newlife 0.1.0__tar.gz
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- newlife-0.1.0/.gitignore +8 -0
- newlife-0.1.0/LICENSE +202 -0
- newlife-0.1.0/PKG-INFO +96 -0
- newlife-0.1.0/README.md +73 -0
- newlife-0.1.0/pyproject.toml +48 -0
- newlife-0.1.0/src/newlife/__init__.py +11 -0
- newlife-0.1.0/src/newlife/adapters/__init__.py +1 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/__init__.py +1 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/bare_control.py +144 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/cases.py +1129 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/derive.py +195 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/discovery.py +58 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/foreign.py +222 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/lowering.py +203 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/public_api_audit.py +123 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/staging.py +381 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/world_runtime.py +144 -0
- newlife-0.1.0/src/newlife/adapters/process_bigraph/wrapper.py +381 -0
- newlife-0.1.0/src/newlife/adapters/reference_kernel/__init__.py +1 -0
- newlife-0.1.0/src/newlife/adapters/reference_kernel/cases.py +709 -0
- newlife-0.1.0/src/newlife/adapters/reference_kernel/kernel.py +393 -0
- newlife-0.1.0/src/newlife/adapters/reference_kernel/lowering.py +169 -0
- newlife-0.1.0/src/newlife/adapters/reference_kernel/world_runtime.py +31 -0
- newlife-0.1.0/src/newlife/cli.py +170 -0
- newlife-0.1.0/src/newlife/conform/__init__.py +1 -0
- newlife-0.1.0/src/newlife/conform/contract/__init__.py +1 -0
- newlife-0.1.0/src/newlife/conform/contract/canonical_ruler.py +42 -0
- newlife-0.1.0/src/newlife/conform/cross_runtime_verdict.py +186 -0
- newlife-0.1.0/src/newlife/conform/dep_declaration.py +166 -0
- newlife-0.1.0/src/newlife/conform/derive_authority_verdict.py +266 -0
- newlife-0.1.0/src/newlife/conform/eighth_world_verdict.py +136 -0
- newlife-0.1.0/src/newlife/conform/external_package_verdict.py +198 -0
- newlife-0.1.0/src/newlife/conform/fifth_world_verdict.py +80 -0
- newlife-0.1.0/src/newlife/conform/fixtures/expected/continuous_next_event.json +92 -0
- newlife-0.1.0/src/newlife/conform/fixtures/expected/coupled_mechanics_division.json +121 -0
- newlife-0.1.0/src/newlife/conform/fixtures/expected/effect_algebra_transfer.json +44 -0
- newlife-0.1.0/src/newlife/conform/fixtures/expected/execution_budget.json +127 -0
- newlife-0.1.0/src/newlife/conform/fixtures/expected/hook_authority.json +95 -0
- newlife-0.1.0/src/newlife/conform/fixtures.py +56 -0
- newlife-0.1.0/src/newlife/conform/foreign_process_verdict.py +188 -0
- newlife-0.1.0/src/newlife/conform/fourth_world_verdict.py +214 -0
- newlife-0.1.0/src/newlife/conform/host/__init__.py +1 -0
- newlife-0.1.0/src/newlife/conform/judgment.py +155 -0
- newlife-0.1.0/src/newlife/conform/manifest.py +118 -0
- newlife-0.1.0/src/newlife/conform/ninth_world_verdict.py +103 -0
- newlife-0.1.0/src/newlife/conform/probes.py +186 -0
- newlife-0.1.0/src/newlife/conform/second_world_verdict.py +325 -0
- newlife-0.1.0/src/newlife/conform/seventh_world_verdict.py +137 -0
- newlife-0.1.0/src/newlife/conform/sixth_world_verdict.py +145 -0
- newlife-0.1.0/src/newlife/conform/solver_backed_verdict.py +201 -0
- newlife-0.1.0/src/newlife/conform/tenth_verdict.py +140 -0
- newlife-0.1.0/src/newlife/conform/third_world_verdict.py +183 -0
- newlife-0.1.0/src/newlife/conform/verdict.py +444 -0
- newlife-0.1.0/src/newlife/conform/verdict_rot.py +315 -0
- newlife-0.1.0/src/newlife/conform/yield_verdict.py +221 -0
- newlife-0.1.0/src/newlife/core/__init__.py +1 -0
- newlife-0.1.0/src/newlife/core/compare.py +167 -0
- newlife-0.1.0/src/newlife/core/contracts.py +224 -0
- newlife-0.1.0/src/newlife/core/errors.py +73 -0
- newlife-0.1.0/src/newlife/core/harness.py +253 -0
- newlife-0.1.0/src/newlife/core/lowering_contract.py +99 -0
- newlife-0.1.0/src/newlife/core/runtime.py +47 -0
