bento_search 1.5.0 → 2.0.0.rc1

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Files changed (61) hide show
  1. checksums.yaml +5 -5
  2. data/README.md +27 -24
  3. data/Rakefile +30 -11
  4. data/app/assets/javascripts/bento_search/ajax_load.js +54 -22
  5. data/app/controllers/bento_search/search_controller.rb +31 -30
  6. data/app/helpers/bento_search_helper.rb +72 -74
  7. data/app/models/bento_search/concurrent_searcher.rb +136 -0
  8. data/app/models/bento_search/result_item.rb +15 -12
  9. data/app/models/bento_search/results/serialization.rb +22 -13
  10. data/app/models/bento_search/search_engine.rb +170 -140
  11. data/app/search_engines/bento_search/doaj_articles_engine.rb +20 -20
  12. data/app/search_engines/bento_search/ebsco_host_engine.rb +3 -3
  13. data/app/search_engines/bento_search/eds_engine.rb +326 -206
  14. data/app/search_engines/bento_search/google_books_engine.rb +2 -2
  15. data/app/search_engines/bento_search/scopus_engine.rb +87 -87
  16. data/app/search_engines/bento_search/summon_engine.rb +1 -1
  17. data/app/views/bento_search/_ajax_loading.html.erb +17 -0
  18. data/app/views/bento_search/_item_title.html.erb +2 -4
  19. data/app/views/bento_search/_link.html.erb +3 -3
  20. data/lib/bento_search.rb +24 -9
  21. data/lib/bento_search/engine.rb +2 -0
  22. data/lib/bento_search/version.rb +1 -1
  23. data/lib/generators/bento_search/install/ajax_load_js_generator.rb +15 -0
  24. data/test/decorator/standard_decorator_test.rb +30 -30
  25. data/test/dummy/app/assets/config/manifest.js +4 -0
  26. data/test/dummy/config/application.rb +7 -0
  27. data/test/dummy/config/boot.rb +4 -9
  28. data/test/dummy/config/environments/development.rb +2 -0
  29. data/test/dummy/config/environments/production.rb +7 -1
  30. data/test/dummy/config/environments/test.rb +10 -3
  31. data/test/functional/bento_search/search_controller_test.rb +68 -58
  32. data/test/helper/bento_search_helper_test.rb +103 -103
  33. data/test/search_engines/doaj_articles_engine_test.rb +9 -9
  34. data/test/search_engines/eds_engine_test.rb +91 -59
  35. data/test/search_engines/google_site_search_test.rb +48 -48
  36. data/test/search_engines/scopus_engine_test.rb +51 -51
  37. data/test/search_engines/search_engine_base_test.rb +108 -86
  38. data/test/search_engines/search_engine_test.rb +68 -56
  39. data/test/support/atom.xsd.xml +3 -3
  40. data/test/support/xml.xsd +117 -0
  41. data/test/test_helper.rb +23 -12
  42. data/test/unit/concurrent_searcher_test.rb +75 -0
  43. data/test/unit/pagination_test.rb +12 -12
  44. data/test/vcr_cassettes/eds/FullText_CustomLink.yml +198 -0
  45. data/test/vcr_cassettes/eds/basic_search_smoke_test.yml +1036 -1729
  46. data/test/vcr_cassettes/eds/catalog_ebook_query.yml +218 -0
  47. data/test/vcr_cassettes/eds/catalog_query.yml +255 -0
  48. data/test/vcr_cassettes/eds/get_auth_token.yml +11 -44
  49. data/test/vcr_cassettes/eds/get_auth_token_failure.yml +10 -7
  50. data/test/vcr_cassettes/eds/get_with_auth.yml +144 -153
  51. data/test/vcr_cassettes/eds/get_with_auth_recovers_from_bad_auth.yml +167 -223
  52. data/test/view/atom_results_test.rb +94 -94
  53. metadata +36 -46
  54. data/app/assets/javascripts/bento_search.js +0 -3
  55. data/app/item_decorators/bento_search/ebscohost/conditional_openurl_main_link.rb +0 -36
  56. data/app/item_decorators/bento_search/only_premade_openurl.rb +0 -20
  57. data/app/item_decorators/bento_search/openurl_add_other_link.rb +0 -39
  58. data/app/item_decorators/bento_search/openurl_main_link.rb +0 -34
  59. data/app/models/bento_search/multi_searcher.rb +0 -131
  60. data/test/dummy/config/initializers/secret_token.rb +0 -8
  61. data/test/unit/multi_searcher_test.rb +0 -49
@@ -0,0 +1,75 @@
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+ require 'test_helper'
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+
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+ # Doesn't really test the concurrency, but basic smoke test with fake
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+ # searchers.
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+ class ConcurrentSearcherTest < ActiveSupport::TestCase
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+ setup do
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+ BentoSearch.register_engine("one") do |conf|
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+ conf.engine = "MockEngine"
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+ end
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+ BentoSearch.register_engine("two") do |conf|
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+ conf.engine = "MockEngine"
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+ end
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+ BentoSearch.register_engine("three") do |conf|
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+ conf.engine = "MockEngine"
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+ end
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+
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+ BentoSearch.register_engine("raiser") do |conf|
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+ conf.engine = "MockEngine"
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+ conf.raise_exception_class = "StandardError"
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+ end
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+ end
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+
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+ teardown do
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+ BentoSearch.reset_engine_registrations!
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+ end
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+
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+
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+ def test_concurrent_search
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+ searcher = BentoSearch::ConcurrentSearcher.new(:one, :two, :three)
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+ returnval = searcher.search("cancer")
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+
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+ assert_same searcher, returnval
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+
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+ results = searcher.results
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+
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+ assert_kind_of Hash, results
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+ assert_equal ["one", "two", "three"].sort, results.keys.sort
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+
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+ ["one", "two", "three"].each do |key|
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+ assert_kind_of BentoSearch::Results, results[key]
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+ end
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+
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+ # call results again, we get the exact same hash back.
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+ new_results = searcher.results
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+ assert_kind_of Hash, new_results
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+ assert( results.equal? new_results )
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+ end
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+
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+ def test_results_before_search
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+ searcher = BentoSearch::ConcurrentSearcher.new(:one, :two, :three)
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+
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+ assert_raises(ArgumentError) do
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+ results = searcher.results
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+ end
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+ end
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+
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+
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+ def test_concurrent_search_uncaught_exception
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+ searcher = BentoSearch::ConcurrentSearcher.new(:one, :raiser, :two)
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+ results = searcher.search("cancer").results
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+
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+ [:one, :two].each do |success_engine_id|
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+ assert( results[success_engine_id.to_s].kind_of?(BentoSearch::Results) )
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+ assert( !results[success_engine_id.to_s].failed? )
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+ end
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+
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+
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+ error_results = results["raiser"]
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+
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+ assert( error_results.kind_of?(BentoSearch::Results) )
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+ assert( error_results.failed? )
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+ assert( error_results.error[:exception].present? )
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+ assert( error_results.engine_id == "raiser" )
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+ end
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+ end
@@ -3,24 +3,24 @@ require 'test_helper'
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  # Test the BentoSearch::Results::Pagination object
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  class PaginationTest < ActiveSupport::TestCase
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  Pagination = BentoSearch::Results::Pagination
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-
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+
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  def test_implicit_page
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  pag = Pagination.new(100, {:per_page => 10})
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-
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+
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  assert_equal 1, pag.current_page
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  assert_equal 1, pag.start_record
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  assert_equal 10, pag.end_record
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  assert pag.first_page?
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  assert ! pag.last_page?
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  assert_equal 100, pag.count_records
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- assert_equal 100, pag.total_count # some kaminari's want it called this instead.
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+ assert_equal 100, pag.total_count # some kaminari's want it called this instead.
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  assert_equal 10, pag.total_pages
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- assert_equal 10, pag.per_page
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+ assert_equal 10, pag.per_page
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  end
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-
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+
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  def test_last_page
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  pag = Pagination.new(100, {:page => 5, :start => 80, :per_page => 20})
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-
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+
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  assert_equal 5, pag.current_page
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  assert_equal 81, pag.start_record
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  assert_equal 80, pag.offset_value
@@ -31,10 +31,10 @@ class PaginationTest < ActiveSupport::TestCase
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  assert_equal 5, pag.total_pages
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  assert_equal 20, pag.per_page
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  end
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-
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+
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  def test_uneven_pages
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  pag = Pagination.new(95, {:page => 10, :start => 90, :per_page => 10})
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-
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+
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  assert_equal 10, pag.current_page
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  assert_equal 91, pag.start_record
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  assert_equal 95, pag.end_record
@@ -44,10 +44,10 @@ class PaginationTest < ActiveSupport::TestCase
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  assert_equal 10, pag.total_pages
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  assert_equal 10, pag.per_page
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  end
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-
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+
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  def test_empty_args
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  pag = Pagination.new(nil, {})
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-
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+
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  assert_equal 1, pag.current_page
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  assert_equal 0, pag.start_record
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  assert_equal 0, pag.end_record
@@ -56,6 +56,6 @@ class PaginationTest < ActiveSupport::TestCase
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  assert_equal 0, pag.count_records
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  assert_equal 0, pag.total_pages
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  end
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-
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-
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+
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+
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  end
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- 2011, Vol. 117, Issue 16 p3630-3640, 11p&lt;i&gt; ref &lt;/i&gt; 62 ref.</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Metastatic
279
- brain tumors represent 20% to 40% of all intracranial neoplasms and are found
280
- most frequently in association with lung &lt;highlight&gt;cancer&lt;/highlight&gt;
281
- (50%) and breast &lt;highlight&gt;cancer&lt;/highlight&gt; (12%). Although
282
- brain metastases occur in &amp;lt;4% of all tumors of the gastrointestinal
283
- (GI) tract, the incidence of GI brain metastasis is rising in part due to
284
- more effective systemic treatments and prolonged survival of patients with
285
- GI &lt;highlight&gt;cancer&lt;/highlight&gt;. Data were collected from 25
286
- studies (11 colorectal, 7 esophageal, 2 gastric, 1 pancreatic, 1 intestinal,
287
- 3 all-inclusive GI tract &lt;highlight&gt;cancer&lt;/highlight&gt;) and 13
288
- case reports (4 pancreatic, 4 gallbladder, and 5 small bowel &lt;highlight&gt;cancer&lt;/highlight&gt;).
289
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290
- 1.2% of esophageal &lt;highlight&gt;cancer&lt;/highlight&gt;, 0.62% of gastric
291
- &lt;highlight&gt;cancer&lt;/highlight&gt;, and 0.33% of pancreatic &lt;highlight&gt;cancer&lt;/highlight&gt;
292
- cases. Surgical resection with whole brain radiation therapy (WBRT) has been
293
- associated with the longest median survival (38.4-262 weeks) compared with
294
- surgery alone (16.4-70.8 weeks), stereotactic radiosurgery (20-38 weeks),
295
- WBRT alone (7.2-16 weeks), or steroids (4-7 weeks). Survival in patients with
296
- brain metastasis from GI &lt;highlight&gt;cancer&lt;/highlight&gt; was found
297
- to be diminished compared with metastases arising from the breast, lung, or
298
- kidney. Prolonged survival and improvement in clinical symptoms has been found
299
- to be best achieved with surgical resection and WBRT. Although early treatment
300
- has been linked to prolonged survival and improved quality of life, brain
301
- metastases represent a late manifestation of GI &lt;highlight&gt;cancers&lt;/highlight&gt;
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- and remain an ominous sign. (English)</Data></Item><Item><Name>Subject</Name><Label>Subjects
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- &lt;searchLink fieldCode="DE" term="%22Cancer+de+la+v%C3%A9sicule+biliaire%22"&gt;Cancer
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- nervioso central&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22P%C3%A1ncreas+patolog%C3%ADa%22"&gt;Páncreas
383
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22V%C3%ADa+biliar+patolog%C3%ADa%22"&gt;Vía
384
- biliar patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Es%C3%B3fago+patolog%C3%ADa%22"&gt;Esófago
385
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Recto+patolog%C3%ADa%22"&gt;Recto
386
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Col%C3%B3n+patolog%C3%ADa%22"&gt;Colón
387
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Sistema+nervioso+patolog%C3%ADa%22"&gt;Sistema
388
- nervioso patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Sistema+nervosio+central+patolog%C3%ADa%22"&gt;Sistema
389
- nervosio central patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
390
- term="%22Enc%C3%A9falo+patolog%C3%ADa%22"&gt;Encéfalo patología&lt;/searchLink&gt;;
391
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer%22"&gt;Cáncer&lt;/searchLink&gt;;
392
- &lt;searchLink fieldCode="DE" term="%22Tumor+maligno%22"&gt;Tumor maligno&lt;/searchLink&gt;;
393
- &lt;searchLink fieldCode="DE" term="%22Intestino+patolog%C3%ADa%22"&gt;Intestino
394
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Est%C3%B3mago+patolog%C3%ADa%22"&gt;Estómago
395
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+digestivo+patolog%C3%ADa%22"&gt;Aparato
396
- digestivo patología&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
397
- term="%22Met%C3%A1stasis+cerebral%22"&gt;Metástasis cerebral&lt;/searchLink&gt;;
398
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+gastrointestinal%22"&gt;Cáncer
399
- gastrointestinal&lt;/searchLink&gt;</Data></Item></Items></Record><Record><ResultId>2</ResultId><Header><DbId>pcl</DbId><DbLabel>PASCAL</DbLabel><An>25539645</An><RelevancyScore>2394</RelevancyScore><AccessLevel
400
- i:nil="true"/><PubType>Academic Journal</PubType></Header><PLink>http://search.ebscohost.com/login.aspx?direct=true&amp;db=pcl&amp;AN=25539645</PLink><ImageInfo
401
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=01433334&amp;title=Carcinogenesis+(New+York.+Print)&amp;volume=33&amp;issue=1&amp;date=20120101&amp;atitle=Functional+FEN1+genetic+variants+contribute+to+risk+of+hepatocellular+carcinoma%2c+esophageal+cancer%2c+gastric+cancer+and+colorectal+cancer&amp;aulast=LI+LIU&amp;spage=119&amp;sid=EBSCO:PASCAL&amp;pid=&lt;authors&gt;LI+LIU&lt;/authors&gt;&lt;ui&gt;25539645&lt;/ui&gt;&lt;date&gt;20120101&lt;/date&gt;&lt;db&gt;PASCAL&lt;/db&gt;</Url><Name>Find
402
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
403
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
404
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
405
- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Functional
406
- FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal
407
- &lt;highlight&gt;cancer&lt;/highlight&gt;, gastric &lt;highlight&gt;cancer&lt;/highlight&gt;
408
- and colorectal &lt;highlight&gt;cancer&lt;/highlight&gt; (English)</Data></Item><Item><Name>Author</Name><Label>Author</Label><Group>Au</Group><Data>&lt;searchLink
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- fieldCode="AR" term="%22LI+LIU%22"&gt;LI LIU&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
410
- &lt;searchLink fieldCode="AR" term="%22CHANGCHUN+ZHOU%22"&gt;CHANGCHUN ZHOU&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;;
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- &lt;searchLink fieldCode="AR" term="%22LIQING+ZHOU%22"&gt;LIQING ZHOU&lt;/searchLink&gt;&lt;relatesTo&gt;b3&lt;/relatesTo&gt;;
412
- &lt;searchLink fieldCode="AR" term="%22LI+PENG%22"&gt;LI PENG&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;;
413
- &lt;searchLink fieldCode="AR" term="%22DAPENG+LI%22"&gt;DAPENG LI&lt;/searchLink&gt;&lt;relatesTo&gt;b4&lt;/relatesTo&gt;;
414
- &lt;searchLink fieldCode="AR" term="%22XIAOJIAO+ZHANG%22"&gt;XIAOJIAO ZHANG&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
415
- &lt;searchLink fieldCode="AR" term="%22MO+ZHOU%22"&gt;MO ZHOU&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
416
- &lt;searchLink fieldCode="AR" term="%22PENGQUN+KUANG%22"&gt;PENGQUN KUANG&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
417
- &lt;searchLink fieldCode="AR" term="%22QIPENG+YUAN%22"&gt;QIPENG YUAN&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
418
- &lt;searchLink fieldCode="AR" term="%22XIANRANG+SONG%22"&gt;XIANRANG SONG&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;;
419
- &lt;searchLink fieldCode="AR" term="%22MING+YANG%22"&gt;MING YANG&lt;/searchLink&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
420
- fieldCode="JN" term="%22Carcinogenesis+%28New+York%2E+Print%29%22"&gt;Carcinogenesis
421
- (New York. Print)&lt;/searchLink&gt; [Carcinogenesis (N. Y., Print)], 2012,
422
- Vol. 33, Issue 1 p119-123, 5p&lt;i&gt; ref &lt;/i&gt; 14 ref.</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>As
423
- a DNA repair protein, Flap endonuclease 1 (FEN1) plays crucial parts in preventing
424
- carcinogenesis. Two functional germ line variants (―69G &amp;gt; A and 4150G
425
- &amp;gt; T) in the FEN1 gene have been associated with DNA damage levels in
426
- coke oven workers and lung &lt;highlight&gt;cancer&lt;/highlight&gt; risk
427
- in general populations. However, the role of these genetic variants on gastrointestinal
428
- &lt;highlight&gt;cancer&lt;/highlight&gt; susceptibility is unknown. Therefore,
429
- we evaluated the association between these polymorphisms and gastrointestinal
430
- &lt;highlight&gt;cancer&lt;/highlight&gt; risk in two independent case― control
431
- cohorts consisted of a total of 1850 gastrointestinal &lt;highlight&gt;cancer&lt;/highlight&gt;
432
- (hepatocellular carcinoma, esophageal &lt;highlight&gt;cancer&lt;/highlight&gt;,
433
- gastric &lt;highlight&gt;cancer&lt;/highlight&gt; and colorectal &lt;highlight&gt;cancer&lt;/highlight&gt;)
434
- patients and 2222 healthy controls. The impact of these variations on FEN1
435
- expression was also examined using liver, esophagus, stomach and colon normal
436
- tissues. It was found that the FEN1 ―69GG genotypes were significantly correlated
437
- to increased risk for developing gastrointestinal &lt;highlight&gt;cancer&lt;/highlight&gt;
438
- compared with the ―69AA genotype in both cohorts [Jinan cohort: odds ratios
439
- (OR) = 2.14, 95% confidence interval (CI) = 1.47―2.80, P = 1.0 × 10[sub]―6[/sub];
440
- Huaian cohort: OR = 1.93, 95% CI = 1.37―2.50, P = 0.5 × 10[sub]―6[/sub]].
