xenosite-forest 0.1.0__tar.gz

xenosite_forest-0.1.0/.gitignore

@@ -0,0 +1,33 @@
+# Caches and virtualenvs
+.venv/
+.pytest_cache/
+.hypothesis/
+.ruff_cache/
+.mypy_cache/
+__pycache__/
+*.py[cod]
+*$py.class
+*.egg-info/
+.python-version
+
+# Build artifacts
+build/
+dist/
+src/xenosite/forest/_version.py
+
+# Editors and OS
+.vscode/
+.idea/
+.DS_Store
+*.swp
+*.bak
+
+# Secrets and local env
+.env
+.env.*
+
+# Local data (never ship)
+data/
+_api
+.cenv
+.devcontainer

xenosite_forest-0.1.0/CITATION.cff

@@ -0,0 +1,39 @@
+cff-version: 1.2.0
+message: If you use this software, please cite the Metabolic Forest paper.
+title: xenosite.forest
+authors:
+  - family-names: Hughes
+    given-names: Tyler B.
+  - family-names: Dang
+    given-names: Na Le
+  - family-names: Kumar
+    given-names: Ayush
+  - family-names: Flynn
+    given-names: Noah R.
+  - family-names: Swamidass
+    given-names: S. Joshua
+    email: swamidass@gmail.com
+license: MIT
+repository-code: https://github.com/swamidasslab/xenosite-forest
+url: https://xenosite.org
+preferred-citation:
+  type: article
+  title: "Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites"
+  authors:
+    - family-names: Hughes
+      given-names: Tyler B.
+    - family-names: Dang
+      given-names: Na Le
+    - family-names: Kumar
+      given-names: Ayush
+    - family-names: Flynn
+      given-names: Noah R.
+    - family-names: Swamidass
+      given-names: S. Joshua
+  journal: Journal of Chemical Information and Modeling
+  year: 2020
+  volume: "60"
+  issue: "10"
+  pages: 4702-4716
+  doi: 10.1021/acs.jcim.0c00360
+  url: https://doi.org/10.1021/acs.jcim.0c00360

xenosite_forest-0.1.0/LICENSE

@@ -0,0 +1,21 @@
+MIT License
+
+Copyright (c) 2026 S. Joshua Swamidass
+
+Permission is hereby granted, free of charge, to any person obtaining a copy
+of this software and associated documentation files (the "Software"), to deal
+in the Software without restriction, including without limitation the rights
+to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+copies of the Software, and to permit persons to whom the Software is
+furnished to do so, subject to the following conditions:
+
+The above copyright notice and this permission notice shall be included in all
+copies or substantial portions of the Software.
+
+THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+SOFTWARE.

xenosite_forest-0.1.0/PKG-INFO

@@ -0,0 +1,195 @@
+Metadata-Version: 2.5
+Name: xenosite-forest
+Version: 0.1.0
+Summary: Metabolic Forest: enumerate metabolite structures from reaction rules
+Project-URL: Homepage, https://xenosite.org
+Project-URL: Documentation, https://github.com/swamidasslab/xenosite-forest/blob/main/docs/usage.md
+Project-URL: Repository, https://github.com/swamidasslab/xenosite-forest
+Project-URL: Issues, https://github.com/swamidasslab/xenosite-forest/issues
+Project-URL: Paper, https://doi.org/10.1021/acs.jcim.0c00360
+Author-email: "S. Joshua Swamidass" <swamidass@gmail.com>
+License: MIT License
+        
+        Copyright (c) 2026 S. Joshua Swamidass
+        
+        Permission is hereby granted, free of charge, to any person obtaining a copy
+        of this software and associated documentation files (the "Software"), to deal
+        in the Software without restriction, including without limitation the rights
+        to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
+        copies of the Software, and to permit persons to whom the Software is
+        furnished to do so, subject to the following conditions:
+        
+        The above copyright notice and this permission notice shall be included in all
+        copies or substantial portions of the Software.