- newlife-0.1.0/src/newlife/core/verdict_seam.py +90 -0
- newlife-0.1.0/src/newlife/gates/__init__.py +5 -0
- newlife-0.1.0/src/newlife/gates/silent_degradation_scan.py +499 -0
- newlife-0.1.0/src/newlife/gates/unit_alignment.py +207 -0
- newlife-0.1.0/src/newlife/gates/vacuous_criterion_scan.py +161 -0
- newlife-0.1.0/src/newlife/mechanisms/__init__.py +1 -0
- newlife-0.1.0/src/newlife/mechanisms/foreign_dfba/__init__.py +0 -0
- newlife-0.1.0/src/newlife/mechanisms/foreign_dfba/declaration.py +66 -0
- newlife-0.1.0/src/newlife/mechanisms/foreign_growth/__init__.py +0 -0
- newlife-0.1.0/src/newlife/mechanisms/foreign_growth/declaration.py +48 -0
- newlife-0.1.0/src/newlife/mechanisms/foreign_monod/__init__.py +0 -0
- newlife-0.1.0/src/newlife/mechanisms/foreign_monod/declaration.py +61 -0
- newlife-0.1.0/src/newlife/mechanisms/fourth_world/__init__.py +0 -0
- newlife-0.1.0/src/newlife/mechanisms/fourth_world/genealogy.py +103 -0
- newlife-0.1.0/src/newlife/mechanisms/fourth_world/spec.py +62 -0
- newlife-0.1.0/src/newlife/mechanisms/fourth_world/world.py +68 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/__init__.py +1 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/__main__.py +34 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/assay.py +169 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/calibration.py +171 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/injection.py +201 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/mechanisms.py +721 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/model.py +256 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/spec.py +49 -0
- newlife-0.1.0/src/newlife/mechanisms/resource_foraging/world.py +689 -0
- newlife-0.1.0/src/newlife/mechanisms/second_world/__init__.py +2 -0
- newlife-0.1.0/src/newlife/mechanisms/second_world/mechanisms.py +120 -0
- newlife-0.1.0/src/newlife/mechanisms/second_world/ms_binary.py +101 -0
- newlife-0.1.0/src/newlife/mechanisms/second_world/ms_coalescent.py +250 -0
- newlife-0.1.0/src/newlife/mechanisms/second_world/rng_mapping.py +36 -0
- newlife-0.1.0/src/newlife/mechanisms/second_world/world.py +107 -0
- newlife-0.1.0/src/newlife/mechanisms/third_world/__init__.py +0 -0
- newlife-0.1.0/src/newlife/mechanisms/third_world/moran.py +100 -0
- newlife-0.1.0/src/newlife/provenance.py +119 -0
- newlife-0.1.0/src/newlife/scaffold/__init__.py +145 -0
- newlife-0.1.0/src/newlife/scaffold/prereg.sh +362 -0
- newlife-0.1.0/src/newlife/scaffold/templates/gitignore +4 -0
- newlife-0.1.0/src/newlife/scaffold/templates/prereg.md +59 -0
- newlife-0.1.0/src/newlife/scaffold/templates/verdict.py.template +134 -0
- newlife-0.1.0/src/newlife/skills/decidable-question/SKILL.md +263 -0
- newlife-0.1.0/src/newlife/skills/preregister-verdict/SKILL.md +146 -0
- newlife-0.1.0/tests/core/test_compare.py +259 -0
- newlife-0.1.0/tests/fourth_world/test_reuse.py +161 -0
- newlife-0.1.0/tests/resource_foraging/test_calibration.py +70 -0
- newlife-0.1.0/tests/resource_foraging/test_world.py +262 -0
- newlife-0.1.0/tests/second_world/conftest.py +40 -0
- newlife-0.1.0/tests/second_world/test_mechanism_registry.py +63 -0
- newlife-0.1.0/tests/second_world/test_ms_grid.py +63 -0
- newlife-0.1.0/tests/second_world/test_rng_mapping.py +58 -0
- newlife-0.1.0/tests/second_world/test_second_world_verdict.py +70 -0
- newlife-0.1.0/tests/test_bypass_negatives.py +162 -0
- newlife-0.1.0/tests/test_cli_skills_blocks.py +74 -0
- newlife-0.1.0/tests/test_contracts.py +144 -0
- newlife-0.1.0/tests/test_foreign_process.py +42 -0
- newlife-0.1.0/tests/test_gates.py +55 -0
- newlife-0.1.0/tests/test_lowering_contract.py +121 -0
- newlife-0.1.0/tests/test_lowering_controls.py +119 -0
- newlife-0.1.0/tests/test_ms_vendor.py +32 -0
- newlife-0.1.0/tests/test_pb_lowering_dispatch.py +154 -0
- newlife-0.1.0/tests/test_public_english.py +65 -0
- newlife-0.1.0/tests/test_reference_cases.py +153 -0
- newlife-0.1.0/tests/test_ruler.py +102 -0
- newlife-0.1.0/tests/test_safety_line_dedup.py +55 -0
