bio-bigwig 0.0.1 → 0.0.3
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- checksums.yaml +4 -4
- data/README.md +11 -14
- data/ext/bio/bigwig/bigwigext.c +1 -1
- data/ext/bio/bigwig/extconf.rb +7 -25
- data/ext/bio/bigwig/libBigWig/bigWig.h +20 -20
- data/ext/bio/bigwig/libBigWig/bigWigIO.h +2 -2
- data/ext/bio/bigwig/libBigWig/bwCommon.h +4 -0
- data/ext/bio/bigwig/libBigWig/bwRead.c +21 -10
- data/ext/bio/bigwig/libBigWig/bwStats.c +4 -4
- data/ext/bio/bigwig/libBigWig/bwValues.c +18 -18
- data/ext/bio/bigwig/libBigWig/bwWrite.c +11 -11
- data/ext/bio/bigwig/libBigWig/io.c +3 -3
- data/lib/bio/bigwig/version.rb +1 -1
- metadata +4 -11
- data/ext/bio/bigwig/libBigWig/test/exampleWrite.c +0 -76
- data/ext/bio/bigwig/libBigWig/test/testBigBed.c +0 -132
- data/ext/bio/bigwig/libBigWig/test/testIterator.c +0 -67
- data/ext/bio/bigwig/libBigWig/test/testLocal.c +0 -223
- data/ext/bio/bigwig/libBigWig/test/testRemote.c +0 -203
- data/ext/bio/bigwig/libBigWig/test/testRemoteManyContigs.c +0 -46
- data/ext/bio/bigwig/libBigWig/test/testWrite.c +0 -68
@@ -1,203 +0,0 @@
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-
#include "bigWig.h"
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#include <stdio.h>
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#include <inttypes.h>
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#include <stdlib.h>
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#include <assert.h>
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7
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//Print overly verbose header information
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void bwPrintHdr(bigWigFile_t *bw) {
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uint64_t i;
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int64_t i64;
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printf("Version: %"PRIu16"\n", bw->hdr->version);
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12
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printf("Levels: %"PRIu16"\n", bw->hdr->nLevels);
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printf("ctOffset: 0x%"PRIx64"\n", bw->hdr->ctOffset);
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printf("dataOffset: 0x%"PRIx64"\n", bw->hdr->dataOffset);
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printf("indexOffset: 0x%"PRIx64"\n", bw->hdr->indexOffset);
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printf("sqlOffset: 0x%"PRIx64"\n", bw->hdr->sqlOffset);
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printf("summaryOffset: 0x%"PRIx64"\n", bw->hdr->summaryOffset);
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printf("bufSize: %"PRIu32"\n", bw->hdr->bufSize);
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printf("extensionOffset: 0x%"PRIx64"\n", bw->hdr->extensionOffset);
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20
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if(bw->hdr->nLevels) {
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printf(" i level data index\n");
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}
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24
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for(i=0; i<bw->hdr->nLevels; i++) {
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printf("\t%"PRIu64"\t%"PRIu32"\t%"PRIx64"\t%"PRIx64"\n", i, bw->hdr->zoomHdrs->level[i], bw->hdr->zoomHdrs->dataOffset[i], bw->hdr->zoomHdrs->indexOffset[i]);
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26
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-
}
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27
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28
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printf("nBasesCovered: %"PRIu64"\n", bw->hdr->nBasesCovered);
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29
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printf("minVal: %f\n", bw->hdr->minVal);
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30
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printf("maxVal: %f\n", bw->hdr->maxVal);
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printf("sumData: %f\n", bw->hdr->sumData);
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printf("sumSquared: %f\n", bw->hdr->sumSquared);
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//Chromosome idx/name/length
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if(bw->cl) {
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printf("Chromosome List\n");
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printf(" idx\tChrom\tLength (bases)\n");
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for(i64=0; i64<bw->cl->nKeys; i64++) {
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printf(" %"PRIu64"\t%s\t%"PRIu32"\n", i64, bw->cl->chrom[i64], bw->cl->len[i64]);
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}
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}
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}
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void bwPrintIndexNode(bwRTreeNode_t *node, int level) {
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uint16_t i;
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if(!node) return;
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for(i=0; i<node->nChildren; i++) {
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if(node->isLeaf) {
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printf(" %i\t%"PRIu32"\t%"PRIu32"\t%"PRIu32"\t%"PRIu32"\t0x%"PRIx64"\t%"PRIu64"\n", level,\
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50
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node->chrIdxStart[i], \
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node->baseStart[i], \
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node->chrIdxEnd[i], \
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node->baseEnd[i], \
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node->dataOffset[i], \
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node->x.size[i]);
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} else {
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printf(" %i\t%"PRIu32"\t%"PRIu32"\t%"PRIu32"\t%"PRIu32"\t0x%"PRIx64"\tNA\n", level,\
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node->chrIdxStart[i], \
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node->baseStart[i], \
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node->chrIdxEnd[i], \
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node->baseEnd[i], \
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node->dataOffset[i]);
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bwPrintIndexNode(node->x.child[i], level+1);
