segprobe 0.1.0__tar.gz

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+ cff-version: 1.2.0
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+ message: "If you use SegProbe in your research, please cite this software."
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+ title: "SegProbe"
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+ type: software
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+ version: 0.1.0
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+ authors:
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+ - family-names: "Ebou"
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+ given-names: "Elhaj Samitt"
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+ orcid: "https://orcid.org/0009-0004-5324-2385"
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+ repository-code: "https://github.com/hajteyib/segprobe"
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+ license: "Apache-2.0"
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+ keywords:
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+ - medical image segmentation
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+ - prompt evaluation
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+ - interactive segmentation
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+ - bounding boxes
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+ - reproducibility
segprobe-0.1.0/LICENSE ADDED
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+ include CITATION.cff
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+ recursive-include examples *.py
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+ Metadata-Version: 2.4
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+ Name: segprobe
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+ Version: 0.1.0
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+ Summary: Reproducible, model-agnostic prompt evaluation for medical segmentation.
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+ Author: Elhaj Samitt Ebou
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+ License-Expression: Apache-2.0
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+ Project-URL: Repository, https://github.com/hajteyib/segprobe
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+ Project-URL: Issues, https://github.com/hajteyib/segprobe/issues
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+ Classifier: Development Status :: 3 - Alpha
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+ Classifier: Programming Language :: Python :: 3
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+ Classifier: Programming Language :: Python :: 3.10
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+ Classifier: Programming Language :: Python :: 3.11
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+ Classifier: Programming Language :: Python :: 3.12
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+ Classifier: Programming Language :: Python :: 3.13
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+ Classifier: Topic :: Scientific/Engineering :: Medical Science Apps.
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+ Requires-Python: >=3.10
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+ Description-Content-Type: text/markdown
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+ License-File: LICENSE
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+ Requires-Dist: numpy>=1.23
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+ Provides-Extra: dev
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+ Requires-Dist: build>=1.2; extra == "dev"
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+ Requires-Dist: pytest>=8; extra == "dev"
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+ Requires-Dist: ruff>=0.6; extra == "dev"
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+ Dynamic: license-file
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+
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+ # SegProbe
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+
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+ SegProbe makes box-prompt experiments reproducible across medical image
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+ segmentation models. It generates prompt protocols, records the manual effort,
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+ and evaluates the resulting masks through one small API.
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+
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+ ![SegProbe overview](https://raw.githubusercontent.com/hajteyib/segprobe/main/docs/assets/segprobe-overview.png)
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+
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+ It started as code i used while testing MedSAM. i wanted to answer simple
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+ questions without rewriting the evaluation each time:
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+
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+ - How many boxes must be drawn manually?
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+ - What happens if boxes are sparse, larger, or slightly misplaced?
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+ - Can the same protocol be compared across different models?
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+
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+ SegProbe has one runtime dependency: NumPy. It does not download a model or a
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+ dataset.
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+
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+ ## Install
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+
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+ ```bash
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+ python -m pip install segprobe
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+ ```
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+
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+ For development, install it from a local clone:
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+
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+ ```bash
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+ python -m pip install -e .
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+ ```
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+
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+ ## Quick start
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+
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+ ```python
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+ from segprobe import evaluate, sparse_boxes
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+
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+ plan = sparse_boxes(target_mask, every=3, padding=5)
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+
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+ def predictor(volume, z_index, box_xyxy):
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+ image_slice = volume[z_index]
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+ return my_model.predict(image_slice, box=box_xyxy)
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+
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+ result = evaluate(predictor, image_volume, target_mask, plan)
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+
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+ print(result.dice)
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+ print(result.manual_boxes)
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+ print(result.generated_boxes)
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+ ```
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+
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+ The `predictor` function is the only model-specific part. It can call MedSAM,
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+ SAM2, nnInteractive, or your own slice-based model.