+        
+        THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
+        IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
+        FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
+        AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
+        LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
+        OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
+        SOFTWARE.
+License-File: LICENSE
+Keywords: metabolic-forest,metabolism,metabolite,rdkit,xenosite
+Classifier: Intended Audience :: Science/Research
+Classifier: License :: OSI Approved :: MIT License
+Classifier: Operating System :: OS Independent
+Classifier: Programming Language :: Python :: 3
+Classifier: Programming Language :: Python :: 3.10
+Classifier: Programming Language :: Python :: 3.11
+Classifier: Programming Language :: Python :: 3.12
+Classifier: Topic :: Scientific/Engineering :: Chemistry
+Requires-Python: >=3.10
+Requires-Dist: rdkit>=2023.9.1
+Provides-Extra: network
+Requires-Dist: networkx>=3.2.1; extra == 'network'
+Requires-Dist: tqdm>=4.66.0; extra == 'network'
+Description-Content-Type: text/markdown
+
+# xenosite.forest
+
+Python implementation of **Metabolic Forest**: enumerate explicit metabolite structures from reaction rules, and search pathways that connect a reactant to a putative product.
+
+Site-of-metabolism *prediction* models (epoxidation, quinonation, Phase I, reactivity, and others) are on the web at **[xenosite.org](https://xenosite.org)**. This package is the structure-enumeration engine, not those neural-network models.
+
+If you use this software, please cite the Metabolic Forest paper (DOI and BibTeX below).
+
+## Install
+
+```bash
+uv add xenosite-forest
+```
+
+or
+
+```bash
+pip install xenosite-forest
+```
+
+Optional NetworkX helpers for building a metabolite graph:
+
+```bash
+uv add "xenosite-forest[network]"
+```
+
+Requires **Python 3.10+** and RDKit.
+
+## Quick start
+
+```python
+from rdkit import Chem
+from xenosite.forest import bfs, rules, PhaseOneRS
+
+# Pathway from ethanol to acetaldehyde
+smiles, steps, mols = next(bfs(["CCO", "CC=O"], ruleset="PhaseOneRS"))
+print(smiles)
+print(steps)
+
+# Enumerate hydroxylation products of propane
+for site, products in rules.Hydroxylation().metabolites(Chem.MolFromSmiles("CCC")):
+    print(site, [Chem.MolToSmiles(p) for p in products])
+
+# Named Phase I ruleset
+print(sorted({rule.name for rule in PhaseOneRS}))
+```
+
+A longer walkthrough is in [`examples/tutorial.ipynb`](https://github.com/swamidasslab/xenosite-forest/blob/main/examples/tutorial.ipynb). API notes are in [`docs/usage.md`](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/usage.md). Rulesets and their papers are in [`docs/rulesets.md`](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/rulesets.md).
+
+### Command line
+
+```bash
+xenosite-forest CCO CC=O --ruleset PhaseOneRS --depth 1
+```
+
+Useful flags: `--all-paths`, `--depth N`, `--phase1` (Phase I site strings), `--max N`, `--ruleset NAME`.
+
+## Rulesets and papers
+
+Pass these names to `bfs(..., ruleset=...)` or `load_ruleset(...)`. Full rule lists, Rainbow colors/hex codes, aliases, and BibTeX are in **[`docs/rulesets.md`](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/rulesets.md)**.
