pen-stack 7.1.1__tar.gz → 7.1.2__tar.gz

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (565) hide show
  1. {pen_stack-7.1.1 → pen_stack-7.1.2}/CHANGELOG.md +17 -0
  2. {pen_stack-7.1.1 → pen_stack-7.1.2}/CITATION.cff +2 -2
  3. {pen_stack-7.1.1 → pen_stack-7.1.2}/PKG-INFO +1 -1
  4. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/__init__.py +1 -1
  5. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/rag/embed.py +19 -0
  6. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/rag/ground.py +3 -2
  7. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/rag/retrieve.py +2 -2
  8. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/web/llm.py +7 -4
  9. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/web/llm_provider.py +30 -10
  10. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack.egg-info/PKG-INFO +1 -1
  11. {pen_stack-7.1.1 → pen_stack-7.1.2}/pyproject.toml +1 -1
  12. {pen_stack-7.1.1 → pen_stack-7.1.2}/LICENSE +0 -0
  13. {pen_stack-7.1.1 → pen_stack-7.1.2}/MANIFEST.in +0 -0
  14. {pen_stack-7.1.1 → pen_stack-7.1.2}/README.md +0 -0
  15. {pen_stack-7.1.1 → pen_stack-7.1.2}/bench/run.py +0 -0
  16. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_grounding/README.md +0 -0
  17. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_grounding/SHA256SUMS +0 -0
  18. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_headtohead/README.md +0 -0
  19. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_routing/README.md +0 -0
  20. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_routing/SHA256SUMS +0 -0
  21. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_safety/README.md +0 -0
  22. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/chat_safety/SHA256SUMS +0 -0
  23. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/delivery/SHA256SUMS +0 -0
  24. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_bench/LEADERBOARD.md +0 -0
  25. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_bench/README.md +0 -0
  26. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_bench/SHA256SUMS +0 -0
  27. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_bench/SUBMISSIONS.md +0 -0
  28. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_bench/tasks.yaml +0 -0
  29. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_challenge/README.md +0 -0
  30. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/genome_writing_challenge/SUBMISSIONS.md +0 -0
  31. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/loop/SHA256SUMS +0 -0
  32. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/offtarget/SHA256SUMS +0 -0
  33. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/oracle/SHA256SUMS +0 -0
  34. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/position_effect/README.md +0 -0
  35. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/position_effect/SHA256SUMS +0 -0
  36. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/verify/SHA256SUMS +0 -0
  37. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/writer_efficiency/README.md +0 -0
  38. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/writer_efficiency/SHA256SUMS +0 -0
  39. {pen_stack-7.1.1 → pen_stack-7.1.2}/benchmarks/writespec/SHA256SUMS +0 -0
  40. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/aav_serotype_tropism.yaml +0 -0
  41. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/antipeg.yaml +0 -0
  42. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/atlas_families.yaml +0 -0
  43. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/bridge_offtarget_profile.yaml +0 -0
  44. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/calibration/preexisting_nab_independent.yaml +0 -0
  45. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/capsid_epitope_oracle.yaml +0 -0
  46. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/capsid_sequences.fasta +0 -0
  47. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/cargo_polish.yaml +0 -0
  48. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/cell_types.yaml +0 -0
  49. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/datasets.yaml +0 -0
  50. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/delivery_constraints.yaml +0 -0
  51. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/delivery_rules.yaml +0 -0
  52. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/delivery_vehicles.yaml +0 -0
  53. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/expression/modifiers.yaml +0 -0
  54. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/expression/promoters.yaml +0 -0
  55. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/gates_v3.yaml +0 -0
  56. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/genotoxicity_oracle.yaml +0 -0
  57. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/gsh_validated_heldout.yaml +0 -0
  58. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/intent_weights.yaml +0 -0
  59. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/known_unknowns.yaml +0 -0
  60. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/llm.yaml +0 -0
  61. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/metric_guide.yaml +0 -0
  62. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/mhc_epitope_oracle.yaml +0 -0
  63. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/monitor_queries.yaml +0 -0
  64. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/oracles/execution.yaml +0 -0
  65. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/oracles/reliability.yaml +0 -0
  66. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/oracles/scope_cards.yaml +0 -0
  67. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/rules/delivery.yaml +0 -0
  68. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/rules/fold.yaml +0 -0
  69. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/rules/multiplex.yaml +0 -0
  70. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/rules/payload.yaml +0 -0
  71. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/rules/reachability.yaml +0 -0
  72. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/safety/hazard_registry.yaml +0 -0
  73. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/safety/policy.yaml +0 -0
  74. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/safety/probes.yaml +0 -0
  75. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/score_axes.yaml +0 -0
  76. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/seroprevalence.yaml +0 -0
  77. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/target_sites.yaml +0 -0
  78. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/universe_crosswalk.yaml +0 -0
  79. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/write_types.yaml +0 -0
  80. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/writer_sequences.fasta +0 -0
  81. {pen_stack-7.1.1 → pen_stack-7.1.2}/configs/wtkb_curated.yaml +0 -0
  82. {pen_stack-7.1.1 → pen_stack-7.1.2}/data/curated/bridge_offtarget_energetics.json +0 -0
  83. {pen_stack-7.1.1 → pen_stack-7.1.2}/data/curated/bridge_offtarget_profile_measured.parquet +0 -0
  84. {pen_stack-7.1.1 → pen_stack-7.1.2}/data/curated/gene_coords.parquet +0 -0
  85. {pen_stack-7.1.1 → pen_stack-7.1.2}/data/curated/unified_editor_universe.parquet +0 -0
  86. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/BACKLOG.md +0 -0
  87. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/DEPLOY.md +0 -0
  88. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/INFRA.md +0 -0
  89. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/MCP.md +0 -0
  90. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/RELEASING.md +0 -0
  91. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/REPRO.md +0 -0
  92. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/STABILITY.md +0 -0
  93. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/agent.md +0 -0
  94. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/alphagenome_feasibility.md +0 -0
  95. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/autonomy.md +0 -0
  96. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/benchmark_circularity.md +0 -0
  97. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/biosecurity.md +0 -0
  98. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/build_interface.md +0 -0
  99. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/cards/atlas.md +0 -0
  100. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/cards/durability.md +0 -0
  101. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/cards/offtarget_data.md +0 -0
  102. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/cards/position_effect_data.md +0 -0
  103. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/cards/safety.md +0 -0
  104. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/cards/writer_efficiency_data.md +0 -0
  105. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/challenge.md +0 -0
  106. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/closed_loop.md +0 -0
  107. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/co_scientist.md +0 -0
  108. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/co_scientist_loop.md +0 -0
  109. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/delivery.md +0 -0
  110. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/delivery_immunology.md +0 -0
  111. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/delivery_recommender.md +0 -0
  112. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/digital_twin.md +0 -0
  113. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/dissemination.md +0 -0
  114. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/environment.md +0 -0
  115. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/experiment_design.md +0 -0
  116. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/generative_design.md +0 -0
  117. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/immune_profiler.md +0 -0
  118. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/index.md +0 -0
  119. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/integrations.md +0 -0
  120. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/live_oracles.md +0 -0
  121. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/mechanistic_constraints.md +0 -0
  122. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/offtarget.md +0 -0
  123. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/oracle_mesh.md +0 -0
  124. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/oracles.md +0 -0
