pen-stack 5.13.0__tar.gz → 6.0.0__tar.gz
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- {pen_stack-5.13.0 → pen_stack-6.0.0}/CHANGELOG.md +20 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/CITATION.cff +1 -1
- {pen_stack-5.13.0 → pen_stack-6.0.0}/PKG-INFO +18 -4
- {pen_stack-5.13.0 → pen_stack-6.0.0}/README.md +16 -2
- pen_stack-6.0.0/docs/STABILITY.md +51 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/__init__.py +1 -1
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack.egg-info/PKG-INFO +18 -4
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack.egg-info/SOURCES.txt +1 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pyproject.toml +2 -2
- {pen_stack-5.13.0 → pen_stack-6.0.0}/LICENSE +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/MANIFEST.in +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/bench/run.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_bench/LEADERBOARD.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_bench/README.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_bench/SHA256SUMS +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_bench/SUBMISSIONS.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_bench/tasks.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_challenge/README.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/benchmarks/genome_writing_challenge/SUBMISSIONS.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/antipeg.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/atlas_families.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/bridge_offtarget_profile.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/capsid_epitope_oracle.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/capsid_sequences.fasta +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/cargo_polish.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/cell_types.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/datasets.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/delivery_constraints.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/delivery_rules.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/delivery_vehicles.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/gates_v3.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/genotoxicity_oracle.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/gsh_validated_heldout.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/intent_weights.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/known_unknowns.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/llm.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/monitor_queries.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/oracles/scope_cards.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/rules/delivery.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/rules/fold.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/rules/multiplex.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/rules/payload.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/rules/reachability.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/safety/hazard_registry.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/safety/policy.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/safety/probes.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/score_axes.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/seroprevalence.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/target_sites.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/universe_crosswalk.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/write_types.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/configs/wtkb_curated.yaml +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/data/curated/bridge_offtarget_energetics.json +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/data/curated/bridge_offtarget_profile_measured.parquet +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/data/curated/gene_coords.parquet +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/data/curated/unified_editor_universe.parquet +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/BACKLOG.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/DEPLOY.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/INFRA.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/MCP.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/RELEASING.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/REPRO.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/agent.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/alphagenome_feasibility.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/autonomy.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/benchmark_circularity.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/biosecurity.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/build_interface.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/cards/atlas.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/cards/durability.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/cards/safety.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/challenge.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/closed_loop.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/co_scientist.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/co_scientist_loop.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/delivery.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/delivery_immunology.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/digital_twin.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/dissemination.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/environment.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/experiment_design.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/generative_design.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/index.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/integrations.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/mechanistic_constraints.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/oracles.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/positioning.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/private_data_formats.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/quickstart.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/responsible_use.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/rules.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/scope.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/scorecard.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/tutorials/compare-families.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/tutorials/score-deliverability.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/tutorials/where-can-i-write.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/tutorials/which-writer-reaches-locus.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/uncertainty.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/verify.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/world_model.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/writer_verification.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/docs/wtkb.md +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/_resources.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/active/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/active/acquire.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/active/design.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/active/validate.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/adapt/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/adapt/finetune.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/adapt/ingest.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/adapt/pipeline.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/adapt/recalibrate.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/adapt/report.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/cite.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/co_scientist.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/epistemic.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/guardrails.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/mcp_server.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/orchestrator.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/orchestrator_live.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/pen_agent.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/scope.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/agent/tools.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/build_wtkb.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/crosslink.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/expand.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/schema.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/scorecard.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/universe.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/variant_propose.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/atlas/writer_verify.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/activity.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/cli.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/fold_qc.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/guide_qc.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/ingest.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/offtarget.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/offtarget_energetics.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/ortholog_screen.