+
+| Ruleset | What it enumerates | Matched paper |
+| --- | --- | --- |
+| `PhaseOneRS` | Phase I: SO, UO, DH, HD, RD | Dang et al., Metabolic Rainbow, *JCIM* 2020. DOI [10.1021/acs.jcim.9b00836](https://doi.org/10.1021/acs.jcim.9b00836) |
+| `SO` / `UO` / `DH` / `HD` / `RD` | One Rainbow color each (see hex table in docs) | Same Rainbow paper; Forest rule lists differ slightly for HD/RD/DH |
+| `QuinoneFormationRS` (`QF`) | Quinone, quinone-imine, and quinone-methide structures | Hughes & Swamidass, *Chem. Res. Toxicol.* 2017. DOI [10.1021/acs.chemrestox.6b00385](https://doi.org/10.1021/acs.chemrestox.6b00385) |
+| `Bioactivation` (`BA`) | Quinone, epoxidation, nitroaromatic reduction, thiophene S-oxidation | Hughes et al., *Chem. Res. Toxicol.* 2021. DOI [10.1021/acs.chemrestox.0c00417](https://doi.org/10.1021/acs.chemrestox.0c00417) |
+| `Full` | Complete Metabolic Forest generator (Phase I, conjugations, quinone, tautomerization) | Hughes et al., Metabolic Forest, *JCIM* 2020. DOI [10.1021/acs.jcim.0c00360](https://doi.org/10.1021/acs.jcim.0c00360) |
+
+Rainbow colorblind-safe hex (Wong / Okabe–Ito, closest to the paper figures): **SO** Stable Oxygenation red `#D55E00`, **UO** Unstable Oxygenation orange `#E69F00`, **DH** Dehydrogenation green `#009E73`, **HD** Hydrolysis blue `#56B4E9`, **RD** Reduction purple `#CC79A7`.
+
+Related single-rule papers: epoxidation ([10.1021/acscentsci.5b00131](https://doi.org/10.1021/acscentsci.5b00131)), N-dealkylation ([10.1021/acs.chemrestox.7b00191](https://doi.org/10.1021/acs.chemrestox.7b00191)), UGT glucuronidation ([10.1093/bioinformatics/btw350](https://doi.org/10.1093/bioinformatics/btw350)), glutathione reactivity ([10.1021/acs.chemrestox.5b00017](https://doi.org/10.1021/acs.chemrestox.5b00017)).
+
+## Documentation
+
+- **[Rulesets and papers](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/rulesets.md)** — every built-in ruleset, Rainbow colors, and publication BibTeX
+- **[Usage](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/usage.md)** — public API and pathway search
+- **[Tutorial notebook](https://github.com/swamidasslab/xenosite-forest/blob/main/examples/tutorial.ipynb)** — interactive walkthrough
+- **[xenosite.org](https://xenosite.org)** — XenoSite models for sites of metabolism and reactivity
+- **[Source repository](https://github.com/swamidasslab/xenosite-forest)** — code, issues, and releases
+
+Import the package as `xenosite.forest`. `xenosite` is a PEP 420 namespace, so other `xenosite.*` packages can be installed alongside this one.
+
+## Citation
+
+Please cite Metabolic Forest if you use this package:
+
+Hughes, T. B.; Dang, N. L.; Kumar, A.; Flynn, N. R.; Swamidass, S. J.
+Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites.
+*J. Chem. Inf. Model.* **2020**, *60* (10), 4702–4716.
+**DOI:** [10.1021/acs.jcim.0c00360](https://doi.org/10.1021/acs.jcim.0c00360)
+
+BibTeX (copy and paste):
+
+```bibtex
+@article{Hughes2020MetabolicForest,
+  title = {Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites},
+  author = {Hughes, Tyler B. and Dang, Na Le and Kumar, Ayush and Flynn, Noah R. and Swamidass, S. Joshua},
+  journal = {Journal of Chemical Information and Modeling},
+  volume = {60},
+  number = {10},
+  pages = {4702--4716},
+  year = {2020},
+  doi = {10.1021/acs.jcim.0c00360},
+  url = {https://doi.org/10.1021/acs.jcim.0c00360},
+  publisher = {American Chemical Society}
+}
+```
+
+A machine-readable citation is also in [`CITATION.cff`](https://github.com/swamidasslab/xenosite-forest/blob/main/CITATION.cff).
