tpixel 0.1.1.dev0__tar.gz

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
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+ name: CI
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+
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+ on:
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+ push:
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+ branches: [main]
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+ pull_request:
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+ branches: [main]
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+
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+ jobs:
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+ test:
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+ runs-on: ${{ matrix.os }}
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+ strategy:
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+ fail-fast: false
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+ matrix:
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+ os: [ubuntu-latest, macos-latest, windows-latest]
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+ python-version: ["3.9", "3.13"]
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+
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+ steps:
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+ - uses: actions/checkout@v4
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+
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+ - name: Set up Python ${{ matrix.python-version }}
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+ uses: actions/setup-python@v5
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+ with:
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+ python-version: ${{ matrix.python-version }}
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+
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+ - name: Install package with dev dependencies
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+ run: pip install ".[dev]"
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+
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+ - name: Run tests
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+ run: pytest -v
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+ name: Publish to PyPI
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+
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+ on:
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+ push:
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+ tags:
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+ - 'v*'
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+ release:
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+ types: [published]
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+ workflow_dispatch:
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+
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+ permissions:
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+ contents: read
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+ id-token: write # Required for trusted publishing
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+
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+ jobs:
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+ build:
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+ name: Build distribution
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+ runs-on: ubuntu-latest
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+ steps:
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+ - uses: actions/checkout@v4
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+ with:
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+ fetch-depth: 0
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+
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+ - name: Set up Python
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+ uses: actions/setup-python@v5
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+ with:
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+ python-version: "3.12"
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+
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+ - name: Install build dependencies
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+ run: python -m pip install --upgrade pip build
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+
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+ - name: Build sdist and wheel
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+ run: python -m build
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+
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+ - name: Upload artifacts
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+ uses: actions/upload-artifact@v4
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+ with:
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+ name: dist
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+ path: dist/
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+
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+ publish-to-pypi:
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+ name: Publish to PyPI
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+ needs: [build]
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+ runs-on: ubuntu-latest
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+ if: always() && needs.build.result == 'success'
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+ environment:
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+ name: pypi
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+ url: https://pypi.org/p/tpixel
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+ permissions:
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+ id-token: write
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+
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+ steps:
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+ - name: Download artifacts
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+ uses: actions/download-artifact@v4
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+ with:
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+ name: dist
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+ path: dist/
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+
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+ - name: Publish to PyPI
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+ uses: pypa/gh-action-pypi-publish@release/v1
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+ # Byte-compiled / optimized / DLL files
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+ __pycache__/
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+ *.py[codz]
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+ *$py.class
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+
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+ # C extensions
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+ *.so
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+
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+ # Distribution / packaging
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+ .Python
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+ build/
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+ develop-eggs/
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+ dist/
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+ downloads/
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+ eggs/
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+ .eggs/
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+ lib/
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+ lib64/
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+ parts/
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+ sdist/
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+ var/
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+ wheels/
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+ share/python-wheels/
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+ *.egg-info/
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+ .installed.cfg
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+ *.egg
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+ MANIFEST
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+
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+ # PyInstaller
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+ # Usually these files are written by a python script from a template
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+ # before PyInstaller builds the exe, so as to inject date/other infos into it.
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+ *.manifest
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+ *.spec
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+
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+ # Installer logs
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+ pip-log.txt
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+ pip-delete-this-directory.txt
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+
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+ # Unit test / coverage reports
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+ htmlcov/
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+ .tox/
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+ .nox/
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+ .coverage
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+ .coverage.*
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+ .cache
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+ nosetests.xml
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+ coverage.xml
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+ *.cover
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+ *.py.cover
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+ .hypothesis/
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+ .pytest_cache/
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+ cover/
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+
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+ # Translations
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+ *.mo
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+ *.pot
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+
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+ # Django stuff:
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+ *.log
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+ local_settings.py
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+ db.sqlite3
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+ db.sqlite3-journal
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+
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+ # Flask stuff:
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+ instance/
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+ .webassets-cache
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+
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+ # Scrapy stuff:
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+ .scrapy
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+
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+ # Sphinx documentation
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+ docs/_build/
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+
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+ # PyBuilder
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+ .pybuilder/
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+ target/
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+
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+ # Jupyter Notebook
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+ .ipynb_checkpoints
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+
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+ # IPython
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+ profile_default/
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+ ipython_config.py
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+
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+ # pyenv
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+ # For a library or package, you might want to ignore these files since the code is
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+ # intended to run in multiple environments; otherwise, check them in:
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+ # .python-version
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+
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+ # pipenv
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+ # According to pypa/pipenv#598, it is recommended to include Pipfile.lock in version control.