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/bridge/pipeline.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/build/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/build/ingest.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/build/protocol.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/build/simlab.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/cli.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/encode.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/genome.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/ingest_chromatin.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/ingest_integration.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/ingest_safety_annot.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/data/ingest_trip.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/design/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/design/generate.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/design/pareto.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/design/space.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/env/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/env/genome_writing_env.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/env/policies.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/graph/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/graph/build.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/graph/cell_types.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/graph/ingest.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/graph/query.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/graph/schema.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/loop/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/loop/continual.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/loop/cycle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/loop/drift.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/mech/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/mech/classify_atlas.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/mech/whitelist.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/monitor/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/monitor/europepmc.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/monitor/run.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/monitor/triage.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/cache.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/energetics.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/genome.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/protein_design.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/rna.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/schema.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/structure.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/oracles/vcell.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/antipeg_oracle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/capsid_epitope_oracle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/cargo.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/cargo_polish.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/delivery.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/delivery_constraints.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/delivery_immunology.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/delivery_vehicles.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/genotoxicity_oracle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/immune_profile.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/innate_sensing.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/multiplex.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/optimize.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/pipeline.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/report.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/router.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/seroprevalence_oracle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/planner/target_site.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rag/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rag/index.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rag/llm.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rag/qa.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rules/__init__.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rules/evaluators.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rules/loader.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/pen_stack/rules/schema.py +0 -0
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- {pen_stack-5.13.0 → pen_stack-6.0.0}/scripts/p3_benchmark_report.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/scripts/p4_genome_scan.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/scripts/p52_build_genotox_oracle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/scripts/p53_build_epitope_oracle.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/scripts/ws_b_report.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/scripts/ws_c_report.py +0 -0
- {pen_stack-5.13.0 → pen_stack-6.0.0}/setup.cfg +0 -0
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All notable changes to PEN-STACK are documented here. This file follows
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[Keep a Changelog](https://keepachangelog.com/) and the program's phase structure.
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## [6.0.0] - 2026-06-11 - 1.0 — First Stable (the graduation)
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**The Closed-Loop arc is complete (7/7), and PEN-STACK graduates to "1.0 — First Stable."** The public API
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exercised across every surface — verify, safety, generative design, twin, experiment design, build interface,
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closed loop, co-scientist, and the Genome-Writing Challenge — is documented and **frozen** with a deprecation
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policy. "First Stable" is **earned, not declared**: it is cut only after the closed loop is demonstrated (v5.12),
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the benchmark is public (v5.13), and the integration surface ships.
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### Changed
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- **`Development Status :: 5 - Production/Stable`** (was Beta). Version **6.0.0** (MAJOR).
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- The public API is documented + frozen with a deprecation policy: **`docs/STABILITY.md`** (semver from 6.0.0;
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deprecations warn ≥1 MINOR before removal in a MAJOR; the `OracleResult`/`Verdict`/`SafetyVerdict`/immune-profile
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contracts and invariants — incl. `collapsed_score is None` and the no-fabrication guard — are stable across 6.x).
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- The Genome-Writing Challenge is **public**.
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### Notes
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- "1.0 — First Stable" is a commitment to **API stability**, **not** a claim of solving genetic engineering. The
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unknown funnel remains — made legible (scope flags, known-unknowns, honest baselines, no fabrication), not
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hidden. The high version numbers of the program's fast youth finally meet a real stability commitment.
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## [5.13.0] - 2026-06-11 - v5.13 release: The Standard (Genome-Writing Challenge + Co-Scientist II)
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Name: pen-stack
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Version:
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Version: 6.0.0
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Summary: Open infrastructure for genome writing: the Writable Genome atlas, the Writer Atlas, and the Write Planner.
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Author-email: Anees Ahmed Mahaboob Ali <ahmedaneesm@gmail.com>
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License: MIT
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Project-URL: Benchmark, https://github.com/ahmedanees-m/pen-stack/tree/main/benchmarks/genome_writing_bench
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## 🎓 v6.0.0 — "1.0 — First Stable"
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The **Closed-Loop arc is complete (7/7)** and PEN-STACK has graduated to **1.0 — First Stable**. The public API
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exercised across every surface — `verify`, `safety`, generative `design`, the `twin`, `active` experiment design,
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the `build` interface, the closed `loop`, the `co_scientist`, and the **Genome-Writing Challenge** — is documented
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and **frozen** with a deprecation policy ([`docs/STABILITY.md`](docs/STABILITY.md)). `Development Status ::
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5 - Production/Stable`. "First Stable" is **earned, not declared** — cut only after the closed loop was
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demonstrated (v5.12) and the benchmark went public (v5.13).