+
+## Development
+
+```bash
+git clone https://github.com/swamidasslab/xenosite-forest.git
+cd xenosite-forest
+uv sync --extra network --group dev
+uv run pytest -n auto
+```
+
+Versioning comes from git tags via [hatch-vcs](https://github.com/ofek/hatch-vcs) (setuptools-scm). Tag a release as `vX.Y.Z` (for example `v0.1.0`). On that commit the version is `X.Y.Z`. On later untagged commits it becomes the next patch with a dev suffix and short commit, for example `0.1.1.dev3+gabc1234`. Read it at runtime as `xenosite.forest.__version__`.
+
+Pushing a `v*` tag runs [`.github/workflows/release.yml`](https://github.com/swamidasslab/xenosite-forest/blob/main/.github/workflows/release.yml): tests must pass and the resolved version must be a clean `X.Y.Z` before a GitHub Release and PyPI upload. A red tag workflow means do not treat that tag as released. To *block* creating tags unless checks pass, add a GitHub Ruleset on `refs/tags/v*` that requires the `release` / `test` status checks.
+
+### One-time PyPI Trusted Publishing setup
+
+No API token is stored in the repo. CI authenticates with [Trusted Publishing](https://docs.pypi.org/trusted-publishers/) (OIDC).
+
+1. Create the GitHub repo `swamidasslab/xenosite-forest` and push `main`.
+2. GitHub → **Settings → Environments** → create an environment named exactly `pypi` (optional: require reviewers before deploy).
+3. On [PyPI](https://pypi.org/manage/account/publishing/): add a **pending** trusted publisher (project does not need to exist yet):
+
+   | Field | Value |
+   | --- | --- |
+   | PyPI project name | `xenosite-forest` |
+   | Owner | `swamidasslab` |
+   | Repository name | `xenosite-forest` |
+   | Workflow name | `release.yml` |
+   | Environment name | `pypi` |
+
+4. Tag a release (`git tag -a v0.1.0 -m "0.1.0" && git push origin v0.1.0`). The `pypi-publish` job uploads only after tests and build succeed.
+
+For a dry run, register the same publisher on [TestPyPI](https://test.pypi.org/manage/account/publishing/) first and temporarily point the publish action at TestPyPI.
+
+## License
+
+MIT. See [LICENSE](https://github.com/swamidasslab/xenosite-forest/blob/main/LICENSE).

xenosite_forest-0.1.0/README.md

@@ -0,0 +1,147 @@
+# xenosite.forest
+
+Python implementation of **Metabolic Forest**: enumerate explicit metabolite structures from reaction rules, and search pathways that connect a reactant to a putative product.
+
+Site-of-metabolism *prediction* models (epoxidation, quinonation, Phase I, reactivity, and others) are on the web at **[xenosite.org](https://xenosite.org)**. This package is the structure-enumeration engine, not those neural-network models.
+
+If you use this software, please cite the Metabolic Forest paper (DOI and BibTeX below).
+
+## Install
+
+```bash
+uv add xenosite-forest
+```
+
+or
+
+```bash
+pip install xenosite-forest
+```
+
+Optional NetworkX helpers for building a metabolite graph:
+
+```bash
+uv add "xenosite-forest[network]"
+```
+
+Requires **Python 3.10+** and RDKit.
+
+## Quick start
+
+```python
+from rdkit import Chem
+from xenosite.forest import bfs, rules, PhaseOneRS
+
+# Pathway from ethanol to acetaldehyde
+smiles, steps, mols = next(bfs(["CCO", "CC=O"], ruleset="PhaseOneRS"))
+print(smiles)
+print(steps)
+
+# Enumerate hydroxylation products of propane
+for site, products in rules.Hydroxylation().metabolites(Chem.MolFromSmiles("CCC")):
+    print(site, [Chem.MolToSmiles(p) for p in products])
+
+# Named Phase I ruleset
+print(sorted({rule.name for rule in PhaseOneRS}))
+```
+
+A longer walkthrough is in [`examples/tutorial.ipynb`](https://github.com/swamidasslab/xenosite-forest/blob/main/examples/tutorial.ipynb). API notes are in [`docs/usage.md`](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/usage.md). Rulesets and their papers are in [`docs/rulesets.md`](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/rulesets.md).