  125. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/position_effect.md +0 -0
  126. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/positioning.md +0 -0
  127. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/private_data_formats.md +0 -0
  128. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/quickstart.md +0 -0
  129. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/responsible_use.md +0 -0
  130. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/rule_spec.md +0 -0
  131. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/rules.md +0 -0
  132. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/scope.md +0 -0
  133. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/scorecard.md +0 -0
  134. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/tpe_bench.md +0 -0
  135. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/tutorials/compare-families.md +0 -0
  136. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/tutorials/score-deliverability.md +0 -0
  137. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/tutorials/where-can-i-write.md +0 -0
  138. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/tutorials/which-writer-reaches-locus.md +0 -0
  139. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/uncertainty.md +0 -0
  140. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/verify.md +0 -0
  141. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/verify_service.md +0 -0
  142. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/world_model.md +0 -0
  143. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/writer_efficiency.md +0 -0
  144. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/writer_verification.md +0 -0
  145. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/writespec_bench.md +0 -0
  146. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/writespec_profile.md +0 -0
  147. {pen_stack-7.1.1 → pen_stack-7.1.2}/docs/wtkb.md +0 -0
  148. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/_resources.py +0 -0
  149. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/active/__init__.py +0 -0
  150. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/active/acquire.py +0 -0
  151. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/active/brains.py +0 -0
  152. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/active/campaign.py +0 -0
  153. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/active/design.py +0 -0
  154. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/active/validate.py +0 -0
  155. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/adapt/__init__.py +0 -0
  156. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/adapt/finetune.py +0 -0
  157. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/adapt/ingest.py +0 -0
  158. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/adapt/pipeline.py +0 -0
  159. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/adapt/recalibrate.py +0 -0
  160. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/adapt/report.py +0 -0
  161. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/__init__.py +0 -0
  162. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/cite.py +0 -0
  163. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/co_scientist.py +0 -0
  164. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/epistemic.py +0 -0
  165. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/guardrails.py +0 -0
  166. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/mcp_server.py +0 -0
  167. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/orchestrator.py +0 -0
  168. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/orchestrator_live.py +0 -0
  169. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/pen_agent.py +0 -0
  170. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/scope.py +0 -0
  171. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/agent/tools.py +0 -0
  172. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/api/__init__.py +0 -0
  173. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/api/manifest.py +0 -0
  174. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/__init__.py +0 -0
  175. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/build_wtkb.py +0 -0
  176. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/crosslink.py +0 -0
  177. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/expand.py +0 -0
  178. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/guide_design.py +0 -0
  179. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/schema.py +0 -0
  180. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/scorecard.py +0 -0
  181. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/universe.py +0 -0
  182. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/variant_propose.py +0 -0
  183. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/writer_efficiency.py +0 -0
  184. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/writer_predict.py +0 -0
  185. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/writer_recommend.py +0 -0
  186. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/atlas/writer_verify.py +0 -0
  187. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/__init__.py +0 -0
  188. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/activity.py +0 -0
  189. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/cli.py +0 -0
  190. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/fold_qc.py +0 -0
  191. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/guide_qc.py +0 -0
  192. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/ingest.py +0 -0
  193. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/offtarget.py +0 -0
  194. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/offtarget_energetics.py +0 -0
  195. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/ortholog_screen.py +0 -0
  196. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/bridge/pipeline.py +0 -0
  197. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/build/__init__.py +0 -0
  198. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/build/cloudlab.py +0 -0
  199. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/build/ingest.py +0 -0
  200. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/build/protocol.py +0 -0
  201. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/build/simlab.py +0 -0
  202. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/cli.py +0 -0
  203. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/data/__init__.py +0 -0
  204. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/data/encode.py +0 -0
  205. {pen_stack-7.1.1 → pen_stack-7.1.2}/pen_stack/data/genome.py +0 -0
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  483. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_chat.yaml +0 -0
  484. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_cite.yaml +0 -0
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  487. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_cosci2.yaml +0 -0
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  494. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_env.yaml +0 -0
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  513. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_mcp.yaml +0 -0
  514. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_mech.yaml +0 -0
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  518. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_openapi.yaml +0 -0
  519. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_oracle.yaml +0 -0
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  523. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_peg.yaml +0 -0
  524. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_penchat.yaml +0 -0
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  536. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_uq.yaml +0 -0
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  538. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_vcell.yaml +0 -0
  539. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_verify.yaml +0 -0
  540. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_writer.yaml +0 -0
  541. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_writespec.yaml +0 -0
  542. {pen_stack-7.1.1 → pen_stack-7.1.2}/prereg/ws_wv.yaml +0 -0
  543. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/build_capsid_fitness.py +0 -0
  544. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/build_rag_corpus.py +0 -0
  545. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/calibrate_immune_axes.py +0 -0
  546. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/fetch_licensed_sources.py +0 -0
  547. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/offtarget_chromatin_incremental.py +0 -0
  548. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/offtarget_chromatin_matched.py +0 -0
  549. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/offtarget_chromatin_validation.py +0 -0
  550. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_build_atlas.py +0 -0
  551. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_build_durability.py +0 -0
  552. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_build_position_effect.py +0 -0
  553. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_build_writer_eff.py +0 -0
  554. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_export_tracks.py +0 -0
  555. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_safety_concordance.py +0 -0
  556. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_train_safety.py +0 -0
  557. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p1_validation_report.py +0 -0
  558. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p2_build_atlas.py +0 -0
  559. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p3_benchmark_report.py +0 -0
  560. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p4_genome_scan.py +0 -0
  561. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p52_build_genotox_oracle.py +0 -0
  562. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/p53_build_epitope_oracle.py +0 -0
  563. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/ws_b_report.py +0 -0
  564. {pen_stack-7.1.1 → pen_stack-7.1.2}/scripts/ws_c_report.py +0 -0
  565. {pen_stack-7.1.1 → pen_stack-7.1.2}/setup.cfg +0 -0
@@ -3,6 +3,23 @@
3
3
  All notable changes to PEN-STACK are documented here. This file follows
4
4
  [Keep a Changelog](https://keepachangelog.com/).
5
5
 