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+ # However, in case of collaboration, if having platform-specific dependencies or dependencies
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+ # having no cross-platform support, pipenv may install dependencies that don't work, or not
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+ # install all needed dependencies.
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+ #Pipfile.lock
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+
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+ # UV
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+ # Similar to Pipfile.lock, it is generally recommended to include uv.lock in version control.
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+ # This is especially recommended for binary packages to ensure reproducibility, and is more
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+ # commonly ignored for libraries.
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+ #uv.lock
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+
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+ # poetry
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+ # Similar to Pipfile.lock, it is generally recommended to include poetry.lock in version control.
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+ # This is especially recommended for binary packages to ensure reproducibility, and is more
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+ # commonly ignored for libraries.
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+ # https://python-poetry.org/docs/basic-usage/#commit-your-poetrylock-file-to-version-control
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+ #poetry.lock
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+ #poetry.toml
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+
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+ # pdm
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+ # Similar to Pipfile.lock, it is generally recommended to include pdm.lock in version control.
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+ # pdm recommends including project-wide configuration in pdm.toml, but excluding .pdm-python.
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+ # https://pdm-project.org/en/latest/usage/project/#working-with-version-control
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+ #pdm.lock
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+ #pdm.toml
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+ .pdm-python
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+ .pdm-build/
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+
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+ # pixi
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+ # Similar to Pipfile.lock, it is generally recommended to include pixi.lock in version control.
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+ #pixi.lock
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+ # Pixi creates a virtual environment in the .pixi directory, just like venv module creates one
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+ # in the .venv directory. It is recommended not to include this directory in version control.
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+ .pixi
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+
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+ # PEP 582; used by e.g. github.com/David-OConnor/pyflow and github.com/pdm-project/pdm
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+ __pypackages__/
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+
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+ # Celery stuff
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+ celerybeat-schedule
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+ celerybeat.pid
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+
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+ # SageMath parsed files
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+ *.sage.py
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+
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+ # Environments
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+ .env
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+ .envrc
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+ .venv
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+ env/
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+ venv/
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+ ENV/
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+ env.bak/
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+ venv.bak/
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+
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+ # Spyder project settings
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+ .spyderproject
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+ .spyproject
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+
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+ # Rope project settings
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+ .ropeproject
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+
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+ # mkdocs documentation
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+ /site
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+
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+ # mypy
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+ .mypy_cache/
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+ .dmypy.json
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+ dmypy.json
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+
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+ # Pyre type checker
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+ .pyre/
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+
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+ # pytype static type analyzer
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+ .pytype/
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+
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+ # Cython debug symbols
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+ cython_debug/
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+
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+ # PyCharm
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+ # JetBrains specific template is maintained in a separate JetBrains.gitignore that can
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+ # be found at https://github.com/github/gitignore/blob/main/Global/JetBrains.gitignore
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+ # and can be added to the global gitignore or merged into this file. For a more nuclear
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+ # option (not recommended) you can uncomment the following to ignore the entire idea folder.
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+ #.idea/
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+
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+ # Abstra
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+ # Abstra is an AI-powered process automation framework.
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+ # Ignore directories containing user credentials, local state, and settings.