+
+### Command line
+
+```bash
+xenosite-forest CCO CC=O --ruleset PhaseOneRS --depth 1
+```
+
+Useful flags: `--all-paths`, `--depth N`, `--phase1` (Phase I site strings), `--max N`, `--ruleset NAME`.
+
+## Rulesets and papers
+
+Pass these names to `bfs(..., ruleset=...)` or `load_ruleset(...)`. Full rule lists, Rainbow colors/hex codes, aliases, and BibTeX are in **[`docs/rulesets.md`](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/rulesets.md)**.
+
+| Ruleset | What it enumerates | Matched paper |
+| --- | --- | --- |
+| `PhaseOneRS` | Phase I: SO, UO, DH, HD, RD | Dang et al., Metabolic Rainbow, *JCIM* 2020. DOI [10.1021/acs.jcim.9b00836](https://doi.org/10.1021/acs.jcim.9b00836) |
+| `SO` / `UO` / `DH` / `HD` / `RD` | One Rainbow color each (see hex table in docs) | Same Rainbow paper; Forest rule lists differ slightly for HD/RD/DH |
+| `QuinoneFormationRS` (`QF`) | Quinone, quinone-imine, and quinone-methide structures | Hughes & Swamidass, *Chem. Res. Toxicol.* 2017. DOI [10.1021/acs.chemrestox.6b00385](https://doi.org/10.1021/acs.chemrestox.6b00385) |
+| `Bioactivation` (`BA`) | Quinone, epoxidation, nitroaromatic reduction, thiophene S-oxidation | Hughes et al., *Chem. Res. Toxicol.* 2021. DOI [10.1021/acs.chemrestox.0c00417](https://doi.org/10.1021/acs.chemrestox.0c00417) |
+| `Full` | Complete Metabolic Forest generator (Phase I, conjugations, quinone, tautomerization) | Hughes et al., Metabolic Forest, *JCIM* 2020. DOI [10.1021/acs.jcim.0c00360](https://doi.org/10.1021/acs.jcim.0c00360) |
+
+Rainbow colorblind-safe hex (Wong / Okabe–Ito, closest to the paper figures): **SO** Stable Oxygenation red `#D55E00`, **UO** Unstable Oxygenation orange `#E69F00`, **DH** Dehydrogenation green `#009E73`, **HD** Hydrolysis blue `#56B4E9`, **RD** Reduction purple `#CC79A7`.
+
+Related single-rule papers: epoxidation ([10.1021/acscentsci.5b00131](https://doi.org/10.1021/acscentsci.5b00131)), N-dealkylation ([10.1021/acs.chemrestox.7b00191](https://doi.org/10.1021/acs.chemrestox.7b00191)), UGT glucuronidation ([10.1093/bioinformatics/btw350](https://doi.org/10.1093/bioinformatics/btw350)), glutathione reactivity ([10.1021/acs.chemrestox.5b00017](https://doi.org/10.1021/acs.chemrestox.5b00017)).
+
+## Documentation
+
+- **[Rulesets and papers](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/rulesets.md)** — every built-in ruleset, Rainbow colors, and publication BibTeX
+- **[Usage](https://github.com/swamidasslab/xenosite-forest/blob/main/docs/usage.md)** — public API and pathway search
+- **[Tutorial notebook](https://github.com/swamidasslab/xenosite-forest/blob/main/examples/tutorial.ipynb)** — interactive walkthrough
+- **[xenosite.org](https://xenosite.org)** — XenoSite models for sites of metabolism and reactivity
+- **[Source repository](https://github.com/swamidasslab/xenosite-forest)** — code, issues, and releases
+
+Import the package as `xenosite.forest`. `xenosite` is a PEP 420 namespace, so other `xenosite.*` packages can be installed alongside this one.