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+
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+ ## Prompt protocols
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+
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+ ```python
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+ from segprobe import global_box, slice_boxes, sparse_boxes
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+
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+ dense = slice_boxes(mask, padding=5)
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+ global_prompt = global_box(mask, padding=5)
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+ sparse = sparse_boxes(mask, every=3, padding=5)
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+ ```
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+
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+ | Protocol | Manual effort | Boxes sent to the model |
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+ | --- | ---: | --- |
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+ | `slice_boxes` | one per positive slice | one manual box on each slice |
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+ | `global_box` | one per volume | the same box reused on all positive slices |
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+ | `sparse_boxes` | one every N positive slices, plus the last | manual anchors and interpolated boxes |
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+
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+ Each plan reports `manual_boxes`, `generated_boxes`, and `manual_fraction`.
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+ `plan.to_dict()` returns plain Python values ready for JSON.
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+
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+ ### Sparse prompts
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+
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+ Here, only five boxes are drawn manually. The other fifteen are interpolated.
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+
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+ ![Sparse box interpolation through a CT volume](https://raw.githubusercontent.com/hajteyib/segprobe/main/docs/assets/sparse-prompts.gif)
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+
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+ Blue boxes are manual anchors. Orange dashed boxes are generated between them.
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+ The green line is the reference-mask contour.
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+
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+ ## Prompt robustness
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+
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+ Box size and placement can change a promptable model's result. SegProbe can add
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+ padding or apply deterministic perturbations, so the same stress test can be
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+ run again with the same seed.
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+
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+ ```python
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+ from segprobe import jitter_plan
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+
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+ noisy = jitter_plan(
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+ dense,
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+ max_translate=5,
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+ max_expand=10,
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+ seed=42,
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+ sample_key="case-001",
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+ )
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+ ```
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+
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+ ![Box size, translation, and expansion](https://raw.githubusercontent.com/hajteyib/segprobe/main/docs/assets/prompt-geometry.gif)
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+
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+ ## Public MedSAM example
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+
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+ [`examples/medsam_lidc.py`](examples/medsam_lidc.py) connects SegProbe to the
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+ official [MedSAM ViT-B model](https://github.com/bowang-lab/MedSAM). It expects
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+ one folder per case containing
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+ `image.nii.gz` and `mask.nii.gz`.
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+
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+ Run it from an environment where MedSAM, PyTorch, NiBabel, and scikit-image are
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+ available:
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+
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+ ```bash
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+ python examples/medsam_lidc.py \
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+ --cases-root /path/to/lidc_crops \
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+ --one-per-patient \
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+ --limit 5 \
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+ --medsam-repo /path/to/MedSAM \
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+ --checkpoint /path/to/medsam_vit_b.pth \
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+ --output-dir medsam_results \
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+ --device cpu
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+ ```
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+
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+ The script saves `results.csv` and `results.json` after every protocol. Running
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+ the same command again resumes from the saved results.
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+
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+ We used it for a small public check with five LIDC-IDRI nodules, one per
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+ patient. The run used the official MedSAM checkpoint, no private fine-tuning,
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+ no postprocessing, and an oracle positive z-range from the reference mask.
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+
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+ ### Prompt density with padding=5
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+
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+ | Protocol | Mean manual boxes | Mean generated boxes | Mean Dice ± SD |
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+ | --- | ---: | ---: | ---: |
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+ | Global | 1.0 | 16.0 | 0.372 ± 0.173 |
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+ | Sparse every 5 slices | 4.4 | 12.6 | 0.515 ± 0.267 |
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+ | Sparse every 3 slices | 7.0 | 10.0 | 0.508 ± 0.270 |
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+ | Sparse every 2 slices | 9.2 | 7.8 | 0.510 ± 0.270 |
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+ | Dense | 17.0 | 0.0 | 0.511 ± 0.271 |
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+
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+ In this small run, sparse prompting every five slices used about 74% fewer
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+ manual boxes than dense prompting, with nearly the same mean Dice.
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+
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+ ### Dense prompt geometry
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+
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+ | Box | Mean Dice ± SD |
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+ | --- | ---: |
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+ | Tight, `padding=0` | 0.843 ± 0.031 |
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+ | `padding=5` | 0.511 ± 0.271 |
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+ | Large, `padding=10` | 0.310 ± 0.224 |
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+ | `padding=5` with deterministic jitter | 0.363 ± 0.263 |
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+
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+ The tight box is derived directly from the reference mask, so it is a strong
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+ oracle prompt. These five cases are a reproducibility example, not a model
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+ comparison or a clinical result.