- newlife-0.1.0/tests/test_scaffold.py +183 -0
- newlife-0.1.0/tests/test_staging_cases.py +151 -0
- newlife-0.1.0/tests/test_staging_derivation.py +178 -0
- newlife-0.1.0/tests/test_staging_validation.py +113 -0
- newlife-0.1.0/tests/test_verdict.py +69 -0
- newlife-0.1.0/tests/test_vivarium_cases.py +53 -0
- newlife-0.1.0/tests/test_vivarium_profile.py +210 -0
- newlife-0.1.0/tests/third_world/test_oracle_conformance.py +254 -0
newlife-0.1.0/.gitignore
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newlife-0.1.0/LICENSE
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limitations under the License.
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newlife-0.1.0/PKG-INFO
ADDED
|
@@ -0,0 +1,96 @@
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1
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Metadata-Version: 2.5
|
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2
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Name: newlife
|
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+
Version: 0.1.0
|
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4
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Summary: Preregistration harness for simulation: freeze what would count as an answer in git, compute the verdict mechanically, and prove from commit ancestry that the outputs post-date the freeze.
|
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+
Project-URL: Homepage, https://github.com/hzshen88/newlife
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Project-URL: Repository, https://github.com/hzshen88/newlife
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Author: hzshen88
|
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License-Expression: Apache-2.0
|
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License-File: LICENSE
|
|
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+
Keywords: preregistration,provenance,reproducibility,scientific-workflow,simulation,systems-biology
|
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+
Classifier: Development Status :: 3 - Alpha
|
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|
+
Classifier: Intended Audience :: Science/Research
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Classifier: Natural Language :: English
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Classifier: Programming Language :: Python :: 3.12
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Classifier: Topic :: Scientific/Engineering :: Bio-Informatics
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Requires-Python: >=3.12
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Requires-Dist: proofroot<0.2,>=0.1
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Provides-Extra: process-bigraph
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Requires-Dist: process-bigraph==1.8.3; extra == 'process-bigraph'
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Provides-Extra: spatio-flux
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Requires-Dist: spatio-flux==1.4.0; extra == 'spatio-flux'
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Description-Content-Type: text/markdown
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# newlife
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+
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**A preregistration harness for simulation.** Freeze what would count as an answer
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+
*before* you run anything; let the machine — not your judgement after the fact —
|
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28
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+
decide whether the criteria were met.
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+
|
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+
## Install
|
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+
|
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32
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+
Requires Python 3.12 or newer and `git`.