441
- Similar results were observed for 4150G &amp;gt; T polymorphism. In the combined
442
- meta-analyses, OR for ―69GG or 4150GG genotype was 2.02 (95% CI = 1.59―2.45)
443
- or 1.86 (95% CI = 1.45―2.28) compared with ―69AA or 4150TT genotype. In vivo
444
- FEN1 messenger RNA expression analyses showed that the ―69G or 4150G allele
445
- carriers had ∼2-fold decreased FEN1 expression in gastrointestinal tissues
446
- compared with ―69A or 4150T carriers, indicating that lower FEN1 expression
447
- may lead to higher risk for malignant transformation of gastrointestinal cells.
448
- Our results highlight FEN1 as an important gene in human gastrointestinal
449
- oncogenesis and genetic polymorphisms in FEN1 confer susceptibility to gastrointestinal
450
- &lt;highlight&gt;cancers&lt;/highlight&gt;. (English)</Data></Item><Item><Name>Subject</Name><Label>Subjects
451
- (French)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Cancer+de+lestomac%22"&gt;Cancer
452
- de lestomac&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+de+loesophage%22"&gt;Cancer
453
- de loesophage&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+du+foie%22"&gt;Cancer
454
- du foie&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+colorectal%22"&gt;Cancer
455
- colorectal&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Carcinome+h%C3%A9patocellulaire%22"&gt;Carcinome
456
- hépatocellulaire&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Facteur+risque%22"&gt;Facteur
457
- risque&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Variant+g%C3%A9n%C3%A9tique%22"&gt;Variant
458
- génétique&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Pathologie+du+rectum%22"&gt;Pathologie
459
- du rectum&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lintestin%22"&gt;Pathologie
460
- de lintestin&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+du+c%C3%B4lon%22"&gt;Pathologie
461
- du côlon&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lestomac%22"&gt;Pathologie
462
- de lestomac&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+loesophage%22"&gt;Pathologie
463
- de loesophage&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
464
- &lt;searchLink fieldCode="DE" term="%22Tumeur+maligne%22"&gt;Tumeur maligne&lt;/searchLink&gt;;
465
- &lt;searchLink fieldCode="DE" term="%22Pathologie+du+foie%22"&gt;Pathologie
466
- du foie&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+digestif%22"&gt;Pathologie
467
- de lappareil digestif&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
468
- (English)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Stomach+cancer%22"&gt;Stomach
469
- cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Esophagus+cancer%22"&gt;Esophagus
470
- cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Liver+cancer%22"&gt;Liver
471
- cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Colorectal+cancer%22"&gt;Colorectal
472
- cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Hepatocellular+carcinoma%22"&gt;Hepatocellular
473
- carcinoma&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Risk+factor%22"&gt;Risk
474
- factor&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Genetic+variant%22"&gt;Genetic
475
- variant&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Rectal+disease%22"&gt;Rectal
476
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Intestinal+disease%22"&gt;Intestinal
477
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Colonic+disease%22"&gt;Colonic
478
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Gastric+disease%22"&gt;Gastric
479
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Esophageal+disease%22"&gt;Esophageal
480
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
481
- &lt;searchLink fieldCode="DE" term="%22Malignant+tumor%22"&gt;Malignant tumor&lt;/searchLink&gt;;
482
- &lt;searchLink fieldCode="DE" term="%22Hepatic+disease%22"&gt;Hepatic disease&lt;/searchLink&gt;;
483
- &lt;searchLink fieldCode="DE" term="%22Digestive+diseases%22"&gt;Digestive
484
- diseases&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
485
- (Spanish)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+est%C3%B3mago%22"&gt;Cáncer
486
- del estómago&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+es%C3%B3fago%22"&gt;Cáncer
487
- del esófago&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+h%C3%ADgado%22"&gt;Cáncer
488
- del hígado&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+de+colon+y+recto%22"&gt;Cancer
489
- de colon y recto&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Carcinoma+hepatocelular%22"&gt;Carcinoma
490
- hepatocelular&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Factor+riesgo%22"&gt;Factor
491
- riesgo&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Variante+gen%C3%A9tica%22"&gt;Variante
492
- genética&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Recto+patolog%C3%ADa%22"&gt;Recto
493
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Intestino+patolog%C3%ADa%22"&gt;Intestino
494
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Col%C3%B3n+patolog%C3%ADa%22"&gt;Colón
495
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Est%C3%B3mago+patolog%C3%ADa%22"&gt;Estómago
496
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Es%C3%B3fago+patolog%C3%ADa%22"&gt;Esófago
497
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer%22"&gt;Cáncer&lt;/searchLink&gt;;
498
- &lt;searchLink fieldCode="DE" term="%22Tumor+maligno%22"&gt;Tumor maligno&lt;/searchLink&gt;;
499
- &lt;searchLink fieldCode="DE" term="%22H%C3%ADgado+patolog%C3%ADa%22"&gt;Hígado
500
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+digestivo+patolog%C3%ADa%22"&gt;Aparato
501
- digestivo patología&lt;/searchLink&gt;</Data></Item></Items></Record><Record><ResultId>3</ResultId><Header><DbId>edsihc</DbId><DbLabel>Informit
502
- Health Collection</DbLabel><An>535749118010911</An><RelevancyScore>2389</RelevancyScore><AccessLevel
503
- i:nil="true"/><PubType>Academic Journal</PubType></Header><PLink>http://search.ebscohost.com/login.aspx?direct=true&amp;db=edsihc&amp;AN=535749118010911</PLink><ImageInfo
504
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=14485028&amp;title=Sexual+Health&amp;volume=8&amp;issue=4&amp;date=20111201&amp;atitle=HIV%2c+cancer%2c+and+aging.&amp;aulast=Grulich%2c+Andrew+E&amp;spage=521&amp;sid=EBSCO:Informit+Health+Collection&amp;pid=&lt;authors&gt;Grulich%2c+Andrew+E&lt;/authors&gt;&lt;ui&gt;535749118010911&lt;/ui&gt;&lt;date&gt;20111201&lt;/date&gt;&lt;db&gt;Informit+Health+Collection&lt;/db&gt;</Url><Name>Find
505
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
506
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
507
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
508
- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>HIV,
509
- &lt;highlight&gt;cancer&lt;/highlight&gt;, and aging.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
510
- fieldCode="AR" term="%22Grulich%2C+Andrew+E%22"&gt;Grulich, Andrew E&lt;/searchLink&gt;&lt;br
511
- /&gt;&lt;searchLink fieldCode="AR" term="%22Jin%2C+Fengyi%22"&gt;Jin, Fengyi&lt;/searchLink&gt;&lt;br
512
- /&gt;&lt;searchLink fieldCode="AR" term="%22Poynten%2C+IMary%22"&gt;Poynten,
513
- IMary&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22Vajdic%2C+Claire+M%22"&gt;Vajdic,
514
- Claire M&lt;/searchLink&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>Sexual
515
- Health, Vol. 8, No. 4, Dec 2011: 521-525.</Data></Item><Item><Name>Subject</Name><Label>Subjects</Label><Group>Su</Group><Data>&lt;searchLink
516
- fieldCode="DE" term="%22AIDS+%28Disease%29+in+old+age%22"&gt;AIDS (Disease)
517
- in old age&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Cancer+--+Risk+factors%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
518
- -- Risk factors&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
519
- term="%22Immunological+deficiency+syndromes%22"&gt;Immunological deficiency
520
- syndromes&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Cancer+--+Prevention%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
521
- -- Prevention&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
522
- term="%22Papillomavirus+diseases%22"&gt;Papillomavirus diseases&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>As
523
- people with HIV age, they will experience increasing rates of all diseases
524
- of aging, including &lt;highlight&gt;cancer&lt;/highlight&gt;. However, the
525
- pattern of higher &lt;highlight&gt;cancer&lt;/highlight&gt; risk in people
526
- with HIV is mostly explained by the chronic effects of certain oncogenic infections,
527
- and is not consistent with a syndrome of accelerated aging. Many of those
528
- cancers that are most closely associated with aging do not occur at increased
529
- rates in people with HIV compared with the general population. The risk of
530
- many infection-associated cancers in people with HIV is closely related to
531
- the degree of immune deficiency, and for some types of &lt;highlight&gt;cancer&lt;/highlight&gt;,
532
- it is also associated with ongoing HIV replication. Thus, if HIV therapy can
533
- provide durable HIV suppression and maintain near normal levels of immune
534
- function, the excess risk of &lt;highlight&gt;cancer&lt;/highlight&gt; is
535
- likely to be minimised. While avoidance of profound immunity will greatly
536
- reduce &lt;highlight&gt;cancer&lt;/highlight&gt; risk, it is unclear how close
537
- to normal immune function must be to minimise HIV-associated &lt;highlight&gt;cancer&lt;/highlight&gt;
538
- risk. People with HIV are also at a high risk of &lt;highlight&gt;cancer&lt;/highlight&gt;
539
- because they have high rates of lifestyle risks for &lt;highlight&gt;cancer&lt;/highlight&gt;,
540
- in particular tobacco and alcohol exposure. For most cancers, it is appropriate
541
- to follow general population guidelines on &lt;highlight&gt;cancer&lt;/highlight&gt;
542
- screening. The exception is cervical &lt;highlight&gt;cancer&lt;/highlight&gt;,
543
- for which annual screening is recommended. In addition, active research is
544
- required to establish whether anal &lt;highlight&gt;cancer&lt;/highlight&gt;
545
- screening would prevent the unacceptably high levels of morbidity caused by
546
- this disease in people with HIV, most particularly in gay men.</Data></Item></Items></Record><Record><ResultId>4</ResultId><Header><DbId>pcl</DbId><DbLabel>PASCAL</DbLabel><An>23742280</An><RelevancyScore>2379</RelevancyScore><AccessLevel
547
- i:nil="true"/><PubType/></Header><PLink>http://search.ebscohost.com/login.aspx?direct=true&amp;db=pcl&amp;AN=23742280</PLink><ImageInfo
548
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=00074551&amp;title=Bulletin+du+cancer&amp;volume=98&amp;issue=1&amp;date=20110101&amp;atitle=&amp;aulast=&amp;spage=&amp;sid=EBSCO:PASCAL&amp;pid=&lt;authors&gt;&lt;/authors&gt;&lt;ui&gt;23742280&lt;/ui&gt;&lt;date&gt;20110101&lt;/date&gt;&lt;db&gt;PASCAL&lt;/db&gt;</Url><Name>Find
549
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
550
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
551
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
552
- i:nil="true"/></FullText><Items><Item><Name>TitleBook</Name><Label>Title (monograph)</Label><Group>Ti</Group><Data>La
553
- chirurgie d''après (French)</Data></Item><Item><Name>AuthorEditor</Name><Label>Editor</Label><Group>Au</Group><Data>&lt;searchLink
554
- fieldCode="AR" term="%22EVRARD%2C+Serge%22"&gt;EVRARD, Serge&lt;/searchLink&gt;&lt;relatesTo&gt;a1&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
555
- fieldCode="JN" term="%22Bulletin+du+cancer%22"&gt;Bulletin du cancer&lt;/searchLink&gt;
556
- [Bull. &lt;highlight&gt;cancer&lt;/highlight&gt;], 2011, Vol. 98, Issue 1,
557
- 80p&lt;i&gt; ref &lt;/i&gt; dissem.</Data></Item><Item><Name>Subject</Name><Label>Subjects
558
- (French)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Homme%22"&gt;Homme&lt;/searchLink&gt;;
559
- &lt;searchLink fieldCode="DE" term="%22Traitement+associ%C3%A9%22"&gt;Traitement
560
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- Title</Label><Group>Ti</Group><Data>Actualités Chicago 2011 : Rapport d''experts
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- (French)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Homme%22"&gt;Homme&lt;/searchLink&gt;;
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685
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687
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688
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689
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- &lt;searchLink fieldCode="DE" term="%22Cancer+de+la+prostate%22"&gt;Cancer
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694
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695
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- &lt;searchLink fieldCode="DE" term="%22Cancer+rein%22"&gt;Cancer rein&lt;/searchLink&gt;&lt;br
697
- /&gt;&lt;searchLink fieldCode="DE" term="%22Pathologie+des+bronches%22"&gt;Pathologie
698
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699
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700
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701
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703
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707
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708
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711
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714
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725
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731
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733
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734
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735
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Lung+disease%22"&gt;Lung
736
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Respiratory+disease%22"&gt;Respiratory
737
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pancreatic+disease%22"&gt;Pancreatic
738
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Gastric+disease%22"&gt;Gastric
739
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Hepatic+disease%22"&gt;Hepatic
740
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Rectal+disease%22"&gt;Rectal
741
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Colonic+disease%22"&gt;Colonic
742
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Intestinal+disease%22"&gt;Intestinal
743
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Digestive+diseases%22"&gt;Digestive
744
- diseases&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Breast+disease%22"&gt;Breast
745
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Mammary+gland+diseases%22"&gt;Mammary