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+
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+ ## Inputs and image formats
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+
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+ SegProbe works with arrays, not a specific medical file format. CT, MRI, PET,
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+ and other 3D images can use the same API after they are loaded into NumPy.
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+
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+ - The mask must have shape `(z, y, x)`.
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+ - The image must start with the same dimensions: `(z, y, x)` or
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+ `(z, y, x, channels)`.
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+ - Boxes use `(x_min, y_min, x_max, y_max)`, with exclusive maximum coordinates.
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+
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+ NIfTI, DICOM, NRRD, and other files can be loaded with tools such as NiBabel,
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+ SimpleITK, or pydicom. File loading stays outside SegProbe so the core package
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+ remains small and does not impose an imaging stack.
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+
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+ ## Evaluation output
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+
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+ `evaluate` returns the predicted 3D mask together with:
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+
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+ - Dice and IoU;
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+ - target and prediction voxel counts;
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+ - manual and generated box counts;
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+ - number of prompted slices.
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+
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+ The scalar values are available with `result.to_dict()` for a CSV or JSON
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+ report.
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+
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+ ## Scope
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+
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+ The current prompt generators use a reference mask. They are made for
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+ controlled oracle-prompt evaluation, not automatic lesion localization.
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+
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+ Only reference-positive slices receive a box, so the positive z-range is known.
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+ Results should be described as prompt-effort or prompt-robustness experiments,
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+ not end-to-end detection results.
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+
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+ The manual-box count is an effort proxy. It is not a measurement of annotation
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+ time. SegProbe is a research evaluation tool and is not intended for clinical
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+ decision-making.
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+
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+ ## Development
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+
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+ ```bash
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+ python -m pip install -e ".[dev]"
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+ ruff check .
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+ pytest -q
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+ python -m build
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+ ```
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+
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+ Tests use small synthetic masks. They do not download images, checkpoints, or
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+ patient data.
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+
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+ ## Citation
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+
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+ If SegProbe supports your work, please cite the software using
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+ [`CITATION.cff`](CITATION.cff).
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+
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+ The images in this README use a cropped, windowed, and annotated case from the
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+ public [LIDC-IDRI collection](https://www.cancerimagingarchive.net/collection/lidc-idri/):
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+
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+ > Armato III, S. G., McLennan, G., Bidaut, L., et al. (2015). Data From
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+ > LIDC-IDRI. The Cancer Imaging Archive.
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+ > [https://doi.org/10.7937/K9/TCIA.2015.LO9QL9SX](https://doi.org/10.7937/K9/TCIA.2015.LO9QL9SX)
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+
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+ LIDC-IDRI is available under the
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+ [Creative Commons Attribution 3.0 license](https://creativecommons.org/licenses/by/3.0/).
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+
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+ ## License
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+
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+ SegProbe is released under the [Apache-2.0 license](LICENSE).
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+ # SegProbe
2
+
3
+ SegProbe makes box-prompt experiments reproducible across medical image
4
+ segmentation models. It generates prompt protocols, records the manual effort,
5
+ and evaluates the resulting masks through one small API.
6
+
7
+ ![SegProbe overview](https://raw.githubusercontent.com/hajteyib/segprobe/main/docs/assets/segprobe-overview.png)
8
+
9
+ It started as code i used while testing MedSAM. i wanted to answer simple
10
+ questions without rewriting the evaluation each time:
11
+
12
+ - How many boxes must be drawn manually?
13
+ - What happens if boxes are sparse, larger, or slightly misplaced?
14
+ - Can the same protocol be compared across different models?
15
+
16
+ SegProbe has one runtime dependency: NumPy. It does not download a model or a
17
+ dataset.
18
+
19
+ ## Install
20
+
21
+ ```bash
22
+ python -m pip install segprobe
23
+ ```
24
+
25
+ For development, install it from a local clone:
26
+
27
+ ```bash
28
+ python -m pip install -e .