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33
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+
|
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34
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+
```bash
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35
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+
python -m pip install newlife
|
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|
+
# Optional simulation backends:
|
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37
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+
python -m pip install "newlife[process-bigraph]"
|
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38
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+
python -m pip install "newlife[spatio-flux]"
|
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39
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+
```
|
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40
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+
|
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Start in your own repository:
|
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+
|
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+
```bash
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+
mkdir my-research && cd my-research
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+
git init
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46
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+
git config user.name "Your Name"
|
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47
|
+
git config user.email "you@example.com"
|
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+
newlife init 2026-09-05-my-question # scaffold a question folder; commits it,
|
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49
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+
# deliberately leaving prereg.md uncommitted
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50
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+
$EDITOR questions/2026-09-05-my-question/prereg.md
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+
newlife freeze questions/2026-09-05-my-question
|
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+
$EDITOR questions/2026-09-05-my-question/verdict.py
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+
newlife run questions/2026-09-05-my-question
|
|
54
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+
newlife check questions/2026-09-05-my-question
|
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55
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+
git add questions/2026-09-05-my-question/results
|
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+
git commit -m "record verdict"
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+
newlife audit questions/2026-09-05-my-question
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+
```
|
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59
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+
|
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60
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+
`audit` proves, from commit ancestry rather than forgeable dates: the registration has a
|
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61
|
+
freeze commit, the stamped hash matches it, the content was never edited afterwards, and
|
|
62
|
+
**every committed output post-dates the freeze**. Questions are siblings, not a chain:
|
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63
|
+
a question's verdict never runs another question's runner.
|
|
64
|
+
|
|
65
|
+
## What the contract layer does
|
|
66
|
+
|
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67
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+
`BiologicalProfile` enforces four contracts — `StateClaim`, `MechanismSpec`, `Effect`,
|
|
68
|
+
`Resolver`. A mechanism declares which paths it owns and which effects it may emit;
|
|
69
|
+
writing anywhere else raises `newlife.core.errors.CommitAuthorityError` **from the
|
|
70
|
+
contract layer, not from your solver**. That distinction is load-bearing: "an exception
|
|
71
|
+
was raised" is not the same as "the contract stopped it", and a negative control that
|
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72
|
+
conflates them proves nothing.
|
|
73
|
+
|
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74
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+
Third-party simulation processes are admitted unmodified. Verified against
|
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75
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+
`process-bigraph`'s own processes, `spatio-flux` (Monod kinetics, dynamic FBA behind a
|
|
76
|
+
GLPK solver), and a hand-wrapped `tellurium` ODE model — trajectories byte-identical to
|
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77
|
+
running the same code without newlife.
|
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78
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+
|
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79
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+
## Gates that ship with it
|
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80
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+
|
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81
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+
`newlife check` runs three checks against your files: criteria that are **true by
|
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82
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+
construction** (a comprehension iterating a named constant while discarding the loop
|
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83
|
+
variable is a repetition, not a sweep); parse failures that **silently fall back to a
|
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84
|
+
convenient default**; and whether the units your registration declares are exactly the
|
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85
|
+
units your runner computes. Each of the three was written after that exact defect shipped
|
|
86
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+
undetected — the third one caught a real misalignment the first time it ran.
|
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87
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+
|
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88
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+
Also included: `newlife skills install` puts two AI skills (shaping a question into a
|
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89
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+
decidable one; writing a registration that will not veto itself) where your assistant
|
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90
|
+
reads them.
|
|
91
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+
|
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92
|
+
`proofroot` is installed transitively and supplies RNG stream derivation, canonical
|
|
93
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+
serialization, and the evidence-tier vocabulary.
|
|
94
|
+
|
|
95
|
+
Source, design rationale, and the record of every milestone judged so far:
|
|
96
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+
<https://github.com/hzshen88/newlife>
|
newlife-0.1.0/README.md
ADDED
|
@@ -0,0 +1,73 @@
|
|
|
1
|
+
# newlife
|
|
2
|
+
|
|
3
|
+
**A preregistration harness for simulation.** Freeze what would count as an answer
|
|
4
|
+
*before* you run anything; let the machine — not your judgement after the fact —
|
|
5
|
+
decide whether the criteria were met.
|
|
6
|
+
|
|
7
|
+
## Install
|
|
8
|
+
|
|
9
|
+
Requires Python 3.12 or newer and `git`.
