
  18. data/bin/maf_extract_ranges_count +44 -0
  19. data/bin/maf_index +88 -0
  20. data/bin/maf_parse_bench +94 -0
  21. data/bin/maf_to_fasta +68 -0
  22. data/bin/maf_write +84 -0
  23. data/bin/random_ranges +35 -0
  24. data/features/maf-indexing.feature +31 -0
  25. data/features/maf-output.feature +29 -0
  26. data/features/maf-parsing.feature +44 -0
  27. data/features/maf-querying.feature +75 -0
  28. data/features/maf-to-fasta.feature +50 -0
  29. data/features/step_definitions/convert_steps.rb +45 -0
  30. data/features/step_definitions/index_steps.rb +20 -0
  31. data/features/step_definitions/output_steps.rb +27 -0
  32. data/features/step_definitions/parse_steps.rb +63 -0
  33. data/features/step_definitions/query_steps.rb +31 -0
  34. data/features/step_definitions/ucsc_bin_steps.rb +14 -0
  35. data/features/support/env.rb +16 -0
  36. data/features/ucsc-bins.feature +24 -0
  37. data/lib/bio/maf/index.rb +620 -0
  38. data/lib/bio/maf/parser.rb +888 -0
  39. data/lib/bio/maf/struct.rb +63 -0
  40. data/lib/bio/maf/writer.rb +63 -0
  41. data/lib/bio/maf.rb +4 -0
  42. data/lib/bio/ucsc/genomic-interval-bin.rb +13 -0
  43. data/lib/bio/ucsc/ucsc_bin.rb +117 -0
  44. data/lib/bio/ucsc.rb +2 -0
  45. data/lib/bio-maf/maf.rb +3 -0
  46. data/lib/bio-maf.rb +12 -0
  47. data/man/.gitignore +1 -0
  48. data/man/maf_index.1 +105 -0
  49. data/man/maf_index.1.markdown +97 -0
  50. data/man/maf_index.1.ronn +83 -0
  51. data/man/maf_to_fasta.1 +53 -0
  52. data/man/maf_to_fasta.1.ronn +51 -0
  53. data/spec/bio/maf/index_spec.rb +363 -0
  54. data/spec/bio/maf/parser_spec.rb +354 -0
  55. data/spec/bio/maf/struct_spec.rb +75 -0
  56. data/spec/spec_helper.rb +14 -0
  57. data/test/data/big-block.maf +15999 -0
  58. data/test/data/chr22_ieq.maf +11 -0
  59. data/test/data/chrY-1block.maf +6 -0
  60. data/test/data/empty +0 -0
  61. data/test/data/empty.db +0 -0
  62. data/test/data/mm8_chr7_tiny.kct +0 -0
  63. data/test/data/mm8_chr7_tiny.maf +76 -0
  64. data/test/data/mm8_mod_a.maf +7 -0
  65. data/test/data/mm8_single.maf +13 -0
  66. data/test/data/mm8_subset_a.maf +23 -0
  67. data/test/data/t1-bad1.maf +15 -0
  68. data/test/data/t1.fasta +12 -0
  69. data/test/data/t1.maf +15 -0
  70. data/test/data/t1a.maf +17 -0
  71. data/test/helper.rb +18 -0
  72. data/test/test_bio-maf.rb +7 -0
  73. data/travis-ci/install_kc +13 -0
  74. data/travis-ci/install_kc_java +13 -0
  75. data/travis-ci/report_errors +4 -0
  76. metadata +181 -0
@@ -0,0 +1,11 @@
1
+ ##maf version=1 scoring=autoMZ.v1
2
+ a score=13668.000000
3
+ s hg19.chr22 16054189 54 + 51304566 TCTGTGAAACCCACAGTAATGGGGCTGACATCCTCTGCCCTATGCAAGAGAGGT
4
+ s ponAbe2.chrUn 13354616 54 + 72422247 TCTTTCAAACCCACAGTAATGGGGCTGACATCCTCTACCATATGCAAGAGAGGT
5
+ q ponAbe2.chrUn 855489998999999899968899889893997969799999879999999989
6
+ i ponAbe2.chrUn C 0 C 0
7
+ s panTro2.chrUn 7684562 54 + 58616431 TCTGTGAAACCCACAGTAATGGGGCTGACATCCTCTGCCCTATGCAAGAGAGAT
8
+ q panTro2.chrUn 999999999999999999999999999999999999999999999999999999
9
+ i panTro2.chrUn C 0 C 0
10
+ e turTru1.scaffold_109008 25049 1601 + 50103 I
11
+
@@ -0,0 +1,6 @@
1
+ ##maf version=1 scoring=autoMZ.v1
2
+ a score=4443.000000
3
+ s hg19.chrY 10501 107 + 59373566 GGACAGCCCGGAAAATGAGCTCCTCATCTCTAACCCAGTTCCCCTGTGGGGATTTAGGGGACCAGGGACAGCCCGTTGCATGAGCCCCTGGACTCTAACCCAGTTCC
4