29
+ ```
30
+
31
+ ## Quick start
32
+
33
+ ```python
34
+ from segprobe import evaluate, sparse_boxes
35
+
36
+ plan = sparse_boxes(target_mask, every=3, padding=5)
37
+
38
+ def predictor(volume, z_index, box_xyxy):
39
+ image_slice = volume[z_index]
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+ return my_model.predict(image_slice, box=box_xyxy)
41
+
42
+ result = evaluate(predictor, image_volume, target_mask, plan)
43
+
44
+ print(result.dice)
45
+ print(result.manual_boxes)
46
+ print(result.generated_boxes)
47
+ ```
48
+
49
+ The `predictor` function is the only model-specific part. It can call MedSAM,
50
+ SAM2, nnInteractive, or your own slice-based model.
51
+
52
+ ## Prompt protocols
53
+
54
+ ```python
55
+ from segprobe import global_box, slice_boxes, sparse_boxes
56
+
57
+ dense = slice_boxes(mask, padding=5)
58
+ global_prompt = global_box(mask, padding=5)
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+ sparse = sparse_boxes(mask, every=3, padding=5)
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+ ```
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+
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+ | Protocol | Manual effort | Boxes sent to the model |
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+ | --- | ---: | --- |
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+ | `slice_boxes` | one per positive slice | one manual box on each slice |
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+ | `global_box` | one per volume | the same box reused on all positive slices |
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+ | `sparse_boxes` | one every N positive slices, plus the last | manual anchors and interpolated boxes |
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+
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+ Each plan reports `manual_boxes`, `generated_boxes`, and `manual_fraction`.
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+ `plan.to_dict()` returns plain Python values ready for JSON.
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+
71
+ ### Sparse prompts
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+
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+ Here, only five boxes are drawn manually. The other fifteen are interpolated.
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+
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+ ![Sparse box interpolation through a CT volume](https://raw.githubusercontent.com/hajteyib/segprobe/main/docs/assets/sparse-prompts.gif)
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+
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+ Blue boxes are manual anchors. Orange dashed boxes are generated between them.
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+ The green line is the reference-mask contour.
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+
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+ ## Prompt robustness
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+
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+ Box size and placement can change a promptable model's result. SegProbe can add
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+ padding or apply deterministic perturbations, so the same stress test can be
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+ run again with the same seed.
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+
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+ ```python
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+ from segprobe import jitter_plan
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+
89
+ noisy = jitter_plan(
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+ dense,
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+ max_translate=5,
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+ max_expand=10,
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+ seed=42,
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+ sample_key="case-001",
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+ )
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+ ```
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+
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+ ![Box size, translation, and expansion](https://raw.githubusercontent.com/hajteyib/segprobe/main/docs/assets/prompt-geometry.gif)
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+
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+ ## Public MedSAM example
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+
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+ [`examples/medsam_lidc.py`](examples/medsam_lidc.py) connects SegProbe to the
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+ official [MedSAM ViT-B model](https://github.com/bowang-lab/MedSAM). It expects
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+ one folder per case containing
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+ `image.nii.gz` and `mask.nii.gz`.
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+
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+ Run it from an environment where MedSAM, PyTorch, NiBabel, and scikit-image are
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+ available:
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+
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+ ```bash
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+ python examples/medsam_lidc.py \
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+ --cases-root /path/to/lidc_crops \
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+ --one-per-patient \
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+ --limit 5 \
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+ --medsam-repo /path/to/MedSAM \
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+ --checkpoint /path/to/medsam_vit_b.pth \
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+ --output-dir medsam_results \
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+ --device cpu
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+ ```
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+
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+ The script saves `results.csv` and `results.json` after every protocol. Running
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+ the same command again resumes from the saved results.
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+
124
+ We used it for a small public check with five LIDC-IDRI nodules, one per
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+ patient. The run used the official MedSAM checkpoint, no private fine-tuning,
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+ no postprocessing, and an oracle positive z-range from the reference mask.