|
|
10
|
+
|
|
11
|
+
```bash
|
|
12
|
+
python -m pip install newlife
|
|
13
|
+
# Optional simulation backends:
|
|
14
|
+
python -m pip install "newlife[process-bigraph]"
|
|
15
|
+
python -m pip install "newlife[spatio-flux]"
|
|
16
|
+
```
|
|
17
|
+
|
|
18
|
+
Start in your own repository:
|
|
19
|
+
|
|
20
|
+
```bash
|
|
21
|
+
mkdir my-research && cd my-research
|
|
22
|
+
git init
|
|
23
|
+
git config user.name "Your Name"
|
|
24
|
+
git config user.email "you@example.com"
|
|
25
|
+
newlife init 2026-09-05-my-question # scaffold a question folder; commits it,
|
|
26
|
+
# deliberately leaving prereg.md uncommitted
|
|
27
|
+
$EDITOR questions/2026-09-05-my-question/prereg.md
|
|
28
|
+
newlife freeze questions/2026-09-05-my-question
|
|
29
|
+
$EDITOR questions/2026-09-05-my-question/verdict.py
|
|
30
|
+
newlife run questions/2026-09-05-my-question
|
|
31
|
+
newlife check questions/2026-09-05-my-question
|
|
32
|
+
git add questions/2026-09-05-my-question/results
|
|
33
|
+
git commit -m "record verdict"
|
|
34
|
+
newlife audit questions/2026-09-05-my-question
|
|
35
|
+
```
|
|
36
|
+
|
|
37
|
+
`audit` proves, from commit ancestry rather than forgeable dates: the registration has a
|
|
38
|
+
freeze commit, the stamped hash matches it, the content was never edited afterwards, and
|
|
39
|
+
**every committed output post-dates the freeze**. Questions are siblings, not a chain:
|
|
40
|
+
a question's verdict never runs another question's runner.
|
|
41
|
+
|
|
42
|
+
## What the contract layer does
|
|
43
|
+
|
|
44
|
+
`BiologicalProfile` enforces four contracts — `StateClaim`, `MechanismSpec`, `Effect`,
|
|
45
|
+
`Resolver`. A mechanism declares which paths it owns and which effects it may emit;
|
|
46
|
+
writing anywhere else raises `newlife.core.errors.CommitAuthorityError` **from the
|
|
47
|
+
contract layer, not from your solver**. That distinction is load-bearing: "an exception
|
|
48
|
+
was raised" is not the same as "the contract stopped it", and a negative control that
|
|
49
|
+
conflates them proves nothing.
|
|
50
|
+
|
|
51
|
+
Third-party simulation processes are admitted unmodified. Verified against
|
|
52
|
+
`process-bigraph`'s own processes, `spatio-flux` (Monod kinetics, dynamic FBA behind a
|
|
53
|
+
GLPK solver), and a hand-wrapped `tellurium` ODE model — trajectories byte-identical to
|
|
54
|
+
running the same code without newlife.
|
|
55
|
+
|
|
56
|
+
## Gates that ship with it
|
|
57
|
+
|
|
58
|
+
`newlife check` runs three checks against your files: criteria that are **true by
|
|
59
|
+
construction** (a comprehension iterating a named constant while discarding the loop
|
|
60
|
+
variable is a repetition, not a sweep); parse failures that **silently fall back to a
|
|
61
|
+
convenient default**; and whether the units your registration declares are exactly the
|
|
62
|
+
units your runner computes. Each of the three was written after that exact defect shipped
|
|
63
|
+
undetected — the third one caught a real misalignment the first time it ran.
|
|
64
|
+
|
|
65
|
+
Also included: `newlife skills install` puts two AI skills (shaping a question into a
|
|
66
|
+
decidable one; writing a registration that will not veto itself) where your assistant
|
|
67
|
+
reads them.
|
|
68
|
+
|
|
69
|
+
`proofroot` is installed transitively and supplies RNG stream derivation, canonical
|
|
70
|
+
serialization, and the evidence-tier vocabulary.
|
|
71
|
+
|
|
72
|
+
Source, design rationale, and the record of every milestone judged so far:
|
|
73
|
+
<https://github.com/hzshen88/newlife>
|
|
@@ -0,0 +1,48 @@
|
|
|
1
|
+
[project]
|
|
2
|
+
name = "newlife"
|
|
3
|
+
version = "0.1.0"
|
|
4
|
+
description = "Preregistration harness for simulation: freeze what would count as an answer in git, compute the verdict mechanically, and prove from commit ancestry that the outputs post-date the freeze."