+ s tarSyr1.scaffold_53149 1869 107 + 12002 GGACAGCCCCACAGATGATCTCCTGTTCTGTAAACCAGTTCCCCTGGAGGGACTGAAGGAACCTGGGAGAGGCCCGCAGAGGGTCTCCTGGTTTGTAGGCCAGTTCC
5
+ q tarSyr1.scaffold_53149 99999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999999
6
+ i tarSyr1.scaffold_53149 N 0 N 0
data/test/data/empty ADDED
File without changes
Binary file
Binary file
@@ -0,0 +1,76 @@
1
+ ##maf version=1
2
+ a score=10542.0
3
+ s mm8.chr7 80082334 34 + 145134094 GGGCTGAGGGC--AGGGATGG---AGGGCGGTCC--------------CAGCA-
4
+ s rn4.chr1 136011785 34 + 267910886 GGGCTGAGGGC--AGGGACGG---AGGGCGGTCC--------------CAGCA-
5
+ s oryCun1.scaffold_199771 14021 43 - 75077 -----ATGGGC--AAGCGTGG---AGGGGAACCTCTCCTCCCCTCCGACAAAG-
6
+ s hg18.chr15 88557580 27 + 100338915 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
7
+ s panTro2.chr15 87959837 27 + 100063422 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
8
+ s rheMac2.chr7 69864714 28 + 169801366 -------GGGC--AAGTATGGA--AGGGAAGCCC--------------CAGAA-
9
+ s canFam2.chr3 56030570 39 + 94715083 AGGTTTAGGGCAGAGGGATGAAGGAGGAGAATCC--------------CTATG-
10
+ s dasNov1.scaffold_106893 7435 34 + 9831 GGAACGAGGGC--ATGTGTGG---AGGGGGCTGC--------------CCACA-
11
+ s loxAfr1.scaffold_8298 30264 38 + 78952 ATGATGAGGGG--AAGCGTGGAGGAGGGGAACCC--------------CTAGGA
12
+ s echTel1.scaffold_304651 594 37 - 10007 -TGCTATGGCT--TTGTGTCTAGGAGGGGAATCC--------------CCAGGA
13
+
14
+ a score=-33148.0
15
+ s mm8.chr7 80082368 103 + 145134094 TGAGAGGGCATGCT-GTGAAGGGACTGTGCT---CAGTTCAAGGCATAGTCCACTTCC--------CTTCCCTTGGTCATTCTGTTCGGTGTGTTTCCAGCAGATATGGAGAGT-------------------------------------C----
16
+ s rn4.chr1 136011819 86 + 267910886 TGAGAGGGCATGTT-ATGAAGGCACTGTGCT--------------------CACTTTC--------CATCCCATGGTCATTCTGTTGAGTGTGTTCCCAGCAGATACGGAAAGT-------------------------------------C----
17
+ s oryCun1.scaffold_199771 14064 74 - 75077 TAGGACTGCCTGGTGGGGGGGGCCCTGCACC--------------------TACTTCTGCAAGGCACGTCCCGCG----------TCTGTGCCTTCGCCGCA-----------T-------------------------------------C----
18
+ s hg18.chr15 88557607 128 + 100338915 GGGGAAAGCCTGGT-TAAGGGGCCCTTCACCCCCCTCTCCAAGGCACATTCCCCTTTC--------TGTCCCTTTGTCGTTTCATTCACTCTACTCCCAGCATGGCTGGAGGGC---TTGTGG---CTGGCTCGTTTGG---------AGGC----
19
+ s panTro2.chr15 87959864 116 + 100063422 GGGGAAAGCCTGGT-TAAGGGGCCCTTCACCCCCCTCTCCAAGGCACATTCCCCTTTC--------TGTCCCTTTGTCGTTTCATTCACTA------------GGCTAGAGGGC---TTGTGG---CTGGCTCGTTTGG---------AGGC----
20
+ s rheMac2.chr7 69864742 107 + 169801366 GGAGAAAGCCTGGT-TAAGGGGCCCTTCA-----CTCTCCAAGGCACATTCCACTTTC--------TGTCCCTTTGTCATTCCATTCACTCTACTCCCCGCATGGCTAGAGGGC----------------------TGG---------AGGC----
21
+ s canFam2.chr3 56030609 103 + 94715083 AGGGAATGCATGGTGTATGGGGGCCCCCGTC--------------------CACTTC---------TGTCCCGTTGCTATTTCCTTGACCATACTTCCAGTATGACTGGGGGAG---GTGCGG---TGGAGCAGGTTC------------------
22
+ s loxAfr1.scaffold_8298 30302 144 + 78952 --TGGATGCCTGGT-TTAAGGATCC-GCTCACCCACTTCTGAGTCACGTTACACTTTC--------TGCCCCTTTGCCATTTCATTTATGGTACTCCCAACACCGGGGGAGGGTGCGCTTTGGTTCTTGAGCAGTTTGTGTATATAGGGGGCTGAG
23
+ s echTel1.scaffold_304651 631 67 - 10007 --TGGAGGGCTACT-TTAAGAAACC----CTCCCGTTTCTCAG-------------CC--------TGCTTC---------------------------------------------CTTTGGGTTTGAGGTACTTTGT----------------G
24
+
25
+ a score=87527.0
26
+ s mm8.chr7 80082471 121 + 145134094 CTG-AGC---------------CGCTGGCCCCTGGGCTTCCCCTCCAGCCTGGCTTGACTTTGTCTGAGGGACCCTGGGCAGC-TTGCCATCCA---------CCCAGGCTGAAGTGGAGGGGGTGTTGAGCTGCCACCTGGGACTT