746
- gland diseases&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Male+genital+diseases%22"&gt;Male
747
- genital diseases&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Prostate+disease%22"&gt;Prostate
748
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Kidney+disease%22"&gt;Kidney
749
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Urinary+system+disease%22"&gt;Urinary
750
- system disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Malignant+tumor%22"&gt;Malignant
751
- tumor&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
752
- (Spanish)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Hombre%22"&gt;Hombre&lt;/searchLink&gt;;
753
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+pulm%C3%B3n%22"&gt;Cáncer
754
- del pulmón&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+p%C3%A1ncreas%22"&gt;Cáncer
755
- del páncreas&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Ensayo+cl%C3%ADnico+fase+III%22"&gt;Ensayo
756
- clínico fase III&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+de+colon+y+recto%22"&gt;Cancer
757
- de colon y recto&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Ensayo+cl%C3%ADnico+fase+II%22"&gt;Ensayo
758
- clínico fase II&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+est%C3%B3mago%22"&gt;Cáncer
759
- del estómago&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+pecho%22"&gt;Cáncer
760
- del pecho&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+h%C3%ADgado%22"&gt;Cáncer
761
- del hígado&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Tratamiento%22"&gt;Tratamiento&lt;/searchLink&gt;;
762
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+de+la+pr%C3%B3stata%22"&gt;Cáncer
763
- de la próstata&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Recaida%22"&gt;Recaida&lt;/searchLink&gt;;
764
- &lt;searchLink fieldCode="DE" term="%22Nefrolog%C3%ADa%22"&gt;Nefrología&lt;/searchLink&gt;;
765
- &lt;searchLink fieldCode="DE" term="%22Hemopat%C3%ADa+maligna%22"&gt;Hemopatía
766
- maligna&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Urolog%C3%ADa%22"&gt;Urología&lt;/searchLink&gt;;
767
- &lt;searchLink fieldCode="DE" term="%22Cancerolog%C3%ADa%22"&gt;Cancerología&lt;/searchLink&gt;;
768
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+ri%C3%B1%C3%B3n%22"&gt;Cáncer
769
- del riñón&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Bronquio+patolog%C3%ADa%22"&gt;Bronquio
770
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pulm%C3%B3n+patolog%C3%ADa%22"&gt;Pulmón
771
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+respiratorio+patolog%C3%ADa%22"&gt;Aparato
772
- respiratorio patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22P%C3%A1ncreas+patolog%C3%ADa%22"&gt;Páncreas
773
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Est%C3%B3mago+patolog%C3%ADa%22"&gt;Estómago
774
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22H%C3%ADgado+patolog%C3%ADa%22"&gt;Hígado
775
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Recto+patolog%C3%ADa%22"&gt;Recto
776
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Col%C3%B3n+patolog%C3%ADa%22"&gt;Colón
777
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Intestino+patolog%C3%ADa%22"&gt;Intestino
778
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+digestivo+patolog%C3%ADa%22"&gt;Aparato
779
- digestivo patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Seno+patolog%C3%ADa%22"&gt;Seno
780
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Gl%C3%A1ndula+mamaria+patolog%C3%ADa%22"&gt;Glándula
781
- mamaria patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+genital+macho+patolog%C3%ADa%22"&gt;Aparato
782
- genital macho patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
783
- term="%22Prostata+patolog%C3%ADa%22"&gt;Prostata patología&lt;/searchLink&gt;;
784
- &lt;searchLink fieldCode="DE" term="%22Ri%C3%B1%C3%B3n+patolog%C3%ADa%22"&gt;Riñón
785
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+urinario+patolog%C3%ADa%22"&gt;Aparato
786
- urinario patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Tumor+maligno%22"&gt;Tumor
787
- maligno&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer%22"&gt;Cáncer&lt;/searchLink&gt;</Data></Item></Items></Record><Record><ResultId>6</ResultId><Header><DbId>edsihc</DbId><DbLabel>Informit
788
- Health Collection</DbLabel><An>506532619078053</An><RelevancyScore>2378</RelevancyScore><AccessLevel
789
- i:nil="true"/><PubType>Academic Journal</PubType></Header><PLink>http://search.ebscohost.com/login.aspx?direct=true&amp;db=edsihc&amp;AN=506532619078053</PLink><ImageInfo
790
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=0311306X&amp;title=Cancer+Forum&amp;volume=35&amp;issue=3&amp;date=20111101&amp;atitle=Cancer+research+and+funding+in+Western+Australia%3a+An+overview+from+2008+to+2010.&amp;aulast=Shirazee%2c+Nicole&amp;spage=183&amp;sid=EBSCO:Informit+Health+Collection&amp;pid=&lt;authors&gt;Shirazee%2c+Nicole&lt;/authors&gt;&lt;ui&gt;506532619078053&lt;/ui&gt;&lt;date&gt;20111101&lt;/date&gt;&lt;db&gt;Informit+Health+Collection&lt;/db&gt;</Url><Name>Find
791
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
792
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
793
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
794
- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>&lt;highlight&gt;Cancer&lt;/highlight&gt;
795
- research and funding in Western Australia: An overview from 2008 to 2010.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
796
- fieldCode="AR" term="%22Shirazee%2C+Nicole%22"&gt;Shirazee, Nicole&lt;/searchLink&gt;&lt;br
797
- /&gt;&lt;searchLink fieldCode="AR" term="%22Musiello%2C+Toni%22"&gt;Musiello,
798
- Toni&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22Johnson%2C+Claire%22"&gt;Johnson,
799
- Claire&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22Saunders%2C+Christobel%22"&gt;Saunders,
800
- Christobel&lt;/searchLink&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;highlight&gt;Cancer&lt;/highlight&gt;
801
- Forum, Vol. 35, No. 3, Nov 2011: 183-188.</Data></Item><Item><Name>Subject</Name><Label>Subjects</Label><Group>Su</Group><Data>&lt;searchLink
802
- fieldCode="DE" term="%22Cancer+--+Research+grants%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
803
- -- Research grants&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
804
- term="%22Cancer+--+Patients+--+Care%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
805
- -- Patients -- Care&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
806
- term="%22Cancer+--+Treatment%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
807
- -- Treatment&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Cancer+--+Patients+--+Services+for%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
808
- -- Patients -- Services for&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
809
- term="%22Cancer+--+Diagnosis+--+Australia%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
810
- -- Diagnosis -- Australia&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Funding
811
- for &lt;highlight&gt;cancer&lt;/highlight&gt; research plays a vital role
812
- in improving all aspects of &lt;highlight&gt;cancer&lt;/highlight&gt; care
813
- and, thus, cancer-related outcomes. To identify strengths and gaps in current
814
- &lt;highlight&gt;cancer&lt;/highlight&gt; research activities in Western Australia,
815
- an audit of all competitive funding for &lt;highlight&gt;cancer&lt;/highlight&gt;
816
- research undertaken in Western Australia during 2008-2010 was conducted. The
817
- Commonwealth Government was identified as the most significant contributor
818
- to competitive &lt;highlight&gt;cancer&lt;/highlight&gt; research funding,
819
- however the amount received by Western Australian researchers was much less
820
- than by other states such as New South Wales and Victoria. These states also
821
- attract larger amounts of international funding. The broad research areas
822
- that received the most funding were biology and treatment. Most &lt;highlight&gt;cancer&lt;/highlight&gt;
823
- research projects focused on multiple tumour sites or were basic science projects.
824
- Relative to their burden of disease, some tumour types such as liver, oesophageal,
825
- ovarian and pancreatic &lt;highlight&gt;cancer&lt;/highlight&gt; may be underfunded.
826
- To increase the success of Western Australian &lt;highlight&gt;cancer&lt;/highlight&gt;
827
- researchers at a national and international level, support and capacity building
828
- is needed at a local level. Identified research priorities with targeted support
829
- should be integrated into &lt;highlight&gt;cancer&lt;/highlight&gt; planning
830
- to ensure the development of research capacity in areas of most need.</Data></Item></Items></Record><Record><ResultId>7</ResultId><Header><DbId>pcl</DbId><DbLabel>PASCAL</DbLabel><An>25600338</An><RelevancyScore>2377</RelevancyScore><AccessLevel
831
- i:nil="true"/><PubType>Academic Journal</PubType></Header><PLink>http://search.ebscohost.com/login.aspx?direct=true&amp;db=pcl&amp;AN=25600338</PLink><ImageInfo
832
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=00165107&amp;title=Gastrointestinal+endoscopy+(Print)&amp;volume=75&amp;issue=3&amp;date=20120101&amp;atitle=Colorectal+cancers+not+detected+by+screening+flexible+sigmoidoscopy+in+the+Prostate%2c+Lung%2c+Colorectal%2c+and+Ovarian+Cancer+Screening+Trial&amp;aulast=SCHOEN%2c+Robert+E.&amp;spage=612&amp;sid=EBSCO:PASCAL&amp;pid=&lt;authors&gt;SCHOEN%2c+Robert+E.&lt;/authors&gt;&lt;ui&gt;25600338&lt;/ui&gt;&lt;date&gt;20120101&lt;/date&gt;&lt;db&gt;PASCAL&lt;/db&gt;</Url><Name>Find
833
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
834
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
835
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
836
- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Colorectal
837
- &lt;highlight&gt;cancers&lt;/highlight&gt; not detected by screening flexible
838
- sigmoidoscopy in the Prostate, Lung, Colorectal, and Ovarian &lt;highlight&gt;Cancer&lt;/highlight&gt;
839
- Screening Trial (English)</Data></Item><Item><Name>Author</Name><Label>Author</Label><Group>Au</Group><Data>&lt;searchLink
840
- fieldCode="AR" term="%22SCHOEN%2C+Robert+E%2E%22"&gt;SCHOEN, Robert E.&lt;/searchLink&gt;&lt;relatesTo&gt;b1
841
- b2&lt;/relatesTo&gt;; &lt;searchLink fieldCode="AR" term="%22PINSKY%2C+Paul+F%2E%22"&gt;PINSKY,
842
- Paul F.&lt;/searchLink&gt;&lt;relatesTo&gt;b3&lt;/relatesTo&gt;; &lt;searchLink
843
- fieldCode="AR" term="%22WEISSFELD%2C+Joel+L%2E%22"&gt;WEISSFELD, Joel L.&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;;
844
- &lt;searchLink fieldCode="AR" term="%22YOKOCHI%2C+Lance+A%2E%22"&gt;YOKOCHI,
845
- Lance A.&lt;/searchLink&gt;&lt;relatesTo&gt;b4&lt;/relatesTo&gt;; &lt;searchLink
846
- fieldCode="AR" term="%22CHURCH%2C+Timothy%22"&gt;CHURCH, Timothy&lt;/searchLink&gt;&lt;relatesTo&gt;b5&lt;/relatesTo&gt;;
847
- &lt;searchLink fieldCode="AR" term="%22LAIYEMO%2C+Adeyinka+O%2E%22"&gt;LAIYEMO,
848
- Adeyinka O.&lt;/searchLink&gt;&lt;relatesTo&gt;b6&lt;/relatesTo&gt;; &lt;searchLink
849
- fieldCode="AR" term="%22BRESALIER%2C+Robert%22"&gt;BRESALIER, Robert&lt;/searchLink&gt;&lt;relatesTo&gt;b7&lt;/relatesTo&gt;;
850
- &lt;searchLink fieldCode="AR" term="%22HICKEY%2C+Tom%22"&gt;HICKEY, Tom&lt;/searchLink&gt;&lt;relatesTo&gt;b8&lt;/relatesTo&gt;;
851
- &lt;searchLink fieldCode="AR" term="%22RILEY%2C+Thomas%22"&gt;RILEY, Thomas&lt;/searchLink&gt;&lt;relatesTo&gt;b8&lt;/relatesTo&gt;;
852
- &lt;searchLink fieldCode="AR" term="%22PROROK%2C+Philip+C%2E%22"&gt;PROROK,
853
- Philip C.&lt;/searchLink&gt;&lt;relatesTo&gt;b3&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
854
- fieldCode="JN" term="%22Gastrointestinal+endoscopy+%28Print%29%22"&gt;Gastrointestinal
855
- endoscopy (Print)&lt;/searchLink&gt; [Gastrointest. endosc. (Print)], 2012,
856
- Vol. 75, Issue 3 p612-620, 9p&lt;i&gt; ref &lt;/i&gt; 35 ref.</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Background
857
- and Objective: Diagnosis of colorectal &lt;highlight&gt;cancer&lt;/highlight&gt;
858
- after negative findings on endoscopic evaluation raises concern about the
859
- effectiveness of endoscopic screening. We contrast screening-detected &lt;highlight&gt;cancers&lt;/highlight&gt;
860
- with &lt;highlight&gt;cancers&lt;/highlight&gt; not detected by screening
861
- among participants assigned to flexible sigmoidoscopy (FSG) in the Prostate,
862
- Lung, Colorectal, and Ovarian (PLCO) &lt;highlight&gt;Cancer&lt;/highlight&gt;
863
- Screening Trial to determine the reasons for the lack of detection of prevalent
864
- lesions. Design: &lt;highlight&gt;Cancers&lt;/highlight&gt; detected within
865
- 1 year of a screening FSG with abnormal findings were classified as screening
866
- detected. All other &lt;highlight&gt;cancers&lt;/highlight&gt; were categorized,
867
- based on &lt;highlight&gt;cancer&lt;/highlight&gt; stage and years until detection,
868
- as either not detectable or prevalent but not detected at the time of screening.
869
- Setting/Patients: A total of 77,447 subjects in the multicenter PLCO trial.
870
- Main Outcome Measurements: A total of 977 colorectal &lt;highlight&gt;cancers&lt;/highlight&gt;
871
- were diagnosed with a mean follow-up of 11.5 years. Results: A total of 243
872
- (24.9%) &lt;highlight&gt;cancers&lt;/highlight&gt; were screening detected,
873
- 470 (48.1%) were not detectable at screening, and 264 (27.0%) were considered
874
- prevalent but not detected. Among prevalent nondetected lesions, 35.6% (n
875
- = 94) were attributed to problems in patient compliance (58 never screened,
876
- 34 delayed colonoscopy follow-up, and 2 inadequate bowel preparation), 43.9%
877
- (n = 116) were attributable to a limitation in the FSG procedure (97 beyond
878
- the reach of the sigmoidoscope and 19 inadequate depth of insertion on FSG),
879
- and 20.5% (n = 54) were caused by endoscopist limitation (33 missed on FSG,
880
- 21 missed at initial colonoscopy) (P &amp;lt; .0001). Had colonoscopy instead
881
- of FSG been used for screening, an additional 15.6% and as many as 19.0% of
882
- &lt;highlight&gt;cancers&lt;/highlight&gt; may have been screening-detected.
883
- Limitations: These estimates are reasonable approximations, but biological
884
- variability precludes precise determinations. Conclusions: Prevalent nondetected
885
- &lt;highlight&gt;cancers&lt;/highlight&gt; were more often attributable to
886
- problems with patient compliance or limitations in the FSG procedure than
887
- to missed lesions. Colonoscopy instead of FSG could have moderately increased
888
- the detection ot &lt;highlight&gt;cancer&lt;/highlight&gt; via screening.