+
+## Citation
+
+Please cite Metabolic Forest if you use this package:
+
+Hughes, T. B.; Dang, N. L.; Kumar, A.; Flynn, N. R.; Swamidass, S. J.
+Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites.
+*J. Chem. Inf. Model.* **2020**, *60* (10), 4702–4716.
+**DOI:** [10.1021/acs.jcim.0c00360](https://doi.org/10.1021/acs.jcim.0c00360)
+
+BibTeX (copy and paste):
+
+```bibtex
+@article{Hughes2020MetabolicForest,
+  title = {Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites},
+  author = {Hughes, Tyler B. and Dang, Na Le and Kumar, Ayush and Flynn, Noah R. and Swamidass, S. Joshua},
+  journal = {Journal of Chemical Information and Modeling},
+  volume = {60},
+  number = {10},
+  pages = {4702--4716},
+  year = {2020},
+  doi = {10.1021/acs.jcim.0c00360},
+  url = {https://doi.org/10.1021/acs.jcim.0c00360},
+  publisher = {American Chemical Society}
+}
+```
+
+A machine-readable citation is also in [`CITATION.cff`](https://github.com/swamidasslab/xenosite-forest/blob/main/CITATION.cff).
+
+## Development
+
+```bash
+git clone https://github.com/swamidasslab/xenosite-forest.git
+cd xenosite-forest
+uv sync --extra network --group dev
+uv run pytest -n auto
+```
+
+Versioning comes from git tags via [hatch-vcs](https://github.com/ofek/hatch-vcs) (setuptools-scm). Tag a release as `vX.Y.Z` (for example `v0.1.0`). On that commit the version is `X.Y.Z`. On later untagged commits it becomes the next patch with a dev suffix and short commit, for example `0.1.1.dev3+gabc1234`. Read it at runtime as `xenosite.forest.__version__`.
+
+Pushing a `v*` tag runs [`.github/workflows/release.yml`](https://github.com/swamidasslab/xenosite-forest/blob/main/.github/workflows/release.yml): tests must pass and the resolved version must be a clean `X.Y.Z` before a GitHub Release and PyPI upload. A red tag workflow means do not treat that tag as released. To *block* creating tags unless checks pass, add a GitHub Ruleset on `refs/tags/v*` that requires the `release` / `test` status checks.
+
+### One-time PyPI Trusted Publishing setup
+
+No API token is stored in the repo. CI authenticates with [Trusted Publishing](https://docs.pypi.org/trusted-publishers/) (OIDC).
+
+1. Create the GitHub repo `swamidasslab/xenosite-forest` and push `main`.
+2. GitHub → **Settings → Environments** → create an environment named exactly `pypi` (optional: require reviewers before deploy).
+3. On [PyPI](https://pypi.org/manage/account/publishing/): add a **pending** trusted publisher (project does not need to exist yet):
+
+   | Field | Value |
+   | --- | --- |
+   | PyPI project name | `xenosite-forest` |
+   | Owner | `swamidasslab` |
+   | Repository name | `xenosite-forest` |
+   | Workflow name | `release.yml` |
+   | Environment name | `pypi` |
+
+4. Tag a release (`git tag -a v0.1.0 -m "0.1.0" && git push origin v0.1.0`). The `pypi-publish` job uploads only after tests and build succeed.
+
+For a dry run, register the same publisher on [TestPyPI](https://test.pypi.org/manage/account/publishing/) first and temporarily point the publish action at TestPyPI.
+
+## License
+
+MIT. See [LICENSE](https://github.com/swamidasslab/xenosite-forest/blob/main/LICENSE).