27
+ s rn4.chr1 136011905 121 + 267910886 TCG-GAC---------------CGCTGGCACCCAGGCTTCCCCTCCAGCCTGGCCTGACTCTGTCTGAGGGACCCTGGGCAGC-TTGCCATCCA---------CGCAGGCAAAAGTGGAGGGGATGTTGAGCTGCCACCTGGAACTT
28
+ s oryCun1.scaffold_199771 14138 103 - 75077 CCGCAGT---------------GGATCCCACCTCGGCTGTAGCAGTAGGCCAACCAGG----GCCCGACAGGCGCCCGGCTGTGCTGGCTTCCA-CACCCTCTCCCAGGC---------------------CTGCCACCCAGGC---
29
+ s hg18.chr15 88557735 127 + 100338915 CTG-GGCTGAACCAGGGACT--GGCTGGTCTATAGGTTTCCCCTCCAGCC-GGCTGCACTCTG----TAGTGCCCGAGGCAGG-TTTCCACCCC-----TTCTCCCAGGCGTAAGTGGG------ATTGAGTTGCCACCTGGGACTG
30
+ s panTro2.chr15 87959980 127 + 100063422 CTG-GGCTGAACCAGGGACT--GGCTGGTCTATAGGTTTCCCCTCCAGCC-GGCTGCACTCTG----TAGTGCCCGTGGCAGG-TTTCCACCCC-----TTCTCCCAGGCGTAAGTGGG------ATTGAGTTGCCACCTGGGACTG
31
+ s rheMac2.chr7 69864849 116 + 169801366 CTG-GGCTGAACCAGGGGCT--GGCTGGTCTGCAG----------------GGCTGCACTCTGTCTATAGTGCCCGAGGCAGG-TTTCCACCCC-----TTCTTCCAGTCGTAAGTGGG------GTTGAGCTGCCACCTGGGACTG
32
+ s bosTau2.scaffold2397 93191 110 + 117874 CTG-GGC---------------AGCTGGCGCCTCGGCTGCCCCTCCCACCTGGCT-------------GTGACCCTTGGCAAG-TCTCCCCGCCCCCCATGCCCCCAGGCCTGAGCAAG------GCTGAGCTGCCACCT-GGACTA
33
+ s canFam2.chr3 56030712 116 + 94715083 TCT-AGC---------------AGCTGGCGCCCCAGCTGTCCTTCCAACCTGGCTGTGCTCTGTCTACGTGACCTTTGGCAGA-TTGCCACTCC-------CTCCCAGGCCCGAGCAGG------GCCAAGCTGCCACCT-GGATGG
34
+ s loxAfr1.scaffold_8298 30446 129 + 78952 CTG-AAC-----CAGGGACTGCAGCTAGTGCCTGGGCCACCGCTCCAGCCTGGCTGTGCTCTGTCTACAGGACGCATGGCAAG-TTGCCACCCC----CCTCTCCCAGG-CTAGGTGGG------GCTAAGCTGCCACTTGAAACTT
35
+ s echTel1.scaffold_304651 698 101 - 10007 CTG-GAC-----CAGGAACTGCAGCT---------GCTGCCCCTCTAGCCTACCTGTGC---------------CTTGGCAGG-TTGCCAGCCC-------CTCCCAGGCCTAGGTGGG------GTGACGCTGCCTCCTGGGAC--
36
+
37
+ a score=185399.0
38
+ s mm8.chr7 80082592 121 + 145134094 GTGCTTATCTCGGACTCTTGGCATTTCTGTTTCTGGACAGAACCCAAGGGTGGCTTCCCGCTTAGAGCTGTAGGTCCC----ACCCAGGTGGAAATG--CCCTCCGGTGCAGGCAGATAAGCTCTGG
39
+ s rn4.chr1 136012026 121 + 267910886 GTGCTTATCTTGGCCTCTTGGCATTTCTGTATCTGGACAGAATCCAAGGGTGGCTTCCCGCTTAGAGCTGTAGGTCCC----ACCCAGGTGGAAATG--CCCTCCGGAGCAGGCAGATAAGCTCTGG
40
+ s oryCun1.scaffold_199771 14241 119 - 75077 ---CTTATCTCCGACTGCTGGCATTGCTGTGTCTGGGCAGAGGCCAAGGGCGGCCTCCCGCACAGACACTCGGGGCCC----GCCCAGGTAGAAGTG-CCCCTCCTGTGCAGGCAGATAAGCGCTGG
41
+ s hg18.chr15 88557862 119 + 100338915 AGGCTTATCTCTGACTCTTGGCATTTCTTTGTCTGGACAGATTCCAAGGGCGGTCTGCTGCCCAGACTTACAGGGCCT----GCCCAGGTGGAAACG--CTCTTT--TGCAGGTAGATAAGCACGGG
42
+ s panTro2.chr15 87960107 119 + 100063422 AGGCTTATCTCTGACTCTTGGCATTTCTTTGTCTGGACAGATTCCAAGGGCGGTCTGCTGCCCAGACTTACAGGGCCT----GCCCAGGTGGAAACG--CTCTTT--TGCAGGTAGATAAGCACGGG
43
+ s rheMac2.chr7 69864965 114 + 169801366 AGGCTTATCTCTGATCCTTGGCATTTCTGTGTCTGGACAGATTCCAAGGGCGGTCTGCTGCCCAGACTTACAGGGCCC----GCCCAGGTG-----G--CTCTTC--TGCAGGTAGATAAGCATGGG
44
+ s bosTau2.scaffold2397 93301 123 + 117874 AAGCTTATCTCTGACCTTTGGCATTCCTGTGTGTGGACAGATTGCAAGAGCAGCCTCT-GCCCAGGCTTACGGGGACCTGCTGCCTCGGTAGAAATG-CGCCTCCTCTGTAGGCAGATAAGCCCT--
45
+ s canFam2.chr3 56030828 121 + 94715083 CAACTTATCTTTGACCTTCGGCATTTCTATATCTGGATGGATCCTAAGTGCAGCCTCCAGCCTAGACTTCCAGGACCC----ACCCTGGGA-AGATG-CCCCTCCTGTGTGGGCAGATAAATGTTGG
46
+ s echTel1.scaffold_304651 799 118 - 10007 ATGACAATCT--GACCTTTGACATT--TGTTTTAGGATAGGTTCCAAGTGAAGCCTCCTGCCTAGACTTCCTGATTCT-----CCCAGATAGAAGCGCCCCCTTCTTGGAAGACAGATAAGCGATAA
47