889
- (English)</Data></Item><Item><Name>Subject</Name><Label>Subjects (French)</Label><Group>Su</Group><Data>&lt;searchLink
890
- fieldCode="DE" term="%22C%C3%B4lon%22"&gt;Côlon&lt;/searchLink&gt;; &lt;searchLink
891
- fieldCode="DE" term="%22Cancer+de+lovaire%22"&gt;Cancer de lovaire&lt;/searchLink&gt;;
892
- &lt;searchLink fieldCode="DE" term="%22Sigmo%C3%AFdoscopie%22"&gt;Sigmoïdoscopie&lt;/searchLink&gt;;
893
- &lt;searchLink fieldCode="DE" term="%22Flexible%22"&gt;Flexible&lt;/searchLink&gt;;
894
- &lt;searchLink fieldCode="DE" term="%22D%C3%A9pistage%22"&gt;Dépistage&lt;/searchLink&gt;;
895
- &lt;searchLink fieldCode="DE" term="%22Cancer+du+poumon%22"&gt;Cancer du poumon&lt;/searchLink&gt;;
896
- &lt;searchLink fieldCode="DE" term="%22Cancer+de+la+prostate%22"&gt;Cancer
897
- de la prostate&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+colorectal%22"&gt;Cancer
898
- colorectal&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Pathologie+des+ovaires%22"&gt;Pathologie
899
- des ovaires&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+g%C3%A9nital+femelle%22"&gt;Pathologie
900
- de lappareil génital femelle&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
901
- term="%22Pathologie+des+poumons%22"&gt;Pathologie des poumons&lt;/searchLink&gt;;
902
- &lt;searchLink fieldCode="DE" term="%22Pathologie+des+bronches%22"&gt;Pathologie
903
- des bronches&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+respiratoire%22"&gt;Pathologie
904
- de lappareil respiratoire&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
905
- term="%22Pathologie+de+la+prostate%22"&gt;Pathologie de la prostate&lt;/searchLink&gt;;
906
- &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+urinaire%22"&gt;Pathologie
907
- de lappareil urinaire&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+g%C3%A9nital+m%C3%A2le%22"&gt;Pathologie
908
- de lappareil génital mâle&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
909
- term="%22Pathologie+du+rectum%22"&gt;Pathologie du rectum&lt;/searchLink&gt;;
910
- &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
911
- &lt;searchLink fieldCode="DE" term="%22Tumeur+maligne%22"&gt;Tumeur maligne&lt;/searchLink&gt;;
912
- &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lintestin%22"&gt;Pathologie
913
- de lintestin&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+du+c%C3%B4lon%22"&gt;Pathologie
914
- du côlon&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+digestif%22"&gt;Pathologie
915
- de lappareil digestif&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
916
- term="%22Endoscopie+gastrointestinale%22"&gt;Endoscopie gastrointestinale&lt;/searchLink&gt;&lt;br
917
- /&gt;&lt;searchLink fieldCode="DE" term="%22Endoscopie+digestive%22"&gt;Endoscopie
918
- digestive&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
919
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921
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923
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925
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926
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927
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928
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929
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930
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931
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932
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934
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935
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936
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939
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940
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Digestive+diseases%22"&gt;Digestive
941
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942
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948
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949
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950
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- &lt;searchLink fieldCode="DE" term="%22Aparato+genital+hembra+patolog%C3%ADa%22"&gt;Aparato
953
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- term="%22Pulm%C3%B3n+patolog%C3%ADa%22"&gt;Pulmón patología&lt;/searchLink&gt;;
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956
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957
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958
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960
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965
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- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Épidémiologie
974
- des &lt;highlight&gt;cancers&lt;/highlight&gt; urologiques au Centre national
975
- hospitalier universitaire Hubert Koutoukou Maga Cotonou, Bénin. Analyse d''une
976
- série hospitalière de 158 cas (French)</Data></Item><Item><Name>TitleAlt</Name><Label>Other
977
- Title</Label><Group>Ti</Group><Data>Epidemiology of urologic &lt;highlight&gt;cancers&lt;/highlight&gt;
978
- in university teaching hospital of Cotonou, Benin. Review about 158 cases
979
- of urologic &lt;highlight&gt;cancers&lt;/highlight&gt; (English)</Data></Item><Item><Name>Author</Name><Label>Author</Label><Group>Au</Group><Data>&lt;searchLink
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- fieldCode="AR" term="%22OUATTARA%2C+A%2E%22"&gt;OUATTARA, A.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
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- &lt;searchLink fieldCode="AR" term="%22AVAKOUDJO%2C+J%2E%22"&gt;AVAKOUDJO,
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- J.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;; &lt;searchLink
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- fieldCode="AR" term="%22CISSE%2C+D%2E%22"&gt;CISSE, D.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
985
- &lt;searchLink fieldCode="AR" term="%22ZANGO%2C+B%2E%22"&gt;ZANGO, B.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
986
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- F. D. J. M.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;; &lt;searchLink
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990
- &lt;searchLink fieldCode="AR" term="%22VODONOU%2C+A%2E%22"&gt;VODONOU, A.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
991
- &lt;searchLink fieldCode="AR" term="%22HOUNNASSO%2C+P%2E+P%2E%22"&gt;HOUNNASSO,
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- P. P.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;; &lt;searchLink
993
- fieldCode="AR" term="%22AKPO%2C+C%2E+E%2E%22"&gt;AKPO, C. E.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
994
- fieldCode="JN" term="%22Progr%C3%A8s+en+urologie+%28Paris%29%22"&gt;Progrès
995
- en urologie (Paris)&lt;/searchLink&gt; [Prog. urol. (Paris)], 2012, Vol. 22,
996
- Issue 5 p261-265, 5p&lt;i&gt; ref &lt;/i&gt; 11 ref.</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>But.
997
- - Étudier le profil épidémiologique des &lt;highlight&gt;cancers&lt;/highlight&gt;
998
- urologiques à la clinique universitaire d''urologie-andrologie du CNHU-HKM
999
- de Cotonou. Matériel et méthodes. - Il s''est agi d''une étude descriptive
1000
- rétrospective allant du 1[sub]er[/sub] janvier 2008 au 30 juin 2011. Tous
1001
- les cas de &lt;highlight&gt;cancer&lt;/highlight&gt; urologique admis dans
1002
- le service ont été analysés en s''intéressant à la localisation anatomique
1003
- du &lt;highlight&gt;cancer&lt;/highlight&gt; et aux paramètres épidémiologiques.
1004
- Résultats. - La fréquence globale des &lt;highlight&gt;cancers&lt;/highlight&gt;
1005
- urologiques était de 17,38%. Il s''agissait de &lt;highlight&gt;cancer&lt;/highlight&gt;
1006
- prostatique (69%), de vessie (28,5%), du rein (8,5%) et les &lt;highlight&gt;cancers&lt;/highlight&gt;
1007
- des organes génitaux externes. Ils survenaient à un âge avancé avec une moyenne
1008
- d''âge de 62,89 ± 15,51 ans et étaient l''apanage des sujets de sexe masculin
1009
- avec un sex-ratio de 9/10. Les mortalités spécifiques qui leur sont rattachées
1010
- étaient assez élevées. Les tendances évolutives de ces &lt;highlight&gt;cancers&lt;/highlight&gt;
1011
- dans le service montraient en général une augmentation de leur fréquence au
1012
- fil des années. Conclusion. - Le profil épidémiologique des &lt;highlight&gt;cancers&lt;/highlight&gt;
1013
- urologiques dans notre pratique avait quelques particularités essentielles
1014
- pour la prévention primaire. L''amélioration de la qualité de l''information
1015
- sanitaire en termes d''exhaustivité et de précision, la mise en place d''un
1016
- registre de &lt;highlight&gt;cancer&lt;/highlight&gt; et l''amélioration du
1017
- plateau technique permettront une meilleure prise en charge de ces &lt;highlight&gt;cancers&lt;/highlight&gt;.
1018
- (French)</Data></Item><Item><Name>Subject</Name><Label>Subjects (French)</Label><Group>Su</Group><Data>&lt;searchLink
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- fieldCode="DE" term="%22Urologie%22"&gt;Urologie&lt;/searchLink&gt;; &lt;searchLink
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- &lt;searchLink fieldCode="DE" term="%22Canc%C3%A9rologie%22"&gt;Cancérologie&lt;/searchLink&gt;;
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- &lt;searchLink fieldCode="DE" term="%22Cancer+de+la+vessie%22"&gt;Cancer de
1023
- la vessie&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22B%C3%A9nin%22"&gt;Bénin&lt;/searchLink&gt;;
1024
- &lt;searchLink fieldCode="DE" term="%22Homme%22"&gt;Homme&lt;/searchLink&gt;;
1025
- &lt;searchLink fieldCode="DE" term="%22Cancer+de+la+prostate%22"&gt;Cancer
1026
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- &lt;searchLink fieldCode="DE" term="%22Pathologie+des+voies+urinaires%22"&gt;Pathologie
1034
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1035
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1036
- du rein&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+la+prostate%22"&gt;Pathologie
1037
- de la prostate&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+urinaire%22"&gt;Pathologie
1038
- de lappareil urinaire&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+g%C3%A9nital+m%C3%A2le%22"&gt;Pathologie
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1042
- des organes génitaux externes&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
1043
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1045
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1046
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1048
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1053
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1056
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1057
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1058
- tract disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Bladder+disease%22"&gt;Bladder
1059
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Kidney+disease%22"&gt;Kidney
1060
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Prostate+disease%22"&gt;Prostate
1061
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Urinary+system+disease%22"&gt;Urinary
1062
- system disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Male+genital+diseases%22"&gt;Male
1063
- genital diseases&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Africa%22"&gt;Africa&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
1064
- (Spanish)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Urolog%C3%ADa%22"&gt;Urología&lt;/searchLink&gt;;
1065
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1066
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1067
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+de+la+vejiga%22"&gt;Cáncer
1068
- de la vejiga&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Ben%C3%ADn%22"&gt;Benín&lt;/searchLink&gt;;
1069
- &lt;searchLink fieldCode="DE" term="%22Hombre%22"&gt;Hombre&lt;/searchLink&gt;;
1070
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+de+la+pr%C3%B3stata%22"&gt;Cáncer
1071
- de la próstata&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Retrospectiva%22"&gt;Retrospectiva&lt;/searchLink&gt;;
1072
- &lt;searchLink fieldCode="DE" term="%22Epidemiolog%C3%ADa%22"&gt;Epidemiología&lt;/searchLink&gt;;
1073
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+ri%C3%B1%C3%B3n%22"&gt;Cáncer
1074
- del riñón&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Salud+p%C3%BAblica%22"&gt;Salud
1075
- pública&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+genital+patolog%C3%ADa%22"&gt;Aparato
1076
- genital patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer%22"&gt;Cáncer&lt;/searchLink&gt;;
1077
- &lt;searchLink fieldCode="DE" term="%22Tumor+maligno%22"&gt;Tumor maligno&lt;/searchLink&gt;;
1078
- &lt;searchLink fieldCode="DE" term="%22V%C3%ADa+urinaria+patolog%C3%ADa%22"&gt;Vía
1079
- urinaria patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Vejiga+patolog%C3%ADa%22"&gt;Vejiga
1080
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Ri%C3%B1%C3%B3n+patolog%C3%ADa%22"&gt;Riñón
1081
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Prostata+patolog%C3%ADa%22"&gt;Prostata
1082
- patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+urinario+patolog%C3%ADa%22"&gt;Aparato
1083
- urinario patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Aparato+genital+macho+patolog%C3%ADa%22"&gt;Aparato
1084
- genital macho patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
1085
- term="%22Africa%22"&gt;Africa&lt;/searchLink&gt;</Data></Item></Items></Record><Record><ResultId>9</ResultId><Header><DbId>pcl</DbId><DbLabel>PASCAL</DbLabel><An>25821428</An><RelevancyScore>2357</RelevancyScore><AccessLevel
1086
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1087
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=00070920&amp;title=British+journal+of+cancer&amp;volume=106&amp;issue=9&amp;date=20120101&amp;atitle=The+role+of+miRNAs+in+human+papilloma+virus+(HPV)-associated+cancers%3a+bridging+between+HPV-related+head+and+neck+cancer+and+cervical+cancer&amp;aulast=LAJER%2c+C.+B.&amp;spage=1526&amp;sid=EBSCO:PASCAL&amp;pid=&lt;authors&gt;LAJER%2c+C.+B.&lt;/authors&gt;&lt;ui&gt;25821428&lt;/ui&gt;&lt;date&gt;20120101&lt;/date&gt;&lt;db&gt;PASCAL&lt;/db&gt;</Url><Name>Find
1088
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
1089
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
1090
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
1091
- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>The
1092
- role of miRNAs in human papilloma virus (HPV)-associated &lt;highlight&gt;cancers&lt;/highlight&gt;:
1093
- bridging between HPV-related head and neck &lt;highlight&gt;cancer&lt;/highlight&gt;
1094
- and cervical &lt;highlight&gt;cancer&lt;/highlight&gt; (English)</Data></Item><Item><Name>Author</Name><Label>Author</Label><Group>Au</Group><Data>&lt;searchLink
1095
- fieldCode="AR" term="%22LAJER%2C+C%2E+B%2E%22"&gt;LAJER, C. B.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
1096
- &lt;searchLink fieldCode="AR" term="%22GARNAES%2C+E%2E%22"&gt;GARNAES, E.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
1097
- &lt;searchLink fieldCode="AR" term="%22FRIIS%2DHANSEN%2C+L%2E%22"&gt;FRIIS-HANSEN,
1098
- L.&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;; &lt;searchLink
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- fieldCode="AR" term="%22NORRILD%2C+B%2E%22"&gt;NORRILD, B.&lt;/searchLink&gt;&lt;relatesTo&gt;b3&lt;/relatesTo&gt;;
1100
- &lt;searchLink fieldCode="AR" term="%22THERKILDSEN%2C+M%2E+H%2E%22"&gt;THERKILDSEN,
1101
- M. H.&lt;/searchLink&gt;&lt;relatesTo&gt;b4&lt;/relatesTo&gt;; &lt;searchLink
1102
- fieldCode="AR" term="%22GLUD%2C+M%2E%22"&gt;GLUD, M.&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;;
1103
- &lt;searchLink fieldCode="AR" term="%22ROSSING%2C+M%2E%22"&gt;ROSSING, M.&lt;/searchLink&gt;&lt;relatesTo&gt;b4&lt;/relatesTo&gt;;
1104
- &lt;searchLink fieldCode="AR" term="%22LAJER%2C+H%2E%22"&gt;LAJER, H.&lt;/searchLink&gt;&lt;relatesTo&gt;b5&lt;/relatesTo&gt;;
1105
- &lt;searchLink fieldCode="AR" term="%22SVANE%2C+D%2E%22"&gt;SVANE, D.&lt;/searchLink&gt;&lt;relatesTo&gt;b5&lt;/relatesTo&gt;;
1106
- &lt;searchLink fieldCode="AR" term="%22SKOTTE%2C+L%2E%22"&gt;SKOTTE, L.&lt;/searchLink&gt;&lt;relatesTo&gt;b6&lt;/relatesTo&gt;;
1107
- &lt;searchLink fieldCode="AR" term="%22SPECHT%2C+L%2E%22"&gt;SPECHT, L.&lt;/searchLink&gt;&lt;relatesTo&gt;b7&lt;/relatesTo&gt;;
1108
- &lt;searchLink fieldCode="AR" term="%22BUCHWALD%2C+C%2E%22"&gt;BUCHWALD, C.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
1109
- &lt;searchLink fieldCode="AR" term="%22NIELSEN%2C+F%2E+C%2E%22"&gt;NIELSEN,
1110
- F. C.&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
1111
- fieldCode="JN" term="%22British+journal+of+cancer%22"&gt;British journal of
1112
- cancer&lt;/searchLink&gt; [Br. j. &lt;highlight&gt;cancer&lt;/highlight&gt;],
1113
- 2012, Vol. 106, Issue 9 p1526-1534, 9p&lt;i&gt; ref &lt;/i&gt; 3/4 p.</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>BACKGROUND:
1114
- Although the role of human papilloma virus (HPV) in cervical squamous cell
1115
- carcinoma (CSCC) is well established, the role in head and neck SCC (HNSCC)
1116
- is less clear. MicroRNAs (miRNAs) have a role in the &lt;highlight&gt;cancer&lt;/highlight&gt;
1117
- development, and HPV status may affect the miRNA expression pattern in HNSCC.
1118
- To explore the influence of HPV in HNSCC, we made a comparative miRNA profile
1119
- of HPV-positive (HPV+) and HPV-negative (HPV―) HNSCC against CSCC. METHODS:
1120
- Fresh frozen and laser microdissected-paraffin-embedded samples obtained from
1121
- patients with HPV+/HPV― HNSCC, CSCC and controls were used for microarray
1122
- analysis. Differentially expressed miRNAs in the HPV+ and HPV― HNSCC samples
1123
- were compared with the differentially expressed miRNAs in the CSCC samples.
1124
- RESULTS: Human papilloma virus positive (+) HNSCC had a distinct miRNA profile
1125
- compared with HPV― HNSCC. Significantly more similarity was seen between HPV+
1126
- HNSCC and CSCC than HPV― and CSCC. A set of HPV core miRNAs were identified.
1127
- Of these especially the miR-15a/miR-16/miR195/miR-497 family, miR-143/miR-145
1128
- and the miR-106-363 cluster appear to be important within the known HPV pathogenesis.