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}
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}
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}
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67
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void bwPrintIndexTree(bigWigFile_t *fp) {
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printf("\nIndex tree:\n");
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70
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printf("nItems:\t%"PRIu64"\n", fp->idx->nItems);
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71
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printf("chrIdxStart:\t%"PRIu32"\n", fp->idx->chrIdxStart);
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72
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printf("baseStart:\t%"PRIu32"\n", fp->idx->baseStart);
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73
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printf("chrIdxEnd:\t%"PRIu32"\n", fp->idx->chrIdxEnd);
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printf("baseEnd:\t%"PRIu32"\n", fp->idx->baseEnd);
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printf("idxSize:\t%"PRIu64"\n", fp->idx->idxSize);
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printf(" level\tchrIdxStart\tbaseStart\tchrIdxEnd\tbaseEnd\tchild\tsize\n");
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bwPrintIndexNode(fp->idx->root, 0);
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}
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79
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80
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void printIntervals(bwOverlappingIntervals_t *ints, uint32_t start) {
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81
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uint32_t i;
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82
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if(!ints) return;
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83
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for(i=0; i<ints->l; i++) {
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84
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if(ints->start && ints->end) {
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85
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printf("Interval %"PRIu32"\t%"PRIu32"-%"PRIu32": %f\n",i, ints->start[i], ints->end[i], ints->value[i]);
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86
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} else if(ints->start) {
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87
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printf("Interval %"PRIu32"\t%"PRIu32"-%"PRIu32": %f\n",i, ints->start[i], ints->start[i]+1, ints->value[i]);
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} else {
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89
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printf("Interval %"PRIu32"\t%"PRIu32"-%"PRIu32": %f\n",i, start+i, start+i+1, ints->value[i]);
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}
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91
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}
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92
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}
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93
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94
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//This is an example call back function
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95
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CURLcode callBack(CURL *curl) {
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96
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CURLcode rv;
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97
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98
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rv = curl_easy_setopt(curl, CURLOPT_USERNAME, "anonymous");
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if(rv != CURLE_OK) return rv;
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101
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rv = curl_easy_setopt(curl, CURLOPT_PASSWORD, "libBigWig@github.com");
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return rv;
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103
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}
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104
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105
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int main(int argc, char *argv[]) {
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106
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bigWigFile_t *fp = NULL;
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107
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bwOverlappingIntervals_t *intervals = NULL;
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108
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double *stats = NULL;
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109
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char chrom[] = "chr1";
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if(argc != 2) {
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111
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fprintf(stderr, "Usage: %s {file.bw|URL://path/file.bw}\n", argv[0]);
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return 1;
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113
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}
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114
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115
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if(bwInit(1<<17) != 0) {
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fprintf(stderr, "Received an error in bwInit\n");
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return 1;
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118
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}
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119
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120
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fp = bwOpen(argv[1], callBack, "r");
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if(!fp) {
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122
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fprintf(stderr, "An error occured while opening %s\n", argv[1]);
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return 1;