6
+ ## [7.1.2] - 2026-06-25 - PEN-CHAT: chat-response latency fix
7
+
8
+ ### Fixed
9
+ - Chat response time was unnecessarily high because every General-lane request paid for an Ollama embedding
10
+ round-trip on the query side, and the LLM call ran with a generous 150 s timeout / 450-token cap suited to the
11
+ engine-grounded design lane, not a textbook answer. Three minimal changes, no behaviour change for the grounded
12
+ lanes:
13
+ - `pen_stack/rag/embed.py` adds an LRU-cached `embed_query()` (256 entries) so a repeated phrasing skips the
14
+ embedder; `pen_stack/rag/retrieve.py` uses it.
15
+ - `pen_stack/web/llm_provider.py` now accepts `kind="general"`, which selects `PEN_STACK_LLM_TIMEOUT_GENERAL`
16
+ (45 s default, was 150 s) and `OLLAMA_NUM_PREDICT_GENERAL` / `NEMOTRON_MAX_TOKENS_GENERAL` (280 / 400, was
17
+ 450 / 700). The default-kind path used by the engine-grounded design / explain / meta lanes is unchanged
18
+ (`PEN_STACK_LLM_TIMEOUT` default lowered 150 → 90).
19
+ - The General-lane and PEN-RAG cited-answer callers (`pen_stack/rag/ground.py`, `pen_stack/web/llm.py`) now pass
20
+ `kind="general"`.
21
+ - No grounding-guard change; the LLM stays non-load-bearing and the per-lane provenance labels are unchanged.
22
+
6
23
  ## [7.1.1] - 2026-06-24 - PEN-CHAT: General-lane helpfulness fix + benchmark-validity correction
7
24
 