+
48
+ a score=30120.0
49
+ s mm8.chr7 80082713 54 + 145134094 CAA-------ACCAAAGGCAGCCTGT-GCTTCCAGAAAACCTT-GAGGGGTGCAAGAGATAAA
50
+ s rn4.chr1 136012147 54 + 267910886 CAA-------ACCAGAGGCAGCCTAC-GTTTCCAGAAAACCTT-GAGGGGTACAAGAGATAAA
51
+ s hg18.chr15 88557981 62 + 100338915 CAACCAGCTTATCTGAACCAGCCCTT-GCTTCCAGAGAACTATGGAAAAATCCAAAAGATAAG
52
+ s panTro2.chr15 87960226 62 + 100063422 CAACCAGCTTATCTGAACCAGCCCTT-GCTTCCAGAGAACTATGGAAAAATCCAAAAGATAAG
53
+ s rheMac2.chr7 69865079 62 + 169801366 CAACCAGCTTATCTGAACCAGCCCTC-GTTTCCAGGTAACTCTGGAAAAATCCAAAAGATGAG
54
+ s canFam2.chr3 56030949 40 + 94715083 -------CATATTTGACCCAGCCCTTGGCTTTCAGAAAACC------------ACAA----AG
55
+ s echTel1.scaffold_304651 917 55 - 10007 CAA-------ATTCCATCCCACCCTT-CGTTCTGGACGGGCTGGGAGGGGTACAAAAGATAAA
56
+
57
+ a score=58255.0
58
+ s mm8.chr7 80082767 128 + 145134094 GGGGTGCAGGAGCTGTG----TGTCTTGATCTCCCAGA----GTCTTCGTGAGCCT-----------CACTTTTTGTCTTATCCCT---GTGATACACACAGG-AAGCCACAGTGAATTCAGTGGGTGTCAT---------ACAGAAGGGCCTCC-TGGAG-
59
+ s rn4.chr1 136012201 139 + 267910886 GGGGTACAGGAGCTGTG----TG-CTTGATGTCGCTGA----GCCTTCGTGAGGCTCCTGTGAGCTGCACTTTTTGTCTCGTCCCT---GTGATAGACACAAG-AAGCCACAGTGAATTCAGTGGGTATCAT---------ATGGAAGGGCCTCCTTGGAC-
60
+ s hg18.chr15 88558043 143 + 100338915 AAGGGACCGCAG-TGTC----TGTCTTGGTCTCAC--------TCCTCTTGAGACTCCTGTGAT---CTTTATATGTCTCATTCCTCCCGTGACATGTATGAG-AAACTGCAGCTCATTGAGACGATGTCTCTGCTGCCTGACAGAAGGGCCTAC-TTGAG-
61
+ s panTro2.chr15 87960288 143 + 100063422 AAGGGACCGCAG-TGTC----TGTCTTGGTCTCAC--------TCCTCTTGAGACTCCTGTGAT---CTTTATATGTCTCATTCCTCCCGTGACATGTATGAG-AAACTGCAGCTCATTGAGACGATGTCTCTGCTGCCTGACAGAAGGGCCTAC-TTGAG-
62
+ s rheMac2.chr7 69865141 147 + 169801366 GAGGGACCACAG-TGTCTGTTTGTCCTGGTCTCAC--------TCCTCATGAGACTCCTGTGAT---CTTTGTATGTCTCATTCCTCCTGTGACATGTATGAG-AATGTACAGCTCAGTGAGATGATGTCTCTGCTGCCTGACAGAAGTGCCTAC-TTGAG-
63
+ s bosTau2.scaffold2397 93775 133 + 117874 GGACTGCAGTGGCCATT----TGCTCTGGCCTCACTGA----CTCCTTGTGAGCCCGCTGTGAG---TTTTGTTT---TCATTATCCCCAT------TATGAGAAAACTCCAGTTTGGTGAGATGGCATCTACCCTGCCCT--------ACAAAC-ATGgtg
64
+ s canFam2.chr3 56030989 153 + 94715083 GGGATGTGGAAGACGTT----TGCCCTCGTCTCACAGACTCCCTCCTTGTAAGGCTGCTGGGAG---TCATATTTTGCTCATTATCCCTGCGGTATGTATGAG-AAGCCAAAGGTCAGTGAGCTGGAGTTTGCACTGCCCTCCAGAGGGACCGAC-ATGgtg
65
+
66
+ a score=2607.0
67
+ s mm8.chr7 80082895 114 + 145134094 CTTCTCAGAGTGTAGT-----------CCTTGGGCTACC-TCCTCCTAAGTCACTGGG-----------------------AGCTGGTCA-AGAGG------CTCAGACCAGCAGTTTCAGAATCTCTTGGGAGGGCCT--------GGAGTCCGGGTGATGTT
68
+ s rn4.chr1 136012340 112 + 267910886 CTTCTCAGA--GTAGT-----------CCTTGGGCCACC-TCCTTCTAAGTTACTGAG-----------------------AGCTGGTCA-AGAGG------CTCAGACCAGCAGTTTCAGAATCTCTTGGGAGGGCCT--------GGAGTCAAGGTACTGTT
69
+ s rheMac2.chr7 69865323 119 + 169801366 CTTCTTGTTGACTAGTGTCACCCCCACCCGAGGGCTTCCTTCCTCATTTGCTGCCAGGTGTAAAGCTGAGCTTC-------agctgggcgcagtgg------ctcacacccataatcctagca--ttttgggag------------------------------
70
+ s bosTau2.scaffold2397 93908 136 + 117874 cttctcaaagtgtgct-----------ccatgagcctcc-tacttcagaatcccctgg---------gagattcaaaaccttgcatgttc-tcaggccccatcacgggccagcatcgtcagagtcttcagggtcagctcgtggatctagagtgtaggt------
71
+ s canFam2.chr3 56031142 126 + 94715083 cttttcagagggtggt-----------ccctgggcctcc-cactttggaattgcctgg---------gag-ctcatagaattgcccgttg-tcagg--ccatcccagggcagtggcagcag-gcctctagggcaggcct------------ttcaggtgacttt
72
+
73
+ a score=8132.0
74