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> "1.0 — First Stable" is a commitment to **API stability**, not a claim of solving genetic engineering. The
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> hidden.
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## What is new in v5.13 — The Standard (Genome-Writing Challenge + Co-Scientist II)
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v5.13 (**Closed-Loop arc, Cycle 7 of 7**) makes PEN-STACK the field's reference and its most useful face: the
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[](https://codecov.io/gh/ahmedanees-m/pen-stack)
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[](LICENSE)
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[](https://www.python.org/)
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[](CHANGELOG.md)
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[](docs/STABILITY.md)
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[](tests/)
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a pre-registered, honest baseline before release.
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## 🎓 v6.0.0 — "1.0 — First Stable"
|
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The **Closed-Loop arc is complete (7/7)** and PEN-STACK has graduated to **1.0 — First Stable**. The public API
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exercised across every surface — `verify`, `safety`, generative `design`, the `twin`, `active` experiment design,
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the `build` interface, the closed `loop`, the `co_scientist`, and the **Genome-Writing Challenge** — is documented
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and **frozen** with a deprecation policy ([`docs/STABILITY.md`](docs/STABILITY.md)). `Development Status ::
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5 - Production/Stable`. "First Stable" is **earned, not declared** — cut only after the closed loop was
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demonstrated (v5.12) and the benchmark went public (v5.13).
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> "1.0 — First Stable" is a commitment to **API stability**, not a claim of solving genetic engineering. The
|
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> unknown funnel remains — made legible (scope flags, known-unknowns, honest baselines, no fabrication), not
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> hidden.
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## What is new in v5.13 — The Standard (Genome-Writing Challenge + Co-Scientist II)
|
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v5.13 (**Closed-Loop arc, Cycle 7 of 7**) makes PEN-STACK the field's reference and its most useful face: the
|
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# API stability & deprecation policy (v6.0.0 — "1.0 — First Stable")
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At **v6.0.0**, PEN-STACK graduates to **1.0 — First Stable**: the public API exercised across all surfaces is
|
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documented and frozen, with a deprecation policy. "First Stable" is **earned, not declared** — it is cut only
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after the closed loop is demonstrated (v5.12), the benchmark is public (v5.13), and the integration surface ships.
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+
> "1.0 — First Stable" is a commitment to **API stability**, not a claim of solving genetic engineering. The
|
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> unknown funnel remains — made legible (scope flags, known-unknowns, honest baselines), not hidden.
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## Versioning
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PEN-STACK follows **semantic versioning** from 6.0.0:
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- **MAJOR** (`x.0.0`) — backward-incompatible changes to the public API (below).
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- **MINOR** (`6.x.0`) — backward-compatible additions.
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- **PATCH** (`6.0.x`) — backward-compatible fixes.
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## The public API (frozen at 1.0)
|
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These are the supported entry points. Their **signatures and return-shape keys** are stable across 6.x:
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| Surface | Entry point |
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+
|---|---|
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| Verify a write | `pen_stack.verify.verify(design, question=None, *, actor=…) -> Verdict` (legal · safety · immune_profile · confidence · scope) |
|
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25
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+
| Safety gate | `pen_stack.safety.safety_gate(design, *, actor=…) -> SafetyVerdict` |
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+
| Generative design | `pen_stack.design.generate_designs(...)`, `pen_stack.design.pareto_front(...)` |
|
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| Digital twin | `pen_stack.twin.predict_outcome(design, cell_state)`, `pen_stack.twin.calibrate_outcome(...)` |
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| Experiment design | `pen_stack.active.select_batch(...)`, `pen_stack.active.expected_information_gain(...)` |
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| Build interface | `pen_stack.build.export_protocol(...)`, `pen_stack.build.ingest_result(...)`, `pen_stack.build.run_simulated(...)` |
|
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+
| Closed loop | `pen_stack.loop.run_loop(goal, cell_state, …)` |
|
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| Co-scientist | `pen_stack.agent.co_scientist.co_scientist_session(goal, cell_state)` |
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| Challenge | `benchmarks.genome_writing_challenge.harness.evaluate(submission, round_id)` |
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| CLI / MCP | `pen-stack` / `pen-bridge` console scripts; `pen_stack.agent.mcp_server` |
|
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Internal helpers (underscore-prefixed names, modules under `pen_stack/*/_*`, the `data/`/`wgenome/` training
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+
pipelines) are **not** part of the public API and may change in any release.