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}
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126
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bwPrintHdr(fp);
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bwPrintIndexTree(fp);
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128
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129
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//Try to get some blocks
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printf("%s:10000000-10000100 Intervals\n", chrom);
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131
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intervals = bwGetOverlappingIntervals(fp, chrom, 10000000, 10000100);
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printIntervals(intervals,0);
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bwDestroyOverlappingIntervals(intervals);
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printf("%s:10000000-10000100 Values\n", chrom);
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intervals = bwGetValues(fp, chrom, 10000000, 10000100, 0);
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printIntervals(intervals,0);
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bwDestroyOverlappingIntervals(intervals);
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stats = bwStats(fp, chrom, 10000000, 10000100, 1, mean);
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if(stats) {
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printf("%s:10000000-10000100 mean: %f\n", chrom, stats[0]);
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free(stats);
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}
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stats = bwStats(fp, chrom, 10000000, 10000100, 2, mean);
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if(stats) {
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printf("%s:10000000-10000100 mean: %f %f\n", chrom, stats[0], stats[1]);
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free(stats);
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}
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stats = bwStats(fp, chrom, 10000000, 10000100, 1, dev);
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if(stats) {
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printf("%s:10000000-10000100 std. dev.: %f\n", chrom, stats[0]);
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free(stats);
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}
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stats = bwStats(fp, chrom, 10000000, 10000100, 2, dev);
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if(stats) {
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printf("%s:10000000-10000100 std. dev.: %f %f\n", chrom, stats[0], stats[1]);
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free(stats);
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}
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164
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stats = bwStats(fp, chrom, 10000000, 10000100, 1, min);
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if(stats) {
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printf("%s:10000000-10000100 min: %f\n", chrom, stats[0]);
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free(stats);
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}
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170
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stats = bwStats(fp, chrom, 10000000, 10000100, 2, min);
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if(stats) {
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printf("%s:10000000-10000100 min: %f %f\n", chrom, stats[0], stats[1]);
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free(stats);
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}
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stats = bwStats(fp, chrom, 10000000, 10000100, 1, max);
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if(stats) {
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printf("%s:10000000-10000100 max: %f\n", chrom, stats[0]);
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free(stats);
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}
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182
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stats = bwStats(fp, chrom, 10000000, 10000100, 2, max);
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183
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if(stats) {
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184
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printf("%s:10000000-10000100 max: %f %f\n", chrom, stats[0], stats[1]);
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185
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free(stats);
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186
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}
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187
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188
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stats = bwStats(fp, chrom, 10000000, 10000100, 1, cov);
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189
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if(stats) {
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190
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printf("%s:10000000-10000100 coverage: %f\n", chrom, stats[0]);
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191
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free(stats);
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192
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}
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193
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194
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stats = bwStats(fp, chrom, 10000000, 10000100, 2, cov);
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195
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if(stats) {
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196
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printf("%s:10000000-10000100 coverage: %f %f\n", chrom, stats[0], stats[1]);
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197
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free(stats);
|
198
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}
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199
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200
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bwClose(fp);
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201