+ s mm8.chr7 80083009 147 + 145134094 TAGGGAGGTTGGCATTGGTGCTGGAACTTTCCTTGGCCCCCCAATTTATCGAAGTACTAAGGGTTGGAAGTCTCTGGAGCTGCAGGAGTT--GAGTTTGAGAAAAGGCTCTTGGTGGTTTAAAGAGA----------------GGTTTCAACTGC--------------------------CTCTGGCCTC
75
+ s rn4.chr1 136012452 190 + 267910886 TAGGGAGATTGGGATTGGTACTGGAACTTTCCTTGGCCTCCCAGTGTATT-CAGTACTAAGGGTTGGAAGTCTCGGGTGCTACAAGAATTAAGAGTTTGAGAAGAGGCTCTTGGTAGTTTAGAAAGAGAGAAGGACATCTTTGGGTTTCGACTACCTGTGGTGGCAGTGTCAGAATTCAGGCTCTGGCCTC
76
+
@@ -0,0 +1,7 @@
1
+ ##maf version=1
2
+ a score=10542.0
3
+ s mm8.chr7 80082334 34 + 145134094 GGGCTGAGGGC--AGGGATGG---AGGGCGGTCC--------------CAGCA-
4
+ s rn4.chr1 136011785 34 + 267910886 GGGCTGAGGGC--AGGGACGG---AGGGCGGTCC--------------CAGCA-
5
+ s oryCun1.scaffold_199771 14021 43 - 75077 -----ATGGGC--AAGCGTGG---AGGGGAACCTCTCCTCCCCTCCGACAAAG-
6
+ s hg18.chr15 88557580 27 + 100338915 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
7
+ s hg181.chr15 87959837 27 + 100063422 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
@@ -0,0 +1,13 @@
1
+ ##maf version=1
2
+ a score=10542.0
3
+ s mm8.chr7 80082334 34 + 145134094 GGGCTGAGGGC--AGGGATGG---AGGGCGGTCC--------------CAGCA-
4
+ s rn4.chr1 136011785 34 + 267910886 GGGCTGAGGGC--AGGGACGG---AGGGCGGTCC--------------CAGCA-
5
+ s oryCun1.scaffold_199771 14021 43 - 75077 -----ATGGGC--AAGCGTGG---AGGGGAACCTCTCCTCCCCTCCGACAAAG-
6
+ s hg18.chr15 88557580 27 + 100338915 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
7
+ s panTro2.chr15 87959837 27 + 100063422 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
8
+ s rheMac2.chr7 69864714 28 + 169801366 -------GGGC--AAGTATGGA--AGGGAAGCCC--------------CAGAA-
9
+ s canFam2.chr3 56030570 39 + 94715083 AGGTTTAGGGCAGAGGGATGAAGGAGGAGAATCC--------------CTATG-
10
+ s dasNov1.scaffold_106893 7435 34 + 9831 GGAACGAGGGC--ATGTGTGG---AGGGGGCTGC--------------CCACA-
11
+ s loxAfr1.scaffold_8298 30264 38 + 78952 ATGATGAGGGG--AAGCGTGGAGGAGGGGAACCC--------------CTAGGA
12
+ s echTel1.scaffold_304651 594 37 - 10007 -TGCTATGGCT--TTGTGTCTAGGAGGGGAATCC--------------CCAGGA
13
+
@@ -0,0 +1,23 @@
1
+ ##maf version=1
2
+ a score=10542.0
3
+ s mm8.chr7 80082334 34 + 145134094 GGGCTGAGGGC--AGGGATGG---AGGGCGGTCC--------------CAGCA-
4
+ s rn4.chr1 136011785 34 + 267910886 GGGCTGAGGGC--AGGGACGG---AGGGCGGTCC--------------CAGCA-
5
+ s oryCun1.scaffold_199771 14021 43 - 75077 -----ATGGGC--AAGCGTGG---AGGGGAACCTCTCCTCCCCTCCGACAAAG-
6
+ s hg18.chr15 88557580 27 + 100338915 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
7
+ s panTro2.chr15 87959837 27 + 100063422 --------GGC--AAGTGTGGA--AGGGAAGCCC--------------CAGAA-
8
+ s rheMac2.chr7 69864714 28 + 169801366 -------GGGC--AAGTATGGA--AGGGAAGCCC--------------CAGAA-
9
+ s canFam2.chr3 56030570 39 + 94715083 AGGTTTAGGGCAGAGGGATGAAGGAGGAGAATCC--------------CTATG-
10
+ s dasNov1.scaffold_106893 7435 34 + 9831 GGAACGAGGGC--ATGTGTGG---AGGGGGCTGC--------------CCACA-
11
+ s loxAfr1.scaffold_8298 30264 38 + 78952 ATGATGAGGGG--AAGCGTGGAGGAGGGGAACCC--------------CTAGGA
12
+ s echTel1.scaffold_304651 594 37 - 10007 -TGCTATGGCT--TTGTGTCTAGGAGGGGAATCC--------------CCAGGA
13
+
14
+ a score=-33148.0
15
+ s mm8.chr7 80082368 103 + 145134094 TGAGAGGGCATGCT-GTGAAGGGACTGTGCT---CAGTTCAAGGCATAGTCCACTTCC--------CTTCCCTTGGTCATTCTGTTCGGTGTGTTTCCAGCAGATATGGAGAGT-------------------------------------C----
16