1129
- CONCLUSION: This study adds new knowledge to the known pathogenic pathways
1130
- of HPV and substantiates the oncogenic role of HPV in subsets of HNSCCs. (English)</Data></Item><Item><Name>Subject</Name><Label>Subjects
1131
- (French)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Cancer+de+lamygdale+palatine%22"&gt;Cancer
1132
- de lamygdale palatine&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+du+col+de+lut%C3%A9rus%22"&gt;Cancer
1133
- du col de lutérus&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Canc%C3%A9rologie%22"&gt;Cancérologie&lt;/searchLink&gt;;
1134
- &lt;searchLink fieldCode="DE" term="%22Papillomavirus+humain%22"&gt;Papillomavirus
1135
- humain&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Tumeur+maligne%22"&gt;Tumeur
1136
- maligne&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Micro+ARN%22"&gt;Micro
1137
- ARN&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Interf%C3%A9rence+ARN%22"&gt;Interférence
1138
- ARN&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+de+la+t%C3%AAte+et+du+cou%22"&gt;Cancer
1139
- de la tête et du cou&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
1140
- term="%22Pathologie+du+col+de+lut%C3%A9rus%22"&gt;Pathologie du col de lutérus&lt;/searchLink&gt;;
1141
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1142
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1143
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1144
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1145
- fieldCode="DE" term="%22Papovaviridae%22"&gt;Papovaviridae&lt;/searchLink&gt;;
1146
- &lt;searchLink fieldCode="DE" term="%22Papillomavirus%22"&gt;Papillomavirus&lt;/searchLink&gt;;
1147
- &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
1148
- &lt;searchLink fieldCode="DE" term="%22Silence+expression+g%C3%A9nique%22"&gt;Silence
1149
- expression génique&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
1150
- (English)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Palatine+tonsil+cancer%22"&gt;Palatine
1151
- tonsil cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cervical+cancer%22"&gt;Cervical
1152
- cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancerology%22"&gt;Cancerology&lt;/searchLink&gt;;
1153
- &lt;searchLink fieldCode="DE" term="%22Human+papillomavirus%22"&gt;Human papillomavirus&lt;/searchLink&gt;;
1154
- &lt;searchLink fieldCode="DE" term="%22Malignant+tumor%22"&gt;Malignant tumor&lt;/searchLink&gt;;
1155
- &lt;searchLink fieldCode="DE" term="%22Micro+RNA%22"&gt;Micro RNA&lt;/searchLink&gt;;
1156
- &lt;searchLink fieldCode="DE" term="%22RNA+interference%22"&gt;RNA interference&lt;/searchLink&gt;;
1157
- &lt;searchLink fieldCode="DE" term="%22Head+and+neck+cancer%22"&gt;Head and
1158
- neck cancer&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Uterine+cervix+diseases%22"&gt;Uterine
1159
- cervix diseases&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Female+genital+diseases%22"&gt;Female
1160
- genital diseases&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22ENT+disease%22"&gt;ENT
1161
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Virus%22"&gt;Virus&lt;/searchLink&gt;;
1162
- &lt;searchLink fieldCode="DE" term="%22Papovaviridae%22"&gt;Papovaviridae&lt;/searchLink&gt;;
1163
- &lt;searchLink fieldCode="DE" term="%22Papillomavirus%22"&gt;Papillomavirus&lt;/searchLink&gt;;
1164
- &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
1165
- &lt;searchLink fieldCode="DE" term="%22Gene+silencing%22"&gt;Gene silencing&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
1166
- (Spanish)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+de+am%C3%ADgdala+palatina%22"&gt;Cáncer
1167
- de amígdala palatina&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+de+cuello+del+%C3%BAtero%22"&gt;Cáncer
1168
- de cuello del útero&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancerolog%C3%ADa%22"&gt;Cancerología&lt;/searchLink&gt;;
1169
- &lt;searchLink fieldCode="DE" term="%22Human+papillomavirus%22"&gt;Human papillomavirus&lt;/searchLink&gt;;
1170
- &lt;searchLink fieldCode="DE" term="%22Tumor+maligno%22"&gt;Tumor maligno&lt;/searchLink&gt;;
1171
- &lt;searchLink fieldCode="DE" term="%22Micro+ARN%22"&gt;Micro ARN&lt;/searchLink&gt;;
1172
- &lt;searchLink fieldCode="DE" term="%22ARN+interferencia%22"&gt;ARN interferencia&lt;/searchLink&gt;;
1173
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+de+cabeza+y+cuello%22"&gt;Cáncer
1174
- de cabeza y cuello&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
1175
- term="%22Cuello+%C3%BAtero+patolog%C3%ADa%22"&gt;Cuello útero patología&lt;/searchLink&gt;;
1176
- &lt;searchLink fieldCode="DE" term="%22Aparato+genital+hembra+patolog%C3%ADa%22"&gt;Aparato
1177
- genital hembra patología&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE"
1178
- term="%22ORL+patolog%C3%ADa%22"&gt;ORL patología&lt;/searchLink&gt;; &lt;searchLink
1179
- fieldCode="DE" term="%22Virus%22"&gt;Virus&lt;/searchLink&gt;; &lt;searchLink
1180
- fieldCode="DE" term="%22Papovaviridae%22"&gt;Papovaviridae&lt;/searchLink&gt;;
1181
- &lt;searchLink fieldCode="DE" term="%22Papillomavirus%22"&gt;Papillomavirus&lt;/searchLink&gt;;
1182
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer%22"&gt;Cáncer&lt;/searchLink&gt;;
1183
- &lt;searchLink fieldCode="DE" term="%22Silencio+expresi%C3%B3n+gen%C3%A9tica%22"&gt;Silencio
1184
- expresión genética&lt;/searchLink&gt;</Data></Item></Items></Record><Record><ResultId>10</ResultId><Header><DbId>pcl</DbId><DbLabel>PASCAL</DbLabel><An>25855216</An><RelevancyScore>2357</RelevancyScore><AccessLevel
1185
- i:nil="true"/><PubType>Conference</PubType></Header><PLink>http://search.ebscohost.com/login.aspx?direct=true&amp;db=pcl&amp;AN=25855216</PLink><ImageInfo
1186
- i:nil="true"/><CustomLinks><CustomLink><Url>http://findit.library.jhu.edu/resolve?genre=article&amp;isbn=&amp;issn=1165113X&amp;title=La+Lettre+du+canc%c3%a9rologue+(Boulogne)&amp;volume=21&amp;issue=4&amp;date=20120101&amp;atitle=Les+essais+th%c3%a9rapeutiques+PRODIGE+en+cours&amp;aulast=MANFREDI%2c+S.&amp;spage=212&amp;sid=EBSCO:PASCAL&amp;pid=&lt;authors&gt;MANFREDI%2c+S.&lt;/authors&gt;&lt;ui&gt;25855216&lt;/ui&gt;&lt;date&gt;20120101&lt;/date&gt;&lt;db&gt;PASCAL&lt;/db&gt;</Url><Name>Find
1187
- IT</Name><Category>other</Category><Text/><Icon>http://findit.library.jhu.edu/images/jhu_findit.gif</Icon><MouseOverText>FIND
1188
- IT at JHU libraries</MouseOverText></CustomLink></CustomLinks><FullText><Links
1189
- i:nil="true"/><Text><Availability>0</Availability><Value i:nil="true"/></Text><CustomLinks
1190
- i:nil="true"/></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Les
1191
- essais thérapeutiques PRODIGE en cours (French)</Data></Item><Item><Name>TitleAlt</Name><Label>Other
1192
- Title</Label><Group>Ti</Group><Data>PRODIGE ongoing trials (English)</Data></Item><Item><Name>Author</Name><Label>Author</Label><Group>Au</Group><Data>&lt;searchLink
1193
- fieldCode="AR" term="%22MANFREDI%2C+S%2E%22"&gt;MANFREDI, S.&lt;/searchLink&gt;&lt;relatesTo&gt;b1&lt;/relatesTo&gt;;
1194
- &lt;searchLink fieldCode="AR" term="%22APARICIO%2C+T%2E%22"&gt;APARICIO, T.&lt;/searchLink&gt;&lt;relatesTo&gt;b2&lt;/relatesTo&gt;;
1195
- &lt;searchLink fieldCode="AR" term="%22ADENIS%2C+A%2E%22"&gt;ADENIS, A.&lt;/searchLink&gt;&lt;relatesTo&gt;b3&lt;/relatesTo&gt;;
1196
- &lt;searchLink fieldCode="AR" term="%22BENNOUNA%2C+J%2E%22"&gt;BENNOUNA, J.&lt;/searchLink&gt;&lt;relatesTo&gt;b4&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
1197
- fieldCode="JN" term="%22La+Lettre+du+canc%C3%A9rologue+%28Boulogne%29%22"&gt;La
1198
- Lettre du cancérologue (Boulogne)&lt;/searchLink&gt; [Lett. cancérol. (Boulogne)],
1199
- 2012, Vol. 21, Issue 4 p212-215, 4p</Data></Item><Item><Name>Subject</Name><Label>Subjects
1200
- (French)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Carcinome+h%C3%A9patocellulaire%22"&gt;Carcinome
1201
- hépatocellulaire&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer+du+c%C3%B4lon%22"&gt;Cancer
1202
- du côlon&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Homme%22"&gt;Homme&lt;/searchLink&gt;;
1203
- &lt;searchLink fieldCode="DE" term="%22Cancer+du+pancr%C3%A9as%22"&gt;Cancer
1204
- du pancréas&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Canc%C3%A9rologie%22"&gt;Cancérologie&lt;/searchLink&gt;;
1205
- &lt;searchLink fieldCode="DE" term="%22Cancer+du+foie%22"&gt;Cancer du foie&lt;/searchLink&gt;;
1206
- &lt;searchLink fieldCode="DE" term="%22Cancer+de+lestomac%22"&gt;Cancer de
1207
- lestomac&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Essai+clinique%22"&gt;Essai
1208
- clinique&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Traitement%22"&gt;Traitement&lt;/searchLink&gt;;
1209
- &lt;searchLink fieldCode="DE" term="%22Cancer+de+loesophage%22"&gt;Cancer
1210
- de loesophage&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE"
1211
- term="%22Pathologie+du+foie%22"&gt;Pathologie du foie&lt;/searchLink&gt;;
1212
- &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lintestin%22"&gt;Pathologie
1213
- de lintestin&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+du+c%C3%B4lon%22"&gt;Pathologie
1214
- du côlon&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+du+pancr%C3%A9as%22"&gt;Pathologie
1215
- du pancréas&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lestomac%22"&gt;Pathologie
1216
- de lestomac&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
1217
- &lt;searchLink fieldCode="DE" term="%22Tumeur+maligne%22"&gt;Tumeur maligne&lt;/searchLink&gt;;
1218
- &lt;searchLink fieldCode="DE" term="%22Pathologie+de+loesophage%22"&gt;Pathologie
1219
- de loesophage&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pathologie+de+lappareil+digestif%22"&gt;Pathologie
1220
- de lappareil digestif&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
1221
- (English)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Hepatocellular+carcinoma%22"&gt;Hepatocellular
1222
- carcinoma&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Colon+cancer%22"&gt;Colon
1223
- cancer&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Human%22"&gt;Human&lt;/searchLink&gt;;
1224
- &lt;searchLink fieldCode="DE" term="%22Pancreas+cancer%22"&gt;Pancreas cancer&lt;/searchLink&gt;;
1225
- &lt;searchLink fieldCode="DE" term="%22Cancerology%22"&gt;Cancerology&lt;/searchLink&gt;;
1226
- &lt;searchLink fieldCode="DE" term="%22Liver+cancer%22"&gt;Liver cancer&lt;/searchLink&gt;;
1227
- &lt;searchLink fieldCode="DE" term="%22Stomach+cancer%22"&gt;Stomach cancer&lt;/searchLink&gt;;
1228
- &lt;searchLink fieldCode="DE" term="%22Clinical+trial%22"&gt;Clinical trial&lt;/searchLink&gt;;
1229
- &lt;searchLink fieldCode="DE" term="%22Treatment%22"&gt;Treatment&lt;/searchLink&gt;;
1230
- &lt;searchLink fieldCode="DE" term="%22Esophagus+cancer%22"&gt;Esophagus cancer&lt;/searchLink&gt;&lt;br
1231
- /&gt;&lt;searchLink fieldCode="DE" term="%22Hepatic+disease%22"&gt;Hepatic
1232
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Intestinal+disease%22"&gt;Intestinal
1233
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Colonic+disease%22"&gt;Colonic
1234
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Pancreatic+disease%22"&gt;Pancreatic
1235
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Gastric+disease%22"&gt;Gastric
1236
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancer%22"&gt;Cancer&lt;/searchLink&gt;;
1237
- &lt;searchLink fieldCode="DE" term="%22Malignant+tumor%22"&gt;Malignant tumor&lt;/searchLink&gt;;
1238
- &lt;searchLink fieldCode="DE" term="%22Esophageal+disease%22"&gt;Esophageal
1239
- disease&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Digestive+diseases%22"&gt;Digestive
1240
- diseases&lt;/searchLink&gt;</Data></Item><Item><Name>Subject</Name><Label>Subjects
1241
- (Spanish)</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="DE" term="%22Carcinoma+hepatocelular%22"&gt;Carcinoma
1242
- hepatocelular&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+colon%22"&gt;Cáncer
1243
- del colon&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Hombre%22"&gt;Hombre&lt;/searchLink&gt;;
1244
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+p%C3%A1ncreas%22"&gt;Cáncer
1245
- del páncreas&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Cancerolog%C3%ADa%22"&gt;Cancerología&lt;/searchLink&gt;;
1246
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+h%C3%ADgado%22"&gt;Cáncer
1247
- del hígado&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+est%C3%B3mago%22"&gt;Cáncer
1248
- del estómago&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Ensayo+cl%C3%ADnico%22"&gt;Ensayo
1249
- clínico&lt;/searchLink&gt;; &lt;searchLink fieldCode="DE" term="%22Tratamiento%22"&gt;Tratamiento&lt;/searchLink&gt;;
1250
- &lt;searchLink fieldCode="DE" term="%22C%C3%A1ncer+del+es%C3%B3fago%22"&gt;Cáncer
1251
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+ and its treatment, the authors investigate the influence of workplace accommodations
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+ Accommodations that allow women to work fewer hours or that ease the burden
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+ of work could also generate health benefits by reducing workplace demands
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+ and allowing women more time to tend to treatment needs and recovery. In prior
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+ research, the authors found modest labor supply impacts on employment for
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+ Title</Label><Group>TiAlt</Group><Data>Contribución de la flexibilidad psicológica
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+ fieldCode="JN" term="%22Psicothema%22"&gt;Psicothema&lt;/searchLink&gt;. aug2016,
200
+ Vol. 28 Issue 3, p266-271. 6p.</Data></Item><Item><Name>Subject</Name><Label>Subject
201
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Breast+cancer+--+Patients%22"&gt;Breast
202
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Patients&lt;/searchLink&gt;&lt;br
203
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Breast+cancer+--+Treatment%22"&gt;Breast
204
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Treatment&lt;/searchLink&gt;&lt;br
205
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Adaptability+%28Psychology%29%22"&gt;Adaptability
206
+ (Psychology)&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
207
+ term="%22Anxiety%22"&gt;Anxiety&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink
208
+ fieldCode="DE" term="%22Mental+depression%22"&gt;Mental depression&lt;/searchLink&gt;&lt;br
209
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Distress+%28Psychology%29%22"&gt;Distress
210
+ (Psychology)&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract
211
+ (English)</Label><Group>Ab</Group><Data>Background: This study explored the
212
+ contribution of Psychological Flexibility (PF) to predict adjustment to breast
213
+ &lt;highlight&gt;cancer&lt;/highlight&gt;. Method: Sixtyfour females with
214
+ breast &lt;highlight&gt;cancer&lt;/highlight&gt; completed self-report measures
215
+ of PF and adjustment (anxiety, depression, negative and positive affect) at
216
+ baseline, and forty-two patients returned for assessment six months later.
217
+ Results: Higher flexibility at baseline significantly contributed to predict
218
+ lower anxiety, depression and negative affect at follow-up. The effect sizes
219
+ ranged from moderate to large. Conclusions: Results provide evidence for targeting
220
+ PF to prevent enhanced psychological distress in patients with breast &lt;highlight&gt;cancer&lt;/highlight&gt;,
221
+ and add to a growing body of research supporting PF as a common protective
222
+ factor across different contexts and populations. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>Abstract</Name><Label>Abstract
223
+ (Spanish)</Label><Group>Ab</Group><Data>Antecedentes: este estudio explora
224
+ el grado de contribución de la Flexibilidad Psicológica (FP) en el pronóstico
225
+ de diversos indicadores de adaptación al cáncer de mama. Método: 64 mujeres
226
+ con cáncer de mama completaron medidas de FP, ansiedad, depresión, afecto
227
+ negativo y positivo en un primer momento (TI), y 42 de ellas repitieron la
228
+ evaluación seis meses después (T2). Resultados: los resultados indican que
229
+ la FP en TI contribuye significativamente en la predicción de ansiedad, depresión
230
+ y afecto negativo en T2, con tamaños del efecto que oscilan entre moderado
231
+ y grande. Elevados niveles de FP se asocian significativamente con niveles
232
+ más bajos de distrés psicológico. Conclusiones: los resultados apoyan que
233
+ la FP es un factor protector de niveles excesivos de distrés en pacientes
234
+ con cáncer de mama. Estos resultados se suman al creciente cuerpo de evidencias
235
+ que sugiere que la FP es un factor general de protección de la salud mental,
236
+ transversal a diferentes contextos y poblaciones. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
237
+ of Psicothema is the property of Colegio Oficial de Psicologos del Principado
238
+ de Asturias and its content may not be copied or emailed to multiple sites
239
+ or posted to a listserv without the copyright holder''s express written permission.