|
|
5
|
+
readme = "README.md"
|
|
6
|
+
requires-python = ">=3.12"
|
|
7
|
+
license = "Apache-2.0"
|
|
8
|
+
license-files = ["LICENSE"]
|
|
9
|
+
authors = [{ name = "hzshen88" }]
|
|
10
|
+
keywords = ["preregistration", "reproducibility", "simulation", "provenance",
|
|
11
|
+
"systems-biology", "scientific-workflow"]
|
|
12
|
+
classifiers = [
|
|
13
|
+
"Development Status :: 3 - Alpha",
|
|
14
|
+
"Intended Audience :: Science/Research",
|
|
15
|
+
"Natural Language :: English",
|
|
16
|
+
"Programming Language :: Python :: 3.12",
|
|
17
|
+
"Topic :: Scientific/Engineering :: Bio-Informatics",
|
|
18
|
+
]
|
|
19
|
+
dependencies = ["proofroot>=0.1,<0.2"]
|
|
20
|
+
|
|
21
|
+
[project.optional-dependencies]
|
|
22
|
+
process-bigraph = ["process-bigraph==1.8.3"]
|
|
23
|
+
# 第十六个里程碑:一个真正独立的第三方包。走 optional extra,不进主依赖面
|
|
24
|
+
spatio-flux = ["spatio-flux==1.4.0"]
|
|
25
|
+
|
|
26
|
+
[project.scripts]
|
|
27
|
+
newlife = "newlife.cli:main"
|
|
28
|
+
|
|
29
|
+
[build-system]
|
|
30
|
+
requires = ["hatchling"]
|
|
31
|
+
build-backend = "hatchling.build"
|
|
32
|
+
|
|
33
|
+
[tool.uv.sources]
|
|
34
|
+
proofroot = { workspace = true }
|
|
35
|
+
|
|
36
|
+
[tool.hatch.build.targets.wheel]
|
|
37
|
+
packages = ["src/newlife"]
|
|
38
|
+
# 模板与 vendored 的 prereg.sh 不是 .py,必须显式带进 wheel——
|
|
39
|
+
# 「冻结工具不随库发布」是用户拿不到时间证明的直接原因。
|
|
40
|
+
artifacts = ["src/newlife/scaffold/prereg.sh", "src/newlife/scaffold/templates/*",
|
|
41
|
+
"src/newlife/skills/*/SKILL.md"]
|
|
42
|
+
|
|
43
|
+
[dependency-groups]
|
|
44
|
+
dev = ["pytest>=8"]
|
|
45
|
+
|
|
46
|
+
[project.urls]
|
|
47
|
+
Homepage = "https://github.com/hzshen88/newlife"
|
|
48
|
+
Repository = "https://github.com/hzshen88/newlife"
|
|
@@ -0,0 +1,11 @@
|
|
|
1
|
+
"""newlife — a verifiable profile layer for composable biological simulation.
|
|
2
|
+
|
|
3
|
+
Owns the scientific semantics the bare runtime does not provide (proposal
|
|
4
|
+
v0.6, §3): StateClaim / MechanismSpec / Effect / Resolver contracts, path
|
|
5
|
+
authority, read-only alias protection, single-path lowering (the only write
|
|
6
|
+
path into any runtime), and canonical evidence traces.
|
|
7
|
+
|
|
8
|
+
Vendor types (Process, Composite, ...) never leak past the adapter layer;
|
|
9
|
+
`process-bigraph` is an optional extra and may only be imported inside
|
|
10
|
+
`newlife.adapters.process_bigraph`.
|
|
11
|
+
"""
|
|
@@ -0,0 +1 @@
|
|
|
1
|
+
"""adapters subpackage (skeleton — filled per v0.1 schedule; no lowering code before preregistration freeze)."""
|
|
@@ -0,0 +1 @@
|
|
|
1
|
+
"""adapters/process_bigraph subpackage (skeleton — filled per v0.1 schedule; no lowering code before preregistration freeze)."""