+ s rn4.chr1 136011819 86 + 267910886 TGAGAGGGCATGTT-ATGAAGGCACTGTGCT--------------------CACTTTC--------CATCCCATGGTCATTCTGTTGAGTGTGTTCCCAGCAGATACGGAAAGT-------------------------------------C----
17
+ s oryCun1.scaffold_199771 14064 74 - 75077 TAGGACTGCCTGGTGGGGGGGGCCCTGCACC--------------------TACTTCTGCAAGGCACGTCCCGCG----------TCTGTGCCTTCGCCGCA-----------T-------------------------------------C----
18
+ s hg18.chr15 88557607 128 + 100338915 GGGGAAAGCCTGGT-TAAGGGGCCCTTCACCCCCCTCTCCAAGGCACATTCCCCTTTC--------TGTCCCTTTGTCGTTTCATTCACTCTACTCCCAGCATGGCTGGAGGGC---TTGTGG---CTGGCTCGTTTGG---------AGGC----
19
+ s panTro2.chr15 87959864 116 + 100063422 GGGGAAAGCCTGGT-TAAGGGGCCCTTCACCCCCCTCTCCAAGGCACATTCCCCTTTC--------TGTCCCTTTGTCGTTTCATTCACTA------------GGCTAGAGGGC---TTGTGG---CTGGCTCGTTTGG---------AGGC----
20
+ s rheMac2.chr7 69864742 107 + 169801366 GGAGAAAGCCTGGT-TAAGGGGCCCTTCA-----CTCTCCAAGGCACATTCCACTTTC--------TGTCCCTTTGTCATTCCATTCACTCTACTCCCCGCATGGCTAGAGGGC----------------------TGG---------AGGC----
21
+ s canFam2.chr3 56030609 103 + 94715083 AGGGAATGCATGGTGTATGGGGGCCCCCGTC--------------------CACTTC---------TGTCCCGTTGCTATTTCCTTGACCATACTTCCAGTATGACTGGGGGAG---GTGCGG---TGGAGCAGGTTC------------------
22
+ s loxAfr1.scaffold_8298 30302 144 + 78952 --TGGATGCCTGGT-TTAAGGATCC-GCTCACCCACTTCTGAGTCACGTTACACTTTC--------TGCCCCTTTGCCATTTCATTTATGGTACTCCCAACACCGGGGGAGGGTGCGCTTTGGTTCTTGAGCAGTTTGTGTATATAGGGGGCTGAG
23
+ s echTel1.scaffold_304651 631 67 - 10007 --TGGAGGGCTACT-TTAAGAAACC----CTCCCGTTTCTCAG-------------CC--------TGCTTC---------------------------------------------CTTTGGGTTTGAGGTACTTTGT----------------G
@@ -0,0 +1,15 @@
1
+ ##maf version=1 scoring=humor.v4
2
+ # humor.v4 R=30 M=10 /cluster/data/hg15/bed/blastz.mm3/axtNet300/chr1.maf
3
+ # /cluster/data/hg15/bed/blastz.rn3/axtNet300/chr1.maf
4
+
5
+ a score=0.128
6
+ s human_hoxa 100 8 + 100257 ACA-TTACT
7
+ s horse_hoxa 120 9 - 98892 ACAATTGCT
8
+ s fugu_hoxa 88 7 + 90788 ACA--TGCT
9
+
10
+
11
+ a score=0.071
12
+ s human_unc 9077 8 + 10998 ACAGTATT
13
+ # Comment
14
+ s horse_unc 4555 6 - 5099 ACA--ATT
15
+ s fugu_unc 4000 4 + 4038 AC----TT
@@ -0,0 +1,12 @@
1
+ >human_hoxa:100-108
2
+ ACA-TTACT
3
+ >horse_hoxa:120-129
4
+ ACAATTGCT
5
+ >fugu_hoxa:88-95
6
+ ACA--TGCT
7
+ >human_unc:9077-9085
8
+ ACAGTATT
9
+ >horse_unc:4555-4561
10
+ ACA--ATT
11
+ >fugu_unc:4000-4004
12
+ AC----TT
data/test/data/t1.maf ADDED
@@ -0,0 +1,15 @@
1
+ ##maf version=1 scoring=humor.v4
2
+ # humor.v4 R=30 M=10 /cluster/data/hg15/bed/blastz.mm3/axtNet300/chr1.maf
3
+ # /cluster/data/hg15/bed/blastz.rn3/axtNet300/chr1.maf
4
+
5
+ a score=0.128
6
+ s human_hoxa 100 8 + 100257 ACA-TTACT
7
+ s horse_hoxa 120 9 - 98892 ACAATTGCT
8
+ s fugu_hoxa 88 7 + 90788 ACA--TGCT
9
+
10
+
11
+ a score=0.071
12
+ s human_unc 9077 8 + 10998 ACAGTATT
13
+ # Comment
14
+ s horse_unc 4555 6 - 5099 ACA--ATT
15
+ s fugu_unc 4000 4 + 4038 AC----TT
data/test/data/t1a.maf ADDED
@@ -0,0 +1,17 @@
1
+ ##maf version=1 scoring=humor.v4
2
+ # humor.v4 R=30 M=10 /cluster/data/hg15/bed/blastz.mm3/axtNet300/chr1.maf
3
+ # /cluster/data/hg15/bed/blastz.rn3/axtNet300/chr1.maf
4
+
5
+ a score=0.128
6
+ s human_hoxa 100 8 + 100257 ACA-TTACT
7
+ s horse_hoxa 120 9 - 98892 ACAATTGCT
8
+ s fugu_hoxa 88 7 + 90788 ACA--TGCT
9
+
10
+
11
+ a score=0.071
12
+ s human_unc 9077 8 + 10998 ACAGTATT
13
+ # Comment
14
+ s horse_unc 4555 6 - 5099 ACA--ATT
15
+ s fugu_unc 4000 4 + 4038 AC----TT
16
+
17
+ ##eof maf
data/test/helper.rb ADDED