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## Deprecation policy
|
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|
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40
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+
- A public API element is deprecated by a **`DeprecationWarning`** and a CHANGELOG note **at least one MINOR
|
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release** before removal.
|
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+
- Removal happens only in a **MAJOR** release.
|
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- The `OracleResult` / `Verdict` / `SafetyVerdict` / immune-profile **contracts** (field names + invariants such as
|
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+
`collapsed_score is None` and the no-fabrication guard) are stable across 6.x.
|
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+
|
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+
## What stability does NOT promise
|
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|
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|
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|
+
- Model **numbers** may change as oracles / data are updated (they are version-pinned + provenanced; results are
|
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reproducible *given a pinned version*, not constant forever).
|
|
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|
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- **Scope** stays honest: out-of-scope questions are deferred, known-unknowns declared, baselines reported — at
|
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+
1.0 and beyond.
|
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@@ -1,2 +1,2 @@
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1
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"""PEN-STACK v3.0 - open infrastructure for genome writing."""
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__version__ = "
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__version__ = "6.0.0"
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@@ -1,6 +1,6 @@
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Metadata-Version: 2.4
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Name: pen-stack
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Version:
|
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Version: 6.0.0
|
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Summary: Open infrastructure for genome writing: the Writable Genome atlas, the Writer Atlas, and the Write Planner.
|
|
5
5
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Author-email: Anees Ahmed Mahaboob Ali <ahmedaneesm@gmail.com>
|
|
6
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License: MIT
|
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Project-URL: Issues, https://github.com/ahmedanees-m/pen-stack/issues
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Project-URL: Benchmark, https://github.com/ahmedanees-m/pen-stack/tree/main/benchmarks/genome_writing_bench
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Keywords: genome-writing,genome-editing,bridge-recombinase,safe-harbor,writable-genome,writer-atlas,write-planner,bioinformatics
|
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Everything is built on bulk-downloadable public data, runs on a single GPU, and is validated **blind** against
|
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## 🎓 v6.0.0 — "1.0 — First Stable"
|
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|
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+
The **Closed-Loop arc is complete (7/7)** and PEN-STACK has graduated to **1.0 — First Stable**. The public API
|
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141
|
+
exercised across every surface — `verify`, `safety`, generative `design`, the `twin`, `active` experiment design,
|
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|
+
the `build` interface, the closed `loop`, the `co_scientist`, and the **Genome-Writing Challenge** — is documented
|
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+
and **frozen** with a deprecation policy ([`docs/STABILITY.md`](docs/STABILITY.md)). `Development Status ::
|
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5 - Production/Stable`. "First Stable" is **earned, not declared** — cut only after the closed loop was
|
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+
demonstrated (v5.12) and the benchmark went public (v5.13).
|
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|
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> "1.0 — First Stable" is a commitment to **API stability**, not a claim of solving genetic engineering. The
|
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> unknown funnel remains — made legible (scope flags, known-unknowns, honest baselines, no fabrication), not
|
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> hidden.
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## What is new in v5.13 — The Standard (Genome-Writing Challenge + Co-Scientist II)
|
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138
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139
153
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v5.13 (**Closed-Loop arc, Cycle 7 of 7**) makes PEN-STACK the field's reference and its most useful face: the
|
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description = "Open infrastructure for genome writing: the Writable Genome atlas, the Writer Atlas, and the Write Planner."
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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File without changes
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