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+
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+ ### Prompt density with padding=5
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+
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+ | Protocol | Mean manual boxes | Mean generated boxes | Mean Dice ± SD |
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+ | --- | ---: | ---: | ---: |
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+ | Global | 1.0 | 16.0 | 0.372 ± 0.173 |
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+ | Sparse every 5 slices | 4.4 | 12.6 | 0.515 ± 0.267 |
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+ | Sparse every 3 slices | 7.0 | 10.0 | 0.508 ± 0.270 |
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+ | Sparse every 2 slices | 9.2 | 7.8 | 0.510 ± 0.270 |
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+ | Dense | 17.0 | 0.0 | 0.511 ± 0.271 |
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+
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+ In this small run, sparse prompting every five slices used about 74% fewer
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+ manual boxes than dense prompting, with nearly the same mean Dice.
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+
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+ ### Dense prompt geometry
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+
143
+ | Box | Mean Dice ± SD |
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+ | --- | ---: |
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+ | Tight, `padding=0` | 0.843 ± 0.031 |
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+ | `padding=5` | 0.511 ± 0.271 |
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+ | Large, `padding=10` | 0.310 ± 0.224 |
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+ | `padding=5` with deterministic jitter | 0.363 ± 0.263 |
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+
150
+ The tight box is derived directly from the reference mask, so it is a strong
151
+ oracle prompt. These five cases are a reproducibility example, not a model
152
+ comparison or a clinical result.
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+
154
+ ## Inputs and image formats
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+
156
+ SegProbe works with arrays, not a specific medical file format. CT, MRI, PET,
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+ and other 3D images can use the same API after they are loaded into NumPy.
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+
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+ - The mask must have shape `(z, y, x)`.
160
+ - The image must start with the same dimensions: `(z, y, x)` or
161
+ `(z, y, x, channels)`.
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+ - Boxes use `(x_min, y_min, x_max, y_max)`, with exclusive maximum coordinates.
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+
164
+ NIfTI, DICOM, NRRD, and other files can be loaded with tools such as NiBabel,
165
+ SimpleITK, or pydicom. File loading stays outside SegProbe so the core package
166
+ remains small and does not impose an imaging stack.
167
+
168
+ ## Evaluation output
169
+
170
+ `evaluate` returns the predicted 3D mask together with:
171
+
172
+ - Dice and IoU;
173
+ - target and prediction voxel counts;
174
+ - manual and generated box counts;
175
+ - number of prompted slices.
176
+
177
+ The scalar values are available with `result.to_dict()` for a CSV or JSON
178
+ report.
179
+
180
+ ## Scope
181
+
182
+ The current prompt generators use a reference mask. They are made for
183
+ controlled oracle-prompt evaluation, not automatic lesion localization.
184
+
185
+ Only reference-positive slices receive a box, so the positive z-range is known.
186
+ Results should be described as prompt-effort or prompt-robustness experiments,
187
+ not end-to-end detection results.
188
+
189
+ The manual-box count is an effort proxy. It is not a measurement of annotation
190
+ time. SegProbe is a research evaluation tool and is not intended for clinical
191
+ decision-making.
192
+
193
+ ## Development
194
+
195
+ ```bash
196
+ python -m pip install -e ".[dev]"
197
+ ruff check .
198
+ pytest -q
199
+ python -m build
200
+ ```
201
+
202
+ Tests use small synthetic masks. They do not download images, checkpoints, or
203
+ patient data.
204
+
205
+ ## Citation
206
+
207
+ If SegProbe supports your work, please cite the software using
208
+ [`CITATION.cff`](CITATION.cff).
209
+
210
+ The images in this README use a cropped, windowed, and annotated case from the
211
+ public [LIDC-IDRI collection](https://www.cancerimagingarchive.net/collection/lidc-idri/):
212
+
213
+ > Armato III, S. G., McLennan, G., Bidaut, L., et al. (2015). Data From
214
+ > LIDC-IDRI. The Cancer Imaging Archive.
215
+ > [https://doi.org/10.7937/K9/TCIA.2015.LO9QL9SX](https://doi.org/10.7937/K9/TCIA.2015.LO9QL9SX)
216
+
217
+ LIDC-IDRI is available under the
218
+ [Creative Commons Attribution 3.0 license](https://creativecommons.org/licenses/by/3.0/).
219
+
220
+ ## License
221
+
222
+ SegProbe is released under the [Apache-2.0 license](LICENSE).