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+ # Learn more at https://abstra.io/docs
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+ .abstra/
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+
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+ # Visual Studio Code
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+ # Visual Studio Code specific template is maintained in a separate VisualStudioCode.gitignore
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+ # that can be found at https://github.com/github/gitignore/blob/main/Global/VisualStudioCode.gitignore
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+ # and can be added to the global gitignore or merged into this file. However, if you prefer,
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+ # you could uncomment the following to ignore the entire vscode folder
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+ # .vscode/
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+
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+ # Ruff stuff:
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+ .ruff_cache/
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+
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+ # PyPI configuration file
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+ .pypirc
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+
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+ # Cursor
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+ # Cursor is an AI-powered code editor. `.cursorignore` specifies files/directories to
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+ # exclude from AI features like autocomplete and code analysis. Recommended for sensitive data
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+ # refer to https://docs.cursor.com/context/ignore-files
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+ .cursorignore
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+ .cursorindexingignore
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+
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+ # Marimo
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+ marimo/_static/
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+ marimo/_lsp/
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+ __marimo__/
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+ MIT License
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+
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+ Copyright (c) 2026 IAVI-DEV
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+
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+ Permission is hereby granted, free of charge, to any person obtaining a copy
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+ of this software and associated documentation files (the "Software"), to deal
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+ in the Software without restriction, including without limitation the rights
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+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
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+ copies of the Software, and to permit persons to whom the Software is
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+ furnished to do so, subject to the following conditions:
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+
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+ The above copyright notice and this permission notice shall be included in all
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+ copies or substantial portions of the Software.
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+
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+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
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+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
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+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
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+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
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+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
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+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
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+ SOFTWARE.
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+ Metadata-Version: 2.4
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+ Name: tpixel
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+ Version: 0.1.1.dev0
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+ Summary: Pixel-block alignment viewer for hundreds of sequences (Roark-style PIXEL plots)
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+ Author-email: Troy Sincomb <troysincomb@gmail.com>
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+ License: MIT
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+ Keywords: bioinformatics,alignment,pixel,visualization,FASTA,mutation
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+ Classifier: Development Status :: 3 - Alpha
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+ Classifier: Intended Audience :: Science/Research
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+ Classifier: License :: OSI Approved :: MIT License
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+ Classifier: Programming Language :: Python :: 3
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+ Classifier: Programming Language :: Python :: 3.9
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+ Classifier: Programming Language :: Python :: 3.10
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+ Classifier: Programming Language :: Python :: 3.11
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+ Classifier: Programming Language :: Python :: 3.12
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+ Classifier: Programming Language :: Python :: 3.13
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+ Classifier: Programming Language :: Python :: 3.14
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+ Classifier: Topic :: Scientific/Engineering :: Bio-Informatics
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+ Classifier: Topic :: Scientific/Engineering :: Visualization
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+ Requires-Python: >=3.9
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+ Description-Content-Type: text/markdown
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+ License-File: LICENSE
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+ Requires-Dist: matplotlib>=3.5
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+ Requires-Dist: click>=8.0
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+ Provides-Extra: dev
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+ Requires-Dist: pytest>=7.0; extra == "dev"
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+ Dynamic: license-file
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+
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+ # tpixel
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+
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+ Pixel-block alignment viewer for hundreds of sequences. Renders Roark-style PIXEL plots: grey=match, red=substitution, black=gap.
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+
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+ ## Install
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+
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+ ```bash
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+ pip install -e .
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+ ```
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+
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+ ## Usage
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+
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+ ```bash
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+ # Protein alignment (AA mode)
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+ tpixel --fasta examples/env_protein_aligned.fasta -o examples/test_hiv_pixel.png
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+
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+ # Nucleotide alignment (NT mode — auto-detected)
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+ tpixel --fasta examples/env_codon_aligned.fasta -o examples/test_hiv_nt_pixel.png
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+ ```
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+
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+ HIV mode is auto-detected when the alignment contains HxB2 and a `*_ref` sequence. Force with `--hiv` or `--no-hiv`. Nucleotide vs amino-acid mode is auto-detected from sequence content. Force with `--nt` or `--aa`.