240
+ However, users may print, download, or email articles for individual use.
241
+ This abstract may be abridged. No warranty is given about the accuracy of
242
+ the copy. Users should refer to the original published version of the material
243
+ for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.7334/psicothema2015.271</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>6</PageCount><StartPage>266</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Breast
244
+ cancer -- Patients</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Breast
245
+ cancer -- Treatment</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Adaptability
246
+ (Psychology)</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Anxiety</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Mental
247
+ depression</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Distress
248
+ (Psychology)</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>On
249
+ the contribution of psychological flexibility to predict adjustment to breast
250
+ cancer.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>Montiel,
251
+ Carmen Berrocal</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Moya,
252
+ Teresa Rivas</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Venditti,
253
+ Francesca</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Bernini,
254
+ Olivia</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>08</M><Text>aug2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>02149915</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>28</Value></Number><Number><Type>issue</Type><Value>3</Value></Number></Numbering><Titles><Title><TitleFull>Psicothema</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>3</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>117242119</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
255
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=117242119</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Spheres
256
+ from cervical &lt;highlight&gt;cancer&lt;/highlight&gt; cells display stemness
257
+ and &lt;highlight&gt;cancer&lt;/highlight&gt; drug resistance.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
258
+ fieldCode="AR" term="%22HUAN+LIU%22"&gt;HUAN LIU&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
259
+ /&gt;&lt;searchLink fieldCode="AR" term="%22HAIJUAN+WANG%22"&gt;HAIJUAN WANG&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
260
+ /&gt;&lt;searchLink fieldCode="AR" term="%22CHUNXIAO+LI%22"&gt;CHUNXIAO LI&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
261
+ /&gt;&lt;searchLink fieldCode="AR" term="%22TINGTING+ZHANG%22"&gt;TINGTING
262
+ ZHANG&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
263
+ fieldCode="AR" term="%22XITING+MENG%22"&gt;XITING MENG&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
264
+ /&gt;&lt;searchLink fieldCode="AR" term="%22YING+ZHANG%22"&gt;YING ZHANG&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;i&gt;
265
+ zyandzm@163.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22HAILI+QIAN%22"&gt;HAILI
266
+ QIAN&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; qianhaili001@163.com&lt;/i&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
267
+ fieldCode="JN" term="%22Oncology+Letters%22"&gt;Oncology Letters&lt;/searchLink&gt;.
268
+ Sep2016, Vol. 12 Issue 3, p2184-2188. 5p.</Data></Item><Item><Name>Subject</Name><Label>Subject
269
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Cervical+cancer+--+Treatment%22"&gt;Cervical
270
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Treatment&lt;/searchLink&gt;&lt;br
271
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Cancer+cells%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
272
+ cells&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE" term="%22Cervical+cancer+--+Patients%22"&gt;Cervical
273
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Patients&lt;/searchLink&gt;&lt;br
274
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Drug+resistance+in+cancer+cells%22"&gt;Drug
275
+ resistance in &lt;highlight&gt;cancer&lt;/highlight&gt; cells&lt;/searchLink&gt;&lt;br
276
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Polymerase+chain+reaction%22"&gt;Polymerase
277
+ chain reaction&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Cervical
278
+ &lt;highlight&gt;cancer&lt;/highlight&gt; is one of the most common gynecological
279
+ malignant tumors and is the cause of a serious health problem worldwide. An
280
+ increasing amount of evidence has shown that &lt;highlight&gt;cancer&lt;/highlight&gt;
281
+ stem cells (CSCs) are present in tumors, and that these CSCs may be responsible
282
+ for tumor metastasis and relapse. The present study aimed to identify and
283
+ characterize a CSC population from the CaSki cell line. First, a stem cell
284
+ culture medium was used to selectively expand the &lt;highlight&gt;cancer&lt;/highlight&gt;
285
+ stem-like cell spheres, and the putative stemness markers, Oct4 and Sox2,
286
+ were identified. These markers were all highly expressed in the CaSki sphere-forming
287
+ cells. Next, target region amplified polymorphism-polymerase chain reaction
288
+ was performed and the CaSki sphere-forming cells were found to exhibit higher
289
+ telomerase activity than the CaSki control cells cultured in non-stem cell
290
+ medium. Using the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-
291
+ (4-sulfophenyl)-2H-tetrazolium assay, it was found that the CaSki sphere-forming
292
+ cells were more resistant to chemotherapeutic drugs than the control CaSki
293
+ cells. Using the tumor invasive assay, it was shown that the CaSki sphere-forming
294
+ cells were more invasive than the control CaSki cells. These characteristics
295
+ all suggested that the tumor sphere-forming cells mirrored the acknowledged
296
+ CSC phenotypes. Overall, the use of a suspended sphere culture of CaSki cells
297
+ may be an easy and feasible approach for enriching &lt;highlight&gt;cancer&lt;/highlight&gt;
298
+ stem-like cells in cervical &lt;highlight&gt;cancer&lt;/highlight&gt; research.
299
+ [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
300
+ of Oncology Letters is the property of Spandidos Publications UK Ltd and its
301
+ content may not be copied or emailed to multiple sites or posted to a listserv
302
+ without the copyright holder''s express written permission. However, users
303
+ may print, download, or email articles for individual use. This abstract may
304
+ be abridged. No warranty is given about the accuracy of the copy. Users should
305
+ refer to the original published version of the material for the full abstract.&lt;/i&gt;
306
+ (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.3892/ol.2016.4893</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>5</PageCount><StartPage>2184</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Cervical
307
+ cancer -- Treatment</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
308
+ cells</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cervical
309
+ cancer -- Patients</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Drug
310
+ resistance in cancer cells</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Polymerase
311
+ chain reaction</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>Spheres
312
+ from cervical cancer cells display stemness and cancer drug resistance.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>HUAN
313
+ LIU</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>HAIJUAN
314
+ WANG</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>CHUNXIAO
315
+ LI</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>TINGTING
316
+ ZHANG</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>XITING
317
+ MENG</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>YING
318
+ ZHANG</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>HAILI
319
+ QIAN</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>09</M><Text>Sep2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>17921074</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>12</Value></Number><Number><Type>issue</Type><Value>3</Value></Number></Numbering><Titles><Title><TitleFull>Oncology
320
+ Letters</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>4</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>118338916</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
321
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=118338916</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Targeted
322
+ &lt;highlight&gt;Cancer&lt;/highlight&gt; Therapy: Vital Oncogenes and a New
323
+ Molecular Genetic Paradigm for &lt;highlight&gt;Cancer&lt;/highlight&gt; Initiation
324
+ Progression and Treatment.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
325
+ fieldCode="AR" term="%22Willis%2C+Rudolph+E%2E%22"&gt;Willis, Rudolph E.&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt;
326
+ rwillis@oncostembio.com&lt;/i&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
327
+ fieldCode="JN" term="%22International+Journal+of+Molecular+Sciences%22"&gt;International
328
+ Journal of Molecular Sciences&lt;/searchLink&gt;. Sep2016, Vol. 17 Issue 9,
329
+ p1-23. 23p.</Data></Item><Item><Name>Subject</Name><Label>Subject Terms</Label><Group>Su</Group><Data>*&lt;searchLink
330
+ fieldCode="DE" term="%22Cancer+treatment%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
331
+ treatment&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE" term="%22Cancer+invasiveness%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
332
+ invasiveness&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
333
+ term="%22Cancer+--+Molecular+aspects%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
334
+ -- Molecular aspects&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
335
+ term="%22Cancer+genetics%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
336
+ genetics&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE" term="%22Carcinogenesis%22"&gt;Carcinogenesis&lt;/searchLink&gt;&lt;br
337
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Cancer+cells%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
338
+ cells&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>It
339
+ has been declared repeatedly that &lt;highlight&gt;cancer&lt;/highlight&gt;
340
+ is a result of molecular genetic abnormalities. However, there has been no
341
+ working model describing the specific functional consequences of the deranged
342
+ genomic processes that result in the initiation and propagation of the &lt;highlight&gt;cancer&lt;/highlight&gt;
343
+ process during carcinogenesis. We no longer need to question whether or not
344
+ &lt;highlight&gt;cancer&lt;/highlight&gt; arises as a result of a molecular
345
+ genetic defect within the &lt;highlight&gt;cancer&lt;/highlight&gt; cell.
346
+ The legitimate questions are: how and why? This article reviews the preeminent
347
+ data on &lt;highlight&gt;cancer&lt;/highlight&gt; molecular genetics and subsequently
348
+ proposes that the sentinel event in &lt;highlight&gt;cancer&lt;/highlight&gt;
349
+ initiation is the aberrant production of fused transcription activators with
350
+ new molecular properties within normal tissue stem cells. This results in
351
+ the production of vital oncogenes with dysfunctional gene activation transcription
352
+ properties, which leads to dysfunctional gene regulation, the aberrant activation
353
+ of transduction pathways, chromosomal breakage, activation of driver oncogenes,
354
+ reactivation of stem cell transduction pathways and the activation of genes
355
+ that result in the hallmarks of &lt;highlight&gt;cancer&lt;/highlight&gt;.
356
+ Furthermore, a novel holistic molecular genetic model of &lt;highlight&gt;cancer&lt;/highlight&gt;
357
+ initiation and progression is presented along with a new paradigm for the
358
+ approach to personalized targeted &lt;highlight&gt;cancer&lt;/highlight&gt;
359
+ therapy, clinical monitoring and &lt;highlight&gt;cancer&lt;/highlight&gt;
360
+ diagnosis. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
361
+ of International Journal of Molecular Sciences is the property of MDPI Publishing
362
+ and its content may not be copied or emailed to multiple sites or posted to
363
+ a listserv without the copyright holder''s express written permission. However,
364
+ users may print, download, or email articles for individual use. This abstract
365
+ may be abridged. No warranty is given about the accuracy of the copy. Users
366
+ should refer to the original published version of the material for the full
367
+ abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.3390/ijms17091552</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>23</PageCount><StartPage>1</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Cancer
368
+ treatment</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
369
+ invasiveness</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
370
+ -- Molecular aspects</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
371
+ genetics</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Carcinogenesis</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
372
+ cells</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>Targeted
373
+ Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer
374
+ Initiation Progression and Treatment.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>Willis,
375
+ Rudolph E.</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>09</M><Text>Sep2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>14220067</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>17</Value></Number><Number><Type>issue</Type><Value>9</Value></Number></Numbering><Titles><Title><TitleFull>International
376
+ Journal of Molecular Sciences</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>5</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>117669540</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
377
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=117669540</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Relationship
378
+ of Predicted Risk of Developing Invasive Breast &lt;highlight&gt;Cancer&lt;/highlight&gt;,
379
+ as Assessed with Three Models, and Breast &lt;highlight&gt;Cancer&lt;/highlight&gt;
380
+ Mortality among Breast &lt;highlight&gt;Cancer&lt;/highlight&gt; Patients.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
381
+ fieldCode="AR" term="%22Sherman%2C+Mark+E%2E%22"&gt;Sherman, Mark E.&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt;
382
+ ShermanM@mail.nih.gov&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22Ichikawa%2C+Laura%22"&gt;Ichikawa,
383
+ Laura&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
384
+ fieldCode="AR" term="%22Pfeiffer%2C+Ruth+M%2E%22"&gt;Pfeiffer, Ruth M.&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br
385
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Miglioretti%2C+Diana+L%2E%22"&gt;Miglioretti,
386
+ Diana L.&lt;/searchLink&gt;&lt;relatesTo&gt;2,4&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
387
+ fieldCode="AR" term="%22Kerlikowske%2C+Karla%22"&gt;Kerlikowske, Karla&lt;/searchLink&gt;&lt;relatesTo&gt;5&lt;/relatesTo&gt;&lt;br
388
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Tice%2C+Jeffery%22"&gt;Tice, Jeffery&lt;/searchLink&gt;&lt;relatesTo&gt;6&lt;/relatesTo&gt;&lt;br
389
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Vacek%2C+Pamela+M%2E%22"&gt;Vacek,
390
+ Pamela M.&lt;/searchLink&gt;&lt;relatesTo&gt;7&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
391
+ fieldCode="AR" term="%22Gierach%2C+Gretchen+L%2E%22"&gt;Gierach, Gretchen
392
+ L.&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
393
+ fieldCode="JN" term="%22PLoS+ONE%22"&gt;PLoS ONE&lt;/searchLink&gt;. 8/25/2016,
394
+ Vol. 11 Issue 8, p1-15. 15p.</Data></Item><Item><Name>Subject</Name><Label>Subject
395
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Breast+cancer+--+Risk+factors%22"&gt;Breast
396
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Risk factors&lt;/searchLink&gt;&lt;br
397
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Cancer+invasiveness%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
398
+ invasiveness&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
399
+ term="%22Cancer+--+Mortality%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
400
+ -- Mortality&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
401
+ term="%22Disease+incidence%22"&gt;Disease incidence&lt;/searchLink&gt;&lt;br
402
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Health+counseling%22"&gt;Health
403
+ counseling&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Purpose: Breast
404
+ &lt;highlight&gt;cancer&lt;/highlight&gt; risk prediction models are used
405
+ to plan clinical trials and counsel women; however, relationships of predicted
406
+ risks of breast &lt;highlight&gt;cancer&lt;/highlight&gt; incidence and prognosis
407
+ after breast &lt;highlight&gt;cancer&lt;/highlight&gt; diagnosis are unknown.
408
+ Methods: Using largely pre-diagnostic information from the Breast &lt;highlight&gt;Cancer&lt;/highlight&gt;
409
+ Surveillance Consortium (BCSC) for 37,939 invasive breast &lt;highlight&gt;cancers&lt;/highlight&gt;
410
+ (1996–2007), we estimated 5-year breast &lt;highlight&gt;cancer&lt;/highlight&gt;
411
+ risk (&lt;1%; 1–1.66%; ≥1.67%) with three models: BCSC 1-year risk model (BCSC-1;
412
+ adapted to 5-year predictions); Breast &lt;highlight&gt;Cancer&lt;/highlight&gt;
413
+ Risk Assessment Tool (BCRAT); and BCSC 5-year risk model (BCSC-5). Breast
414
+ &lt;highlight&gt;cancer&lt;/highlight&gt;-specific mortality post-diagnosis
415
+ (range: 1–13 years; median: 5.4–5.6 years) was related to predicted risk of
416
+ developing breast &lt;highlight&gt;cancer&lt;/highlight&gt; using unadjusted
417
+ Cox proportional hazards models, and in age-stratified (35–44; 45–54; 55–69;
418
+ 70–89 years) models adjusted for continuous age, BCSC registry, calendar period,
419
+ income, mode of presentation, stage and treatment. Mean age at diagnosis was
420
+ 60 years. Results: Of 6,021 deaths, 2,993 (49.7%) were ascribed to breast
421
+ &lt;highlight&gt;cancer&lt;/highlight&gt;. In unadjusted case-only analyses,
422
+ predicted breast &lt;highlight&gt;cancer&lt;/highlight&gt; risk ≥1.67% versus
423
+ &lt;1.0% was associated with lower risk of breast &lt;highlight&gt;cancer&lt;/highlight&gt;
424
+ death; BCSC-1: hazard ratio (HR) = 0.82 (95% CI = 0.75–0.90); BCRAT: HR =
425
+ 0.72 (95% CI = 0.65–0.81) and BCSC-5: HR = 0.84 (95% CI = 0.75–0.94). Age-stratified,
426
+ adjusted models showed similar, although mostly non-significant HRs. Among
427
+ women ages 55–69 years, HRs approximated 1.0. Generally, higher predicted
428
+ risk was inversely related to percentages of &lt;highlight&gt;cancers&lt;/highlight&gt;
429
+ with unfavorable prognostic characteristics, especially among women 35–44
430
+ years. Conclusions: Among cases assessed with three models, higher predicted
431
+ risk of developing breast &lt;highlight&gt;cancer&lt;/highlight&gt; was not
432
+ associated with greater risk of breast &lt;highlight&gt;cancer&lt;/highlight&gt;
433
+ death; thus, these models would have limited utility in planning studies to
434
+ evaluate breast &lt;highlight&gt;cancer&lt;/highlight&gt; mortality reduction
435
+ strategies. Further, when offering women counseling, it may be useful to note
436
+ that high predicted risk of developing breast &lt;highlight&gt;cancer&lt;/highlight&gt;
437
+ does not imply that if &lt;highlight&gt;cancer&lt;/highlight&gt; develops
438
+ it will behave aggressively. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
439
+ of PLoS ONE is the property of Public Library of Science and its content may
440
+ not be copied or emailed to multiple sites or posted to a listserv without
441
+ the copyright holder''s express written permission. However, users may print,
442
+ download, or email articles for individual use. This abstract may be abridged.