8
25
  ### Fixed
@@ -1,8 +1,8 @@
1
1
  cff-version: 1.2.0
2
2
  message: "If you use PEN-STACK, please cite it as below."
3
3
  title: "PEN-STACK: open infrastructure for genome writing"
4
- version: 7.1.1
5
- date-released: 2026-06-24
4
+ version: 7.1.2
5
+ date-released: 2026-06-25
6
6
  authors:
7
7
  - family-names: "Mahaboob Ali"
8
8
  given-names: "Anees Ahmed"
@@ -1,6 +1,6 @@
1
1
  Metadata-Version: 2.4
2
2
  Name: pen-stack
3
- Version: 7.1.1
3
+ Version: 7.1.2
4
4
  Summary: Open infrastructure for genome writing: the Writable Genome atlas, the Writer Atlas, and the Write Planner.
5
5
  Author-email: Anees Ahmed Mahaboob Ali <ahmedaneesm@gmail.com>
6
6
  License: MIT
@@ -1,2 +1,2 @@
1
1
  """PEN-STACK v3.0 - open infrastructure for genome writing."""
2
- __version__ = "7.1.1"
2
+ __version__ = "7.1.2"
@@ -10,6 +10,7 @@ from __future__ import annotations
10
10
  import json
11
11
  import os
12
12
  import urllib.request
13
+ from functools import lru_cache
13
14
 