@@ -0,0 +1,18 @@
1
+ require 'rubygems'
2
+ require 'bundler'
3
+ begin
4
+ Bundler.setup(:default, :development)
5
+ rescue Bundler::BundlerError => e
6
+ $stderr.puts e.message
7
+ $stderr.puts "Run `bundle install` to install missing gems"
8
+ exit e.status_code
9
+ end
10
+ require 'test/unit'
11
+ require 'shoulda'
12
+
13
+ $LOAD_PATH.unshift(File.join(File.dirname(__FILE__), '..', 'lib'))
14
+ $LOAD_PATH.unshift(File.dirname(__FILE__))
15
+ require 'bio-maf'
16
+
17
+ class Test::Unit::TestCase
18
+ end
@@ -0,0 +1,7 @@
1
+ require 'helper'
2
+
3
+ class TestBioMaf < Test::Unit::TestCase
4
+ should "probably rename this file and start testing for real" do
5
+ flunk "hey buddy, you should probably rename this file and start testing for real"
6
+ end
7
+ end
@@ -0,0 +1,13 @@
1
+ #!/bin/bash
2
+
3
+ ## NOTE: I am aware that this shell script is horrible.
4
+
5
+ cd /tmp
6
+ wget http://fallabs.com/kyotocabinet/pkg/kyotocabinet-1.2.76.tar.gz
7
+ tar xzf kyotocabinet-1.2.76.tar.gz
8
+ cd kyotocabinet-1.2.76
9
+ ./configure && make && make install
10
+ grep -q local /etc/ld.so.conf
11
+ if [ $? -ne 0 ]; then
12
+ echo "/usr/local/lib" >> /etc/ld.so.conf && ldconfig
13
+ fi
@@ -0,0 +1,13 @@
1
+ #!/bin/bash
2
+
3
+ ## NOTE: I am aware that this shell script is horrible.
4
+
5
+ export JAVA_HOME=/usr/lib/jvm/java-7-openjdk-i386
6
+
7
+ cd /tmp
8
+ wget http://fallabs.com/kyotocabinet/javapkg/kyotocabinet-java-1.24.tar.gz
9
+ tar xzf kyotocabinet-java-1.24.tar.gz
10
+ cd kyotocabinet-java-1.24
11
+ ./configure && make && make install
12
+ cp -Rf /usr/local/lib/libjkyotocabinet.so* /usr/lib/jni/
13
+ ldconfig
@@ -0,0 +1,4 @@
1
+ #!/bin/bash
2
+
3
+ cat $HOME/builds/csw/bioruby-maf/hs*.log 2>/dev/null
4
+ exit 0
metadata ADDED
@@ -0,0 +1,181 @@
1
+ --- !ruby/object:Gem::Specification
2
+ name: bio-maf
3
+ version: !ruby/object:Gem::Version
4
+ version: 0.1.0
5
+ prerelease:
6
+ platform: ruby
7
+ authors:
8
+ - Clayton Wheeler
9
+ autorequire:
10
+ bindir: bin
11
+ cert_chain: []
12
+ date: 2012-06-29 00:00:00.000000000 Z
13
+ dependencies:
14
+ - !ruby/object:Gem::Dependency
15
+ name: bio-bigbio
16
+ requirement: !ruby/object:Gem::Requirement
17
+ none: false
18
+ requirements:
19
+ - - ! '>='
20
+ - !ruby/object:Gem::Version
21
+ version: '0'
22
+ type: :runtime
23
+ prerelease: false
24
+ version_requirements: !ruby/object:Gem::Requirement
25
+ none: false
26
+ requirements:
27
+ - - ! '>='
28
+ - !ruby/object:Gem::Version
29
+ version: '0'
30
+ - !ruby/object:Gem::Dependency
31
+ name: bio-genomic-interval
32
+ requirement: !ruby/object:Gem::Requirement
33
+ none: false
34
+ requirements:
35
+ - - ~>
36
+ - !ruby/object:Gem::Version
37
+ version: 0.1.2
38
+ type: :runtime
39
+ prerelease: false
40
+ version_requirements: !ruby/object:Gem::Requirement
41
+ none: false
42
+ requirements:
43
+ - - ~>
44
+ - !ruby/object:Gem::Version
45
+ version: 0.1.2
46
+ - !ruby/object:Gem::Dependency
47
+ name: kyotocabinet-ruby
48
+ requirement: !ruby/object:Gem::Requirement
49
+ none: false
50
+ requirements:
51
+ - - ~>
52
+ - !ruby/object:Gem::Version
53
+ version: 1.27.1
54
+ type: :runtime
55
+ prerelease: false
56
+ version_requirements: !ruby/object:Gem::Requirement
57
+ none: false
58
+ requirements:
59
+ - - ~>
60
+ - !ruby/object:Gem::Version
61
+ version: 1.27.1
62
+ description: Multiple Alignment Format parser for BioRuby.