443
+ No warranty is given about the accuracy of the copy. Users should refer to
444
+ the original published version of the material for the full abstract.&lt;/i&gt;
445
+ (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.1371/journal.pone.0160966</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>15</PageCount><StartPage>1</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Breast
446
+ cancer -- Risk factors</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
447
+ invasiveness</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
448
+ -- Mortality</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Disease
449
+ incidence</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Health
450
+ counseling</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>Relationship
451
+ of Predicted Risk of Developing Invasive Breast Cancer, as Assessed with Three
452
+ Models, and Breast Cancer Mortality among Breast Cancer Patients.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>Sherman,
453
+ Mark E.</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Ichikawa,
454
+ Laura</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Pfeiffer,
455
+ Ruth M.</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Miglioretti,
456
+ Diana L.</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Kerlikowske,
457
+ Karla</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Tice,
458
+ Jeffery</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Vacek,
459
+ Pamela M.</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Gierach,
460
+ Gretchen L.</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>25</D><M>08</M><Text>8/25/2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>19326203</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>11</Value></Number><Number><Type>issue</Type><Value>8</Value></Number></Numbering><Titles><Title><TitleFull>PLoS
461
+ ONE</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>6</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>117687084</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
462
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=117687084</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Prognostic
463
+ impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression
464
+ in &lt;highlight&gt;cancer&lt;/highlight&gt; cells and tumor infiltrating
465
+ lymphocytes in colorectal &lt;highlight&gt;cancer&lt;/highlight&gt;.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
466
+ fieldCode="AR" term="%22Yaqi+Li%22"&gt;Yaqi Li&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;br
467
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Lei+Liang%22"&gt;Lei Liang&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;br
468
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Weixing+Dai%22"&gt;Weixing Dai&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;br
469
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Guoxiang+Cai%22"&gt;Guoxiang Cai&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;br
470
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Ye+Xu%22"&gt;Ye Xu&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;br
471
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Xinxiang+Li%22"&gt;Xinxiang Li&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;br
472
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Qingguo+Li%22"&gt;Qingguo Li&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;i&gt;
473
+ oncosurgeonli@sohu.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR"
474
+ term="%22Sanjun+Cai%22"&gt;Sanjun Cai&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt;&lt;i&gt;
475
+ caisanjunsh@163.com&lt;/i&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
476
+ fieldCode="JN" term="%22Molecular+Cancer%22"&gt;Molecular &lt;highlight&gt;Cancer&lt;/highlight&gt;&lt;/searchLink&gt;.
477
+ 8/24/2016, Vol. 15, p1-15. 15p. 1 Diagram, 3 Charts, 3 Graphs.</Data></Item><Item><Name>Subject</Name><Label>Subject
478
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Programmed+cell+death+1+receptors%22"&gt;Programmed
479
+ cell death 1 receptors&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
480
+ term="%22Cancer+cells%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt; cells&lt;/searchLink&gt;&lt;br
481
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Lymphocytes%22"&gt;Lymphocytes&lt;/searchLink&gt;&lt;br
482
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Colon+cancer%22"&gt;Colon &lt;highlight&gt;cancer&lt;/highlight&gt;&lt;/searchLink&gt;</Data></Item><Item><Name>SubjectProduct</Name><Label>Reviews
483
+ &amp; Products</Label><Group>Su</Group><Data>&lt;searchLink fieldCode="PS"
484
+ term="%22Cancer+Genome+Atlas%2C+The+%28Book%29%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
485
+ Genome Atlas, The (Book)&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Background:
486
+ Colorectal &lt;highlight&gt;cancer&lt;/highlight&gt; (CRC) is 3rd most commonly
487
+ diagnosed &lt;highlight&gt;cancer&lt;/highlight&gt; in males and the second
488
+ in females. PD-1/PD-L1 axis, as an immune checkpoint, is up-regulated in many
489
+ tumors and their microenvironment. However, the prognostic value of PD-1/PD-L1
490
+ in CRC remains unclear. Methods: The &lt;highlight&gt;Cancer&lt;/highlight&gt;
491
+ Genome Atlas (TCGA) database (N = 356) and Fudan University Shanghai &lt;highlight&gt;Cancer&lt;/highlight&gt;
492
+ Center (FUSCC) cohort of patients (N = 276) were adopted to analyze the prognostic
493
+ value of PD-L1 in colorectal tumor cells (TCs) and of PD-1 in tumor infiltrating
494
+ cells (TILs) for CRC. Subgroup analyses were conducted in FUSCC cohort according
495
+ to patients'' status of mismatch repair. Results: In TCGA cohort, the cut-off
496
+ values of PD-1 and PD-L1 expression were determined by X-tile program, which
497
+ were 4.40 and 2.92, respectively. Kaplan-Meier analysis indicated that higher
498
+ PD-1 and PD-L1 expressions correlated with better OS (P = 0.032 and P = 0.002,
499
+ respectively). In FUSCC cohort, expressions of PD-1 on TILs and PD-L1 on TCs
500
+ were analyzed separately by immunohistochemistry (IHC) staining based on a
501
+ TMA sample (N = 276) and revealed that both TILs-PD-1 and TCs-PD-L1 were associated
502
+ with OS (P = 0.006 and P = 0.002, respectively) and DFS (P = 0.025 and P =
503
+ 0.004, respectively) of CRC patients. Multivariate Cox regression analysis
504
+ indicated TILs- PD-1 was an independent prognostic factor both for OS and
505
+ DFS of CRC patients (P &lt; 0.05). Subgroup analyses showed that TILs-PD-1
506
+ was an independent prognostic factor for both OS and DFS in CRC patients in
507
+ MSSproficient subgroup (P &lt; 0.05), while neither of them correlated with
508
+ OS or DFS in MSS-deficient subgroup (P &gt; 0.05). Conclusions: Higher expressions
509
+ of PD-1 and PD-L1 correlates with better prognosis of CRC patients. TILs-PD-1
510
+ is an independent prognostic factor for OS and DFS of CRC patients, especially
511
+ for MMR-proficient subgroup. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
512
+ of Molecular &lt;highlight&gt;Cancer&lt;/highlight&gt; is the property of
513
+ BioMed Central and its content may not be copied or emailed to multiple sites
514
+ or posted to a listserv without the copyright holder''s express written permission.
515
+ However, users may print, download, or email articles for individual use.
516
+ This abstract may be abridged. No warranty is given about the accuracy of
517
+ the copy. Users should refer to the original published version of the material
518
+ for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.1186/s12943-016-0539-x</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>15</PageCount><StartPage>1</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Cancer
519
+ Genome Atlas, The (Book)</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Programmed
520
+ cell death 1 receptors</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
521
+ cells</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Lymphocytes</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Colon
522
+ cancer</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>Prognostic
523
+ impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression
524
+ in cancer cells and tumor infiltrating lymphocytes in colorectal cancer.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>Yaqi
525
+ Li</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Lei
526
+ Liang</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Weixing
527
+ Dai</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Guoxiang
528
+ Cai</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Ye
529
+ Xu</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Xinxiang
530
+ Li</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Qingguo
531
+ Li</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Sanjun
532
+ Cai</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>24</D><M>08</M><Text>8/24/2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>14764598</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>15</Value></Number></Numbering><Titles><Title><TitleFull>Molecular
533
+ Cancer</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>7</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>118321028</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
534
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=118321028</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>MicroRNA-210
535
+ interacts with FBXO31 to regulate &lt;highlight&gt;cancer&lt;/highlight&gt;
536
+ proliferation cell cycle and migration in human breast &lt;highlight&gt;cancer&lt;/highlight&gt;.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
537
+ fieldCode="AR" term="%22Dayue+Liu%22"&gt;Dayue Liu&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
538
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Haoming+Xia%22"&gt;Haoming Xia&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
539
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Fang+Wang%22"&gt;Fang Wang&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br
540
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Cui+Chen%22"&gt;Cui Chen&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br
541
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Jianting+Long%22"&gt;Jianting
542
+ Long&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;i&gt; longjt2@mail.sysu.edu.cn&lt;/i&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
543
+ fieldCode="JN" term="%22OncoTargets+%26+Therapy%22"&gt;OncoTargets &amp; Therapy&lt;/searchLink&gt;.
544
+ Aug2016, Vol. 9, p5245-5255. 11p.</Data></Item><Item><Name>Subject</Name><Label>Subject
545
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Breast+cancer+--+Research%22"&gt;Breast
546
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Research&lt;/searchLink&gt;&lt;br
547
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22MicroRNA%22"&gt;MicroRNA&lt;/searchLink&gt;&lt;br
548
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Cancer+cells+--+Proliferation%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
549
+ cells -- Proliferation&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
550
+ term="%22Cancer+cell+migration%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
551
+ cell migration&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
552
+ term="%22Human+cell+cycle%22"&gt;Human cell cycle&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Background:
553
+ In this study, we investigated the functional correlation between microRNA-210
554
+ (miR-210) and gene of F-box protein 31 (FBXO31) in regulating breast &lt;highlight&gt;cancer&lt;/highlight&gt;.
555
+ Methods: Dual-luciferase assay and quantitative real-time polymerase chain
556
+ reaction were used to investigate the binding of miR-210 with FBXO31 and their
557
+ expression patterns in breast &lt;highlight&gt;cancer&lt;/highlight&gt;. miR-210
558
+ was inhibited in breast &lt;highlight&gt;cancer&lt;/highlight&gt; T47D and
559
+ MCF-7 cells to assess its effect on &lt;highlight&gt;cancer&lt;/highlight&gt;
560
+ proliferation, cell cycle progression, and migration. FBXO31 was also downregulated
561
+ in breast &lt;highlight&gt;cancer&lt;/highlight&gt; cells to examine its effect
562
+ on miR-210-mediated breast &lt;highlight&gt;cancer&lt;/highlight&gt; regulation.
563
+ The interaction between miR-210 and FBXO31 was further investigated by examining
564
+ the effect of overexpressing miR-210 on FBXO31-induced suppression of breast
565
+ &lt;highlight&gt;cancer&lt;/highlight&gt; proliferation. Results: FBXO31 was
566
+ the downstream target gene of miR-210 in breast &lt;highlight&gt;cancer&lt;/highlight&gt;.
567
+ miR-210 and FBXO31 are inversely expressed in breast &lt;highlight&gt;cancer&lt;/highlight&gt;
568
+ cell lines. miR-210 downregulation reduced &lt;highlight&gt;cancer&lt;/highlight&gt;
569
+ progression, induced cell cycle arrest, and inhibited &lt;highlight&gt;cancer&lt;/highlight&gt;
570
+ migration in T47D and MCF-7 cells. Tumor suppression by miR-210 downregulation
571
+ was reversed by downregulating FBXO31. In FBXO31-overexpressed breast &lt;highlight&gt;cancer&lt;/highlight&gt;
572
+ cells, upregulating miR-210 also reversed the tumorsuppressive effect of FBXO31
573
+ on breast &lt;highlight&gt;cancer&lt;/highlight&gt; proliferation. Conclusion:
574
+ Our work demonstrated that the expression pattern and tumor regulatory functions
575
+ of miR-210 and FBXO31 are inversely correlated in breast &lt;highlight&gt;cancer&lt;/highlight&gt;.
576
+ [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
577
+ of OncoTargets &amp; Therapy is the property of Dove Medical Press Ltd and
578
+ its content may not be copied or emailed to multiple sites or posted to a
579
+ listserv without the copyright holder''s express written permission. However,
580
+ users may print, download, or email articles for individual use. This abstract
581
+ may be abridged. No warranty is given about the accuracy of the copy. Users
582
+ should refer to the original published version of the material for the full
583
+ abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.2147/OTT.S110969</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>11</PageCount><StartPage>5245</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Breast
584
+ cancer -- Research</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>MicroRNA</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
585
+ cells -- Proliferation</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
586
+ cell migration</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Human
587
+ cell cycle</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>MicroRNA-210
588
+ interacts with FBXO31 to regulate cancer proliferation cell cycle and migration
589
+ in human breast cancer.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>Dayue
590
+ Liu</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Haoming
591
+ Xia</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Fang
592
+ Wang</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Cui
593
+ Chen</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Jianting
594
+ Long</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>08</M><Text>Aug2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>11786930</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>9</Value></Number></Numbering><Titles><Title><TitleFull>OncoTargets
595
+ &amp; Therapy</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>8</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>118285599</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
596
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=118285599</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>"My
597
+ &lt;highlight&gt;cancer&lt;/highlight&gt; is not my deepest concern": life
598
+ course disruption influencing patient pathways and health care needs among
599
+ persons living with colorectal &lt;highlight&gt;cancer&lt;/highlight&gt;.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
600
+ fieldCode="AR" term="%22Salamonsen%2C+Anita%22"&gt;Salamonsen, Anita&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt;
601
+ anita.salamonsen@uit.no&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR"
602
+ term="%22Kiil%2C+Mona+A%2E%22"&gt;Kiil, Mona A.&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br
603
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Kristoffersen%2C+Agnete+Egilsdatter%22"&gt;Kristoffersen,
604
+ Agnete Egilsdatter&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
605
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Stub%2C+Trine%22"&gt;Stub, Trine&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
606
+ /&gt;&lt;searchLink fieldCode="AR" term="%22Berntsen%2C+Gro+R%2E%22"&gt;Berntsen,
607
+ Gro R.&lt;/searchLink&gt;&lt;relatesTo&gt;1,3&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
608
+ fieldCode="JN" term="%22Patient+Preference+%26+Adherence%22"&gt;Patient Preference
609
+ &amp; Adherence&lt;/searchLink&gt;. Aug2016, Vol. 10, p1591-1600. 10p.</Data></Item><Item><Name>Subject</Name><Label>Subject
610
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Colon+cancer+--+Patients%22"&gt;Colon
611
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Patients&lt;/searchLink&gt;&lt;br
612
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Guidelines%22"&gt;Guidelines&lt;/searchLink&gt;&lt;br
613
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Rectal+cancer+--+Diagnosis%22"&gt;Rectal
614
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Diagnosis&lt;/searchLink&gt;&lt;br
615
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Mental+depression%22"&gt;Mental
616
+ depression&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode="DE" term="%22Medical+care+--+Norway%22"&gt;Medical
617
+ care -- Norway&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>Background:
618
+ The concept of "patient pathways" in &lt;highlight&gt;cancer&lt;/highlight&gt;
619
+ care is most commonly understood as clinical pathways, operationalized as
620
+ standardized packages of health care based on guidelines for the condition
621
+ in question. In this understanding, patient pathways do not address multimorbidity
622
+ or patient experiences and preferences. This study explored patient pathways
623
+ understood as the individual and cultural life course, which includes both
624
+ life and health events. The overall aim was to contribute to supportive and
625
+ targeted &lt;highlight&gt;cancer&lt;/highlight&gt; care. Materials and methods:
626
+ Nine Norwegian patients recently diagnosed with rectal &lt;highlight&gt;cancer&lt;/highlight&gt;
627
+ Tumor-Node-Metastasis stage I-III participated in qualitative interviews,
628
+ five times over 1 year. Five patients later participated in a workshop where
629
+ they made illustrations of and discussed patient pathways. Results: Patient
630
+ pathways including both health and life events were illustrated and described
631
+ as complex and circular. Stress, anxiety, and depression caused by life events
632
+ had significant disruptive effects and influenced patient-defined health care
633
+ needs. The participants experienced the Norwegian public health service as
634
+ focused on hospital-based standardized &lt;highlight&gt;cancer&lt;/highlight&gt;
635
+ care. They expressed unmet health care needs in terms of emotional and practical
636
+ support in their everyday life with &lt;highlight&gt;cancer&lt;/highlight&gt;,
637
+ and some turned to complementary and alternative medicine. Conclusion: This
638
+ study suggests that acknowledging life course disruption before &lt;highlight&gt;cancer&lt;/highlight&gt;
639
+ diagnosis may have significant relevance for understanding complex patient
640
+ pathways and individual health care needs. Approaching patient pathways as
641
+ individual and socially constructed may contribute important knowledge to
642
+ support targeted &lt;highlight&gt;cancer&lt;/highlight&gt; care. [ABSTRACT
643
+ FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
644
+ of Patient Preference &amp; Adherence is the property of Dove Medical Press
645
+ Ltd and its content may not be copied or emailed to multiple sites or posted
646
+ to a listserv without the copyright holder''s express written permission.