14
15
  import numpy as np
15
16
 
@@ -39,6 +40,24 @@ def embed_text(text: str, task: str = "query") -> np.ndarray | None:
39
40
  return None
40
41
 
41
42
 
43
+ # v7.1.2 latency fix: cache live query embeddings in-process. The chat embeds the user's message on every General-lane
44
+ # request; repeat phrasings ("hi", "what is DNA", "what is gene editing") would otherwise hit Ollama every time. The
45
+ # document side is unaffected - corpus embeddings are computed once at build time and committed.
46
+ @lru_cache(maxsize=256)
47
+ def _embed_query_cached(text: str) -> tuple | None:
48
+ v = embed_text(text, task="query")
49
+ return tuple(float(x) for x in v) if v is not None else None
50
+
51
+
52
+ def embed_query(text: str) -> np.ndarray | None:
53
+ """Cached query-side embedding. Identical to `embed_text(text, task='query')` but memoised by text."""
54
+ t = (text or "").strip()
55
+ if not t:
56
+ return embed_text(t, task="query")
57
+ cached = _embed_query_cached(t)
58
+ return np.asarray(cached, dtype="float32") if cached is not None else None
59
+
60
+
42
61
  def embed_corpus(texts: list[str]) -> np.ndarray:
43
62
  """Embed the corpus DOCUMENTS at BUILD time. Raises if the embedder is unreachable (the build must be
44
63
  deterministic and must never silently fall back to a different representation)."""
@@ -90,7 +90,8 @@ def _cited_answer(message: str, r: dict, allow_llm: bool) -> dict:
90
90
  system = ("You answer ONLY from the SOURCES provided. After each claim, cite the bracketed [n] it came from. "
91
91
  "If the sources do not cover the question, say so. Never add a number, name, or vehicle that is "
92
92
  "not in the sources. Never present anything as a PEN-STACK-computed result.")
93
- text, backend = _run_llm(f"SOURCES:\n{ctx}\n\nQUESTION: {message}\n\nAnswer concisely, citing [n].", system)
93
+ text, backend = _run_llm(f"SOURCES:\n{ctx}\n\nQUESTION: {message}\n\nAnswer concisely, citing [n].", system,
94
+ kind="general") # v7.1.2 fast-path: short timeout + token cap for cited answers
94
95
  if text:
95
96
  allow = extract_grounded_numbers({"hits": [h["text"] for h in grounded_hits]})
96
97
  return {**base, "reply": _LABEL + "\n\n" + _enforce_grounding(text.strip(), allow), "backend": backend}
@@ -119,7 +120,7 @@ def ground_general(message: str, *, allow_llm: bool = True) -> dict:
119
120
  from pen_stack.web.llm import SYSTEM_GENERAL, _GENERAL_LABEL, _run_llm
120
121
  text, backend = _run_llm(
121
122
  f"USER: {msg}\n\nAnswer from general knowledge, clearly and at a graduate level. Do not present anything "
122
- f"as a PEN-STACK result.", SYSTEM_GENERAL)
123
+ f"as a PEN-STACK result.", SYSTEM_GENERAL, kind="general") # v7.1.2: fast-path timeout
123
124
  if text:
124
125
  return {"status": "general", "reply": _GENERAL_LABEL + "\n\n" + text.strip(), "sources": [],
125
126
  "provenance": "general", "grounded": False, "backend": backend, "retrieval": r["method"],
@@ -12,7 +12,7 @@ from functools import lru_cache
12
12
  import numpy as np
13
13
 
14
14
  from pen_stack.rag.corpus import emb_path, load_corpus
15
- from pen_stack.rag.embed import embed_text, lexical_scores
15
+ from pen_stack.rag.embed import embed_query, lexical_scores
16
16
 