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bwCleanup();
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202
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return 0;
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203
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}
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@@ -1,46 +0,0 @@
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1
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-
#include "bigWig.h"
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2
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#include <stdio.h>
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3
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-
#include <inttypes.h>
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4
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-
#include <stdlib.h>
|
5
|
-
#include <assert.h>
|
6
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-
|
7
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-
//This is an example call back function
|
8
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-
CURLcode callBack(CURL *curl) {
|
9
|
-
CURLcode rv;
|
10
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-
|
11
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-
rv = curl_easy_setopt(curl, CURLOPT_USERNAME, "anonymous");
|
12
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if(rv != CURLE_OK) return rv;
|
13
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-
|
14
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-
rv = curl_easy_setopt(curl, CURLOPT_PASSWORD, "libBigWig@github.com");
|
15
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return rv;
|
16
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-
}
|
17
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|
18
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int main(int argc, char *argv[]) {
|
19
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bigWigFile_t *fp = NULL;
|
20
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int64_t i;
|
21
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-
|
22
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-
if(argc != 2) {
|
23
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fprintf(stderr, "Usage: %s {file.bw|URL://path/file.bw}\n", argv[0]);
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24
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return 1;
|
25
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-
}
|
26
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-
|
27
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if(bwInit(1<<17) != 0) {
|
28
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fprintf(stderr, "Received an error in bwInit\n");
|
29
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-
return 1;
|
30
|
-
}
|
31
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-
|
32
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-
fp = bwOpen(argv[1], callBack, "r");
|
33
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if(!fp) {
|
34
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fprintf(stderr, "An error occured while opening %s\n", argv[1]);
|
35
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-
return 1;
|
36
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-
}
|
37
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-
|
38
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//Return the number of chromosomes/contigs
|
39
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for(i=0; i<fp->cl->nKeys; i++) {
|
40
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printf("%s\t%"PRIu32"\n", fp->cl->chrom[i], fp->cl->len[i]);
|
41
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-
}
|
42
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-
|
43
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-
bwClose(fp);
|
44
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-
bwCleanup();
|
45
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-
return 0;
|
46
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-
}
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@@ -1,68 +0,0 @@
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1
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-
#include "bigWig.h"
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2
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-
#include <stdio.h>
|
3
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-
#include <inttypes.h>
|
4
|
-
#include <stdlib.h>
|
5
|
-
#include <assert.h>
|
6
|
-
|
7
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-
int main(int argc, char *argv[]) {
|
8
|
-
bigWigFile_t *ifp = NULL;
|
9
|
-
bigWigFile_t *ofp = NULL;
|
10
|
-
uint32_t tid, i;
|
11
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char **chroms;
|
12
|
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bwOverlappingIntervals_t *o;
|
13
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-
if(argc != 3) {
|
14
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-
fprintf(stderr, "Usage: %s {inputfile.bw|URL://path/inputfile.bw} outputfile.bw\n", argv[0]);
|
15
|
-
return 1;
|
16
|
-
}
|
17
|
-
|
18
|
-
if(bwInit(1<<17) != 0) {
|
19
|
-
fprintf(stderr, "Received an error in bwInit\n");
|
20
|
-
return 1;
|
21
|
-
}
|
22
|
-
|
23
|
-
ifp = bwOpen(argv[1], NULL, "r");
|
24
|
-
if(!ifp) {
|
25
|
-
fprintf(stderr, "An error occured while opening %s\n", argv[1]);
|
26
|
-
return 1;
|
27
|
-
}
|
28
|
-
|
29
|
-
ofp = bwOpen(argv[2], NULL, "w");
|
30
|
-
if(!ofp) {
|
31
|
-
bwClose(ifp);
|
32
|
-
fprintf(stderr, "An error occured while opening %s\n", argv[2]);
|
33
|
-
return 1;
|
34
|
-
}
|
35
|
-
|
36
|
-
if(bwCreateHdr(ofp, 10)) goto error; //ten zoom levels
|
37
|
-
ofp->cl = bwCreateChromList(ifp->cl->chrom, ifp->cl->len, ifp->cl->nKeys);
|
38
|
-
if(!ofp->cl) goto error;
|
39
|
-
|
40
|
-
if(bwWriteHdr(ofp)) goto error;
|
41
|
-
|
42
|
-
//Copy all of the intervals
|
43
|
-
for(tid = 0; tid < ofp->cl->nKeys; tid++) {
|
44
|
-
o = bwGetOverlappingIntervals(ifp, ofp->cl->chrom[tid], 0, ofp->cl->len[tid]);
|
45
|
-
if(!o) goto error;
|
46
|
-
if(o->l) {
|
47
|
-
chroms = malloc(o->l * sizeof(char*));
|
48
|
-
if(!chroms) goto error;
|
49
|
-
for(i=0; i<o->l; i++) chroms[i] = ofp->cl->chrom[tid];
|
50
|
-
bwAddIntervals(ofp, chroms, o->start, o->end, o->value, o->l);
|
51
|
-
free(chroms);
|
52
|
-
}
|
53
|
-
bwDestroyOverlappingIntervals(o);
|
54
|
-
}
|
55
|
-
|
56
|
-
bwClose(ifp);
|
57
|
-
bwClose(ofp);
|
58
|
-
bwCleanup();
|
59
|
-
|
60
|
-
return 0;
|
61
|
-
|
62
|
-
error:
|
63
|
-
fprintf(stderr, "Got an error somewhere!\n");
|
64
|
-
bwClose(ifp);
|
65
|
-
bwClose(ofp);
|
66
|
-
bwCleanup();
|
67
|
-
return 1;
|
68
|
-
}
|