647
+ However, users may print, download, or email articles for individual use.
648
+ This abstract may be abridged. No warranty is given about the accuracy of
649
+ the copy. Users should refer to the original published version of the material
650
+ for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.2147/PPA.S108422</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>10</PageCount><StartPage>1591</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Colon
651
+ cancer -- Patients</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Guidelines</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Rectal
652
+ cancer -- Diagnosis</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Mental
653
+ depression</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Medical
654
+ care -- Norway</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>"My
655
+ cancer is not my deepest concern": life course disruption influencing patient
656
+ pathways and health care needs among persons living with colorectal cancer.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>Salamonsen,
657
+ Anita</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Kiil,
658
+ Mona A.</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Kristoffersen,
659
+ Agnete Egilsdatter</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Stub,
660
+ Trine</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>Berntsen,
661
+ Gro R.</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>08</M><Text>Aug2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>1177889X</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>10</Value></Number></Numbering><Titles><Title><TitleFull>Patient
662
+ Preference &amp; Adherence</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>9</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>116924770</An><RelevancyScore>2152</RelevancyScore><PubType>Academic
663
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=116924770</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>&lt;highlight&gt;Cancer&lt;/highlight&gt;
664
+ of unknown primary ultimately diagnosed as male breast &lt;highlight&gt;cancer&lt;/highlight&gt;:
665
+ A rare case report.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
666
+ fieldCode="AR" term="%22RIGAKOS%2C+GEORGIOS%22"&gt;RIGAKOS, GEORGIOS&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
667
+ /&gt;&lt;searchLink fieldCode="AR" term="%22VAKOS%2C+AMANDA%22"&gt;VAKOS,
668
+ AMANDA&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
669
+ fieldCode="AR" term="%22PAPADOPOULOS%2C+SOTIRIOS%22"&gt;PAPADOPOULOS, SOTIRIOS&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt;
670
+ sotpapado@gmail.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22VERNADOU%2C+ANASTASIA%22"&gt;VERNADOU,
671
+ ANASTASIA&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
672
+ fieldCode="AR" term="%22TSIMPIDAKIS%2C+ANTONIOS%22"&gt;TSIMPIDAKIS, ANTONIOS&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
673
+ /&gt;&lt;searchLink fieldCode="AR" term="%22PAPACHRISTOU%2C+DIONYSIOS%22"&gt;PAPACHRISTOU,
674
+ DIONYSIOS&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
675
+ fieldCode="AR" term="%22RAZIS%2C+EVANGELIA%22"&gt;RAZIS, EVANGELIA&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
676
+ fieldCode="JN" term="%22Molecular+%26+Clinical+Oncology%22"&gt;Molecular &amp;
677
+ Clinical Oncology&lt;/searchLink&gt;. Aug2016, Vol. 5 Issue 2, p263-266. 4p.</Data></Item><Item><Name>Subject</Name><Label>Subject
678
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Breast+cancer+in+men%22"&gt;Breast
679
+ &lt;highlight&gt;cancer&lt;/highlight&gt; in men&lt;/searchLink&gt;&lt;br
680
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Immunohistochemistry%22"&gt;Immunohistochemistry&lt;/searchLink&gt;&lt;br
681
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Breast+cancer+--+Treatment%22"&gt;Breast
682
+ &lt;highlight&gt;cancer&lt;/highlight&gt; -- Treatment&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>&lt;highlight&gt;Cancers&lt;/highlight&gt;
683
+ of unknown primary (CUP) constitute a significant diagnostic and therapeutic
684
+ challenge for clinicians and a frequent cause of &lt;highlight&gt;cancer&lt;/highlight&gt;-related
685
+ mortality in Western countries. Immunohistochemistry assays are commonly used
686
+ to identify the primary &lt;highlight&gt;cancer&lt;/highlight&gt;, but fail
687
+ in approximately one-third of cases. The identification of the possible origin
688
+ of CUP is crucial, as it may help select the appropriate treatment options.
689
+ We herein present the case of a 54-year-old male patient, who presented with
690
+ lower back pain in June, 2013. Following a thorough investigation, the clinical
691
+ and pathological findings could not identify the primary &lt;highlight&gt;cancer&lt;/highlight&gt;,
692
+ leading towards a misdiagnosis. Ultimately, microRNA testing of the resected
693
+ spine lesion was able to identify the primary tumor as male breast &lt;highlight&gt;cancer&lt;/highlight&gt;
694
+ and allow for optimal treatment of the patient. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
695
+ of Molecular &amp; Clinical Oncology is the property of Spandidos Publications
696
+ UK Ltd and its content may not be copied or emailed to multiple sites or posted
697
+ to a listserv without the copyright holder''s express written permission.
698
+ However, users may print, download, or email articles for individual use.
699
+ This abstract may be abridged. No warranty is given about the accuracy of
700
+ the copy. Users should refer to the original published version of the material
701
+ for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.3892/mco.2016.912</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>4</PageCount><StartPage>263</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Breast
702
+ cancer in men</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Immunohistochemistry</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Breast
703
+ cancer -- Treatment</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>Cancer
704
+ of unknown primary ultimately diagnosed as male breast cancer: A rare case
705
+ report.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>RIGAKOS,
706
+ GEORGIOS</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>VAKOS,
707
+ AMANDA</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>PAPADOPOULOS,
708
+ SOTIRIOS</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>VERNADOU,
709
+ ANASTASIA</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>TSIMPIDAKIS,
710
+ ANTONIOS</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>PAPACHRISTOU,
711
+ DIONYSIOS</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>RAZIS,
712
+ EVANGELIA</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>08</M><Text>Aug2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>20499450</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>5</Value></Number><Number><Type>issue</Type><Value>2</Value></Number></Numbering><Titles><Title><TitleFull>Molecular
713
+ &amp; Clinical Oncology</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record><Record><ResultId>10</ResultId><Header><DbId>a9h</DbId><DbLabel/><An>117840971</An><RelevancyScore>2148</RelevancyScore><PubType>Academic
714
+ Journal</PubType><PubTypeId>academicJournal</PubTypeId></Header><PLink>http://0-search.ebscohost.com.lawpac.lawnet.fordham.edu/login.aspx?direct=true&amp;site=eds-live&amp;db=a9h&amp;AN=117840971</PLink><FullText><Links><Link><Type>pdflink</Type></Link></Links><Text><Availability>0</Availability></Text></FullText><Items><Item><Name>Title</Name><Label>Title</Label><Group>Ti</Group><Data>Side
715
+ population cells from long-term passage non-small cell lung &lt;highlight&gt;cancer&lt;/highlight&gt;
716
+ cells display loss of &lt;highlight&gt;cancer&lt;/highlight&gt; stem cell-like
717
+ properties and chemoradioresistance.</Data></Item><Item><Name>Author</Name><Label>Authors</Label><Group>Au</Group><Data>&lt;searchLink
718
+ fieldCode="AR" term="%22HAO+GU%22"&gt;HAO GU&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
719
+ /&gt;&lt;searchLink fieldCode="AR" term="%22XIN-YU+WU%22"&gt;XIN-YU WU&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br
720
+ /&gt;&lt;searchLink fieldCode="AR" term="%22RUI-TAI+FAN%22"&gt;RUI-TAI FAN&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt;
721
+ fanruitai@hotmail.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode="AR" term="%22XIN+WANG%22"&gt;XIN
722
+ WANG&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink
723
+ fieldCode="AR" term="%22YOU-ZHONG+GUO%22"&gt;YOU-ZHONG GUO&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br
724
+ /&gt;&lt;searchLink fieldCode="AR" term="%22RUI+WANG%22"&gt;RUI WANG&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;</Data></Item><Item><Name>TitleSource</Name><Label>Source</Label><Group>Src</Group><Data>&lt;searchLink
725
+ fieldCode="JN" term="%22Oncology+Letters%22"&gt;Oncology Letters&lt;/searchLink&gt;.
726
+ Oct2016, Vol. 12 Issue 4, p2886-2893. 8p.</Data></Item><Item><Name>Subject</Name><Label>Subject
727
+ Terms</Label><Group>Su</Group><Data>*&lt;searchLink fieldCode="DE" term="%22Non-small-cell+lung+carcinoma%22"&gt;Non-small-cell
728
+ lung carcinoma&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE"
729
+ term="%22Cancer+stem+cells%22"&gt;&lt;highlight&gt;Cancer&lt;/highlight&gt;
730
+ stem cells&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink fieldCode="DE" term="%22Doxorubicin%22"&gt;Doxorubicin&lt;/searchLink&gt;&lt;br
731
+ /&gt;*&lt;searchLink fieldCode="DE" term="%22Chemotherapy+%28Cancer%29%22"&gt;Chemotherapy
732
+ (&lt;highlight&gt;Cancer&lt;/highlight&gt;)&lt;/searchLink&gt;&lt;br /&gt;*&lt;searchLink
733
+ fieldCode="DE" term="%22Primary+cells%22"&gt;Primary cells&lt;/searchLink&gt;</Data></Item><Item><Name>Abstract</Name><Label>Abstract</Label><Group>Ab</Group><Data>The
734
+ side population (SP) assay is a widely used method for isolating stem cell-like
735
+ cells from &lt;highlight&gt;cancer&lt;/highlight&gt; cell lines and primary
736
+ cells. The &lt;highlight&gt;cancer&lt;/highlight&gt; cells used in different
737
+ laboratories have been passaged for different generations. Emerging evidence
738
+ revealed that repeated passaging of cell lines for multiple generations frequently
739
+ leads to change of characteristics. Thus, it is worth investigating the effects
740
+ of repeated passaging on the biological and functional properties of the enriched
741
+ SP fraction from early- and late-passage cells. The present study reports
742
+ that the &lt;highlight&gt;cancer&lt;/highlight&gt; stem cell (CSC) characteristics,
743
+ including increased frequency of tumor-initiating and self-renewal capacity,
744
+ and resistance to the chemotherapy agent doxorubicin and ionizing radiation,
745
+ was diminished in SP cells from late-passage non-small cell lung &lt;highlight&gt;cancer&lt;/highlight&gt;
746
+ (NSCLC) cells. This finding revealed that the SP from long-term passage NSCLC
747
+ cells was not consistently enriched for stem cell-like &lt;highlight&gt;cancer&lt;/highlight&gt;
748
+ cells, and low-passage cell lines and primary &lt;highlight&gt;cancer&lt;/highlight&gt;
749
+ cells are therefore recommended in the CSCs field. [ABSTRACT FROM AUTHOR]</Data></Item><Item><Name>AbstractSuppliedCopyright</Name><Label/><Group>Ab</Group><Data>&lt;i&gt;Copyright
750
+ of Oncology Letters is the property of Spandidos Publications UK Ltd and its
751
+ content may not be copied or emailed to multiple sites or posted to a listserv
752
+ without the copyright holder''s express written permission. However, users
753
+ may print, download, or email articles for individual use. This abstract may
754
+ be abridged. No warranty is given about the accuracy of the copy. Users should
755
+ refer to the original published version of the material for the full abstract.&lt;/i&gt;
756
+ (Copyright applies to all Abstracts.)</Data></Item></Items><RecordInfo><BibRecord><BibEntity><Identifiers><Identifier><Type>doi</Type><Value>10.3892/ol.2016.4934</Value></Identifier></Identifiers><Languages><Language><Code>eng</Code><Text>English</Text></Language></Languages><PhysicalDescription><Pagination><PageCount>8</PageCount><StartPage>2886</StartPage></Pagination></PhysicalDescription><Subjects><Subject><SubjectFull>Non-small-cell
757
+ lung carcinoma</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Cancer
758
+ stem cells</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Doxorubicin</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Chemotherapy
759
+ (Cancer)</SubjectFull><Type>general</Type></Subject><Subject><SubjectFull>Primary
760
+ cells</SubjectFull><Type>general</Type></Subject></Subjects><Titles><Title><TitleFull>Side
761
+ population cells from long-term passage non-small cell lung cancer cells display
762
+ loss of cancer stem cell-like properties and chemoradioresistance.</TitleFull><Type>main</Type></Title></Titles></BibEntity><BibRelationships><HasContributorRelationships><HasContributor><PersonEntity><Name><NameFull>HAO
763
+ GU</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>XIN-YU
764
+ WU</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>RUI-TAI
765
+ FAN</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>XIN
766
+ WANG</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>YOU-ZHONG
767
+ GUO</NameFull></Name></PersonEntity></HasContributor><HasContributor><PersonEntity><Name><NameFull>RUI
768
+ WANG</NameFull></Name></PersonEntity></HasContributor></HasContributorRelationships><IsPartOfRelationships><IsPartOf><BibEntity><Dates><Date><D>01</D><M>10</M><Text>Oct2016</Text><Type>published</Type><Y>2016</Y></Date></Dates><Identifiers><Identifier><Type>issn-print</Type><Value>17921074</Value></Identifier></Identifiers><Numbering><Number><Type>volume</Type><Value>12</Value></Number><Number><Type>issue</Type><Value>4</Value></Number></Numbering><Titles><Title><TitleFull>Oncology
769
+ Letters</TitleFull><Type>main</Type></Title></Titles></BibEntity></IsPartOf></IsPartOfRelationships></BibRelationships></BibRecord></RecordInfo></Record></Records></Data><AvailableFacets><AvailableFacet><Id>SourceType</Id><Label>Source
770
+ Type</Label><AvailableFacetValues><AvailableFacetValue><Value>Academic Journals</Value><Count>871086</Count><AddAction>addfacetfilter(SourceType:Academic
771
+ Journals)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>Magazines</Value><Count>70894</Count><AddAction>addfacetfilter(SourceType:Magazines)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>News</Value><Count>25040</Count><AddAction>addfacetfilter(SourceType:News)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>Reviews</Value><Count>6169</Count><AddAction>addfacetfilter(SourceType:Reviews)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>Reports</Value><Count>3633</Count><AddAction>addfacetfilter(SourceType:Reports)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>Books</Value><Count>1963</Count><AddAction>addfacetfilter(SourceType:Books)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>Primary
772
+ Source Documents</Value><Count>17</Count><AddAction>addfacetfilter(SourceType:Primary
773
+ Source Documents)</AddAction></AvailableFacetValue></AvailableFacetValues></AvailableFacet><AvailableFacet><Id>SubjectEDS</Id><Label>Subject</Label><AvailableFacetValues><AvailableFacetValue><Value>cancer</Value><Count>80606</Count><AddAction>addfacetfilter(SubjectEDS:cancer)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>research</Value><Count>61845</Count><AddAction>addfacetfilter(SubjectEDS:research)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>breast
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+ cancer</Value><Count>55714</Count><AddAction>addfacetfilter(SubjectEDS:breast
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+ cells)</AddAction></AvailableFacetValue><AvailableFacetValue><Value>cancer
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783
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784
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785
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786
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787
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788
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789
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790
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791
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792
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793
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794
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795
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796
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797
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798
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799
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800
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801
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802
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803
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804
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805
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806
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807
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808
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809
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810
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811
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812
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813
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814
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815
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816
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817
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818
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819
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820
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823
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824
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825
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826
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827
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829
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831
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833
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835
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837
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838
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839
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840
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841
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842
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843
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868
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888
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891
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896
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902
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904
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928
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932
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1330
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1334
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962
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1337
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1338
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1340
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1345
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1347
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1351
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1353
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1355
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1356
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1357
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1359
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1360
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1361
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1362
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1363
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1364
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1365
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1366
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1367
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1369
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1371
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1373
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1374
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1377
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1379
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1380
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1381
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1382
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1383
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1030
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1033
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1497
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1498
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1499
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1500
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1511
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1515
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1536
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1538
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1539
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