17
17
 
18
18
  @lru_cache(maxsize=1)
@@ -30,7 +30,7 @@ def _load():
30
30
  def retrieve(query: str, k: int = 4) -> dict:
31
31
  df, emb = _load()
32
32
  texts = df["text"].tolist()
33
- qv = embed_text(query) if emb is not None else None
33
+ qv = embed_query(query) if emb is not None else None # v7.1.2: LRU-cached query embedding
34
34
  if qv is not None and emb is not None:
35
35
  scores = emb @ qv # both L2-normalised -> dot product is cosine
36
36
  method = "semantic (nomic-embed-text)"
@@ -215,10 +215,12 @@ def _angles_footer(message: str) -> str:
215
215
  # -------------------------------------------------------------------------------------- LLM backends
216
216
  # The provider backends live in pen_stack/web/llm_provider.py (PEN-CHAT P-WS2, the swappable abstraction). The chat
217
217
  # narrates through `run_llm`; the grounding guard below makes the GROUNDED result invariant to which provider fired.
218
- def _run_llm(prompt, system, provider=None):
219
- """Delegate to the swappable provider abstraction; returns (text, backend) or (None, None)."""
218
+ def _run_llm(prompt, system, provider=None, kind="default"):
219
+ """Delegate to the swappable provider abstraction; returns (text, backend) or (None, None).
220
+ kind="general" picks the fast-path timeout/token cap (Social / General lane); "default" keeps the longer budget
221
+ for engine-grounded design / explain / meta narration. v7.1.2."""
220
222
  from pen_stack.web.llm_provider import run_llm
221
- return run_llm(prompt, system, provider=provider)
223
+ return run_llm(prompt, system, provider=provider, kind=kind)
222
224
 
223
225
 
224
226
  def _history_block(history):
@@ -316,7 +318,8 @@ def grounded_reply(message: str, history: list | None = None, *, allow_llm: bool
316
318
  # the retriever itself failed: still answer from labelled general knowledge if the LLM is on (never present
317
319
  # it as a PEN-STACK result), else point to the engine.
318
320
  if allow_llm:
319
- text, backend = _run_llm(f"USER: {message}\n\nAnswer from general knowledge, clearly.", SYSTEM_GENERAL)
321
+ text, backend = _run_llm(f"USER: {message}\n\nAnswer from general knowledge, clearly.", SYSTEM_GENERAL,
322
+ kind="general") # v7.1.2 fast-path: short timeout + token cap for the General lane
320
323
  if text:
321
324
  return {"mode": "general", "provenance": "general", "grounded": False, "angles": angles,
322
325
  "tool_results": None, "sources": [],
@@ -24,18 +24,35 @@ def _ollama_base() -> str:
24
24
  return os.getenv("OLLAMA_HOST", "http://localhost:11434").rstrip("/")
25
25
 
26
26
 
27
- def _llm_timeout() -> float:
28
- return float(os.getenv("PEN_STACK_LLM_TIMEOUT", "150"))
27
+ # v7.1.2 latency fix: the General / Social lane never needs the long-form 450-token answer the engine-grounded lanes
28
+ # may need, and it does not benefit from a 150 s hang waiting on a stalled provider. The kind="general" path uses a
29
+ # shorter timeout AND a shorter num_predict; the default path (engine-grounded design / explain / meta) is unchanged.
30
+ def _llm_timeout(kind: str = "default") -> float:
31
+ if kind == "general":
32
+ return float(os.getenv("PEN_STACK_LLM_TIMEOUT_GENERAL", "45"))
33
+ return float(os.getenv("PEN_STACK_LLM_TIMEOUT", "90"))
29
34
 
30
35
 
31
- def _call_ollama(prompt: str, system: str) -> str:
36
+ def _ollama_num_predict(kind: str = "default") -> int:
37
+ if kind == "general":
38
+ return int(os.getenv("OLLAMA_NUM_PREDICT_GENERAL", "280"))
39
+ return int(os.getenv("OLLAMA_NUM_PREDICT", "450"))
40
+
41
+
42
+ def _nemotron_max_tokens(kind: str = "default") -> int:
43
+ if kind == "general":
44
+ return int(os.getenv("NEMOTRON_MAX_TOKENS_GENERAL", "400"))
45
+ return int(os.getenv("NEMOTRON_MAX_TOKENS", "700"))
46
+
47
+
48
+ def _call_ollama(prompt: str, system: str, kind: str = "default") -> str:
32
49
  import requests
33
50
  r = requests.post(
34
51
  f"{_ollama_base()}/api/generate",
35
52
  json={"model": os.getenv("OLLAMA_MODEL", "qwen2.5:3b-instruct"), "prompt": prompt, "system": system,
36
53
  "stream": False, "keep_alive": os.getenv("OLLAMA_KEEP_ALIVE", "30m"),
37
- "options": {"temperature": 0.2, "num_predict": int(os.getenv("OLLAMA_NUM_PREDICT", "450"))}},
38
- timeout=_llm_timeout())
54
+ "options": {"temperature": 0.2, "num_predict": _ollama_num_predict(kind)}},
55
+ timeout=_llm_timeout(kind))
39
56
  r.raise_for_status()
40
57
  return r.json()["response"]
41
58
 