63
+ email: cswh@umich.edu
64
+ executables:
65
+ - maf_count
66
+ - maf_dump_blocks
67
+ - maf_extract_ranges_count
68
+ - maf_index
69
+ - maf_parse_bench
70
+ - maf_to_fasta
71
+ - maf_write
72
+ - random_ranges
73
+ extensions: []
74
+ extra_rdoc_files:
75
+ - LICENSE.txt
76
+ - README.md
77
+ files:
78
+ - .document
79
+ - .simplecov
80
+ - .travis.yml
81
+ - .yardopts
82
+ - DEVELOPMENT.md
83
+ - Gemfile
84
+ - LICENSE.txt
85
+ - README.md
86
+ - Rakefile
87
+ - VERSION
88
+ - benchmarks/dispatch_bench
89
+ - benchmarks/iter_bench
90
+ - benchmarks/read_bench
91
+ - benchmarks/sort_bench
92
+ - benchmarks/split_bench
93
+ - bin/maf_count
94
+ - bin/maf_dump_blocks
95
+ - bin/maf_extract_ranges_count
96
+ - bin/maf_index
97
+ - bin/maf_parse_bench
98
+ - bin/maf_to_fasta
99
+ - bin/maf_write
100
+ - bin/random_ranges
101
+ - features/maf-indexing.feature
102
+ - features/maf-output.feature
103
+ - features/maf-parsing.feature
104
+ - features/maf-querying.feature
105
+ - features/maf-to-fasta.feature
106
+ - features/step_definitions/convert_steps.rb
107
+ - features/step_definitions/index_steps.rb
108
+ - features/step_definitions/output_steps.rb
109
+ - features/step_definitions/parse_steps.rb
110
+ - features/step_definitions/query_steps.rb
111
+ - features/step_definitions/ucsc_bin_steps.rb
112
+ - features/support/env.rb
113
+ - features/ucsc-bins.feature
114
+ - lib/bio-maf.rb
115
+ - lib/bio-maf/maf.rb
116
+ - lib/bio/maf.rb
117
+ - lib/bio/maf/index.rb
118
+ - lib/bio/maf/parser.rb
119
+ - lib/bio/maf/struct.rb
120
+ - lib/bio/maf/writer.rb
121
+ - lib/bio/ucsc.rb
122
+ - lib/bio/ucsc/genomic-interval-bin.rb
123
+ - lib/bio/ucsc/ucsc_bin.rb
124
+ - man/.gitignore
125
+ - man/maf_index.1
126
+ - man/maf_index.1.markdown
127
+ - man/maf_index.1.ronn
128
+ - man/maf_to_fasta.1
129
+ - man/maf_to_fasta.1.ronn
130
+ - spec/bio/maf/index_spec.rb
131
+ - spec/bio/maf/parser_spec.rb
132
+ - spec/bio/maf/struct_spec.rb
133
+ - spec/spec_helper.rb
134
+ - test/data/big-block.maf
135
+ - test/data/chr22_ieq.maf
136
+ - test/data/chrY-1block.maf
137
+ - test/data/empty
138
+ - test/data/empty.db
139
+ - test/data/mm8_chr7_tiny.kct
140
+ - test/data/mm8_chr7_tiny.maf
141
+ - test/data/mm8_mod_a.maf
142
+ - test/data/mm8_single.maf
143
+ - test/data/mm8_subset_a.maf
144
+ - test/data/t1-bad1.maf
145
+ - test/data/t1.fasta
146
+ - test/data/t1.maf
147
+ - test/data/t1a.maf
148
+ - test/helper.rb
149
+ - test/test_bio-maf.rb
150
+ - travis-ci/install_kc
151
+ - travis-ci/install_kc_java
152
+ - travis-ci/report_errors
153
+ homepage: http://github.com/csw/bioruby-maf
154
+ licenses:
155
+ - MIT
156
+ post_install_message:
157
+ rdoc_options: []
158
+ require_paths:
159
+ - lib
160
+ required_ruby_version: !ruby/object:Gem::Requirement
161
+ none: false
162
+ requirements:
163
+ - - ! '>='
164
+ - !ruby/object:Gem::Version
165
+ version: '0'
166
+ segments:
167
+ - 0
168
+ hash: -2212073295752934712
169
+ required_rubygems_version: !ruby/object:Gem::Requirement
170
+ none: false
171
+ requirements:
172
+ - - ! '>='
173
+ - !ruby/object:Gem::Version
174
+ version: '0'
175
+ requirements: []
176
+ rubyforge_project:
177
+ rubygems_version: 1.8.24
178
+ signing_key:
179
+ specification_version: 3
180
+ summary: MAF parser for BioRuby
181
+ test_files: []