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+
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+ ## Examples
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+
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+ Both alignments contain the same 33 sequences (HxB2, animal1_ref, and 31 sample sequences from 7 animals):
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+
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+ | Sequence | Type |
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+ |----------|------|
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+ | HxB2 | Coordinate reference |
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+ | animal1_ref | Parental lineage reference |
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+ | animal1_s1 .. s7 | animal1 samples (7) |
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+ | animal2_s1 .. s5 | animal2 samples (5) |
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+ | animal3_s1 .. s8 | animal3 samples (8) |
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+ | animal4_s1 | animal4 sample (1) |
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+ | animal5_s1 .. s5 | animal5 samples (5) |
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+ | animal6_s1 .. s2 | animal6 samples (2) |
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+ | animal7_s1 .. s3 | animal7 samples (3) |
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+
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+ ### Protein alignment (AA)
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+
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+ `env_protein_aligned.fasta` — 887 columns of HIV-1 Env protein. Each AA = 1 pixel.
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+
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+ ![PIXEL plot — protein](examples/test_hiv_pixel.png)
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+
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+ ### Nucleotide alignment (NT)
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+
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+ `env_codon_aligned.fasta` — 2661 columns of codon-aligned HIV-1 Env DNA. Each NT = 1 pixel. PNGS markers are detected by translating internally and mapped back to NT columns.
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+
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+ ![PIXEL plot — nucleotide](examples/test_hiv_nt_pixel.png)
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+ # tpixel
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+
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+ Pixel-block alignment viewer for hundreds of sequences. Renders Roark-style PIXEL plots: grey=match, red=substitution, black=gap.
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+
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+ ## Install
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+
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+ ```bash
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+ pip install -e .
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+ ```
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+
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+ ## Usage
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+
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+ ```bash
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+ # Protein alignment (AA mode)
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+ tpixel --fasta examples/env_protein_aligned.fasta -o examples/test_hiv_pixel.png
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+
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+ # Nucleotide alignment (NT mode — auto-detected)
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+ tpixel --fasta examples/env_codon_aligned.fasta -o examples/test_hiv_nt_pixel.png
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+ ```
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+
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+ HIV mode is auto-detected when the alignment contains HxB2 and a `*_ref` sequence. Force with `--hiv` or `--no-hiv`. Nucleotide vs amino-acid mode is auto-detected from sequence content. Force with `--nt` or `--aa`.
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+
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+ ## Examples
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+
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+ Both alignments contain the same 33 sequences (HxB2, animal1_ref, and 31 sample sequences from 7 animals):
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+
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+ | Sequence | Type |
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+ |----------|------|
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+ | HxB2 | Coordinate reference |
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+ | animal1_ref | Parental lineage reference |
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+ | animal1_s1 .. s7 | animal1 samples (7) |
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+ | animal2_s1 .. s5 | animal2 samples (5) |
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+ | animal3_s1 .. s8 | animal3 samples (8) |
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+ | animal4_s1 | animal4 sample (1) |
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+ | animal5_s1 .. s5 | animal5 samples (5) |
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+ | animal6_s1 .. s2 | animal6 samples (2) |
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+ | animal7_s1 .. s3 | animal7 samples (3) |
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+
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+ ### Protein alignment (AA)
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+
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+ `env_protein_aligned.fasta` — 887 columns of HIV-1 Env protein. Each AA = 1 pixel.
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+
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+ ![PIXEL plot — protein](examples/test_hiv_pixel.png)
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+
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+ ### Nucleotide alignment (NT)
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+
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+ `env_codon_aligned.fasta` — 2661 columns of codon-aligned HIV-1 Env DNA. Each NT = 1 pixel. PNGS markers are detected by translating internally and mapped back to NT columns.
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+
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+ ![PIXEL plot — nucleotide](examples/test_hiv_nt_pixel.png)