@@ -48,7 +65,7 @@ def _nvidia_key() -> str | None:
48
65
  return f.read_text(encoding="utf-8").strip() if f.exists() else None
49
66
 
50
67
 
51
- def _call_nemotron(prompt: str, system: str) -> str:
68
+ def _call_nemotron(prompt: str, system: str, kind: str = "default") -> str:
52
69
  import requests
53
70
  key = _nvidia_key()
54
71
  if not key:
@@ -58,7 +75,7 @@ def _call_nemotron(prompt: str, system: str) -> str:
58
75
  headers={"Authorization": f"Bearer {key}"},
59
76
  json={"model": os.getenv("NEMOTRON_MODEL", "nvidia/llama-3.3-nemotron-super-49b-v1"),
60
77
  "messages": [{"role": "system", "content": system}, {"role": "user", "content": prompt}],
61
- "temperature": 0.2, "max_tokens": 700}, timeout=_llm_timeout())
78
+ "temperature": 0.2, "max_tokens": _nemotron_max_tokens(kind)}, timeout=_llm_timeout(kind))
62
79
  r.raise_for_status()
63
80
  return r.json()["choices"][0]["message"]["content"]
64
81
 
@@ -82,9 +99,12 @@ def default_provider() -> str:
82
99
  return _order()[0]
83
100
 
84
101
 
85
- def run_llm(prompt: str, system: str, provider: str | None = None) -> tuple[str | None, str | None]:
102
+ def run_llm(prompt: str, system: str, provider: str | None = None,
103
+ kind: str = "default") -> tuple[str | None, str | None]:
86
104
  """Return (text, backend_name) or (None, None). If `provider` is given, use ONLY it (invariance testing);
87
- otherwise try the configured order. The downstream guard makes the GROUNDED result invariant to which fired."""
105
+ otherwise try the configured order. `kind="general"` selects the fast-path timeout / token cap (Social / General
106
+ lane); `kind="default"` (the engine-grounded lanes) keeps the longer budget. The downstream guard makes the
107
+ GROUNDED result invariant to which provider fired."""
88
108
  if os.getenv("PEN_STACK_NO_LLM") == "1":
89
109
  return None, None
90
110
  order = [provider.strip().lower()] if provider else _order()
@@ -93,7 +113,7 @@ def run_llm(prompt: str, system: str, provider: str | None = None) -> tuple[str
93
113
  if fn is None:
94
114
  continue
95
115
  try:
96
- return fn(prompt, system), name
116
+ return fn(prompt, system, kind=kind), name
97
117
  except Exception: # noqa: BLE001 - a dead provider falls through to the next, else the deterministic path
98
118
  continue
99
119
  return None, None
@@ -1,6 +1,6 @@
1
1
  Metadata-Version: 2.4
2
2
  Name: pen-stack
3
- Version: 7.1.1
3
+ Version: 7.1.2
4
4
  Summary: Open infrastructure for genome writing: the Writable Genome atlas, the Writer Atlas, and the Write Planner.
5
5
  Author-email: Anees Ahmed Mahaboob Ali <ahmedaneesm@gmail.com>
6
6
  License: MIT
@@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta"
4
4
 
5
5
  [project]
6
6
  name = "pen-stack"
7
- version = "7.1.1"
7
+ version = "7.1.2"
8
8
  description = "Open infrastructure for genome writing: the Writable Genome atlas, the Writer Atlas, and the Write Planner."
9
9
  readme = "README.md"
10
10
  requires-python = ">=3.11"
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