|
|
@@ -0,0 +1,144 @@
|
|
|
1
|
+
"""Bare process-bigraph controls that deliberately bypass newlife."""
|
|
2
|
+
|
|
3
|
+
from __future__ import annotations
|
|
4
|
+
|
|
5
|
+
from typing import Any
|
|
6
|
+
|
|
7
|
+
from process_bigraph import Composite, allocate_core
|
|
8
|
+
from process_bigraph.processes.growth_division import Grow
|
|
9
|
+
|
|
10
|
+
|
|
11
|
+
def bare_trajectory(*, initial_mass: float, rate: float, steps: int) -> list[float]:
|
|
12
|
+
"""Run ``Grow`` on bare process-bigraph and return the mass trajectory."""
|
|
13
|
+
core = _core()
|
|
14
|
+
state: dict[str, Any] = {
|
|
15
|
+
"mass": initial_mass,
|
|
16
|
+
"grow": {
|
|
17
|
+
"_type": "process",
|
|
18
|
+
"address": "local:Grow",
|
|
19
|
+
"config": {"rate": rate},
|
|
20
|
+
"inputs": {"mass": ["mass"]},
|
|
21
|
+
"outputs": {"mass": ["mass"]},
|
|
22
|
+
"interval": 1.0,
|
|
23
|
+
},
|
|
24
|
+
}
|
|
25
|
+
composite = Composite({"state": state}, core=core)
|
|
26
|
+
trajectory = [float(composite.state["mass"])]
|
|
27
|
+
for _ in range(steps):
|
|
28
|
+
composite.run(1.0)
|
|
29
|
+
trajectory.append(float(composite.state["mass"]))
|
|
30
|
+
return trajectory
|
|
31
|
+
|
|
32
|
+
|
|
33
|
+
def _core():
|
|
34
|
+
core = allocate_core()
|
|
35
|
+
core.register_link("Grow", Grow)
|
|
36
|
+
return core
|
|
37
|
+
|
|
38
|
+
|
|
39
|
+
# --- 第十六个里程碑:一个真正独立的第三方包(spatio-flux 1.4.0)---
|
|
40
|
+
|
|
41
|
+
|
|
42
|
+
def monod_trajectory(
|
|
43
|
+
*, initial_mass: float, glucose: float, steps: int
|
|
44
|
+
) -> list[tuple[float, dict[str, float]]]:
|
|
45
|
+
"""Run ``MonodKinetics`` on bare process-bigraph and return its trajectory."""
|
|
46
|
+
try:
|
|
47
|
+
import spatio_flux
|
|
48
|
+
from spatio_flux.processes.monod_kinetics import MonodKinetics
|
|
49
|
+
except ImportError as exc:
|
|
50
|
+
raise SystemExit(
|
|
51
|
+
"spatio-flux is not installed; this is an environment error, not a verdict. "
|
|
52
|
+
"Install with: uv sync --package newlife --extra process-bigraph "
|
|
53
|
+
f"--extra spatio-flux. Original error: {exc}"
|
|
54
|
+
) from exc
|
|
55
|
+
|
|
56
|
+
core = allocate_core()
|
|
57
|
+
spatio_flux.register_types(core) # 第三方交付的类型词表
|
|
58
|
+
core.register_link("MonodKinetics", MonodKinetics)
|
|
59
|
+
|
|
60
|
+
state: dict[str, Any] = {
|
|
61
|
+
"mass": initial_mass,
|
|
62
|
+
"local": {"glucose": glucose},
|
|
63
|
+
"exchange": {"glucose": 0.0},
|
|
64
|
+
"kin": {
|
|
65
|
+
"_type": "process",
|
|
66
|
+
"address": "local:MonodKinetics",
|
|
67
|
+
"config": {},
|
|
68
|
+
"inputs": {"biomass": ["mass"], "substrates": ["local"]},
|
|
69
|
+
"outputs": {"biomass": ["mass"], "substrates": ["exchange"]},
|
|
70
|
+
"interval": 1.0,
|
|
71
|
+
},
|
|
72
|
+
}
|
|
73
|
+
composite = Composite({"state": state}, core=core)
|
|
74
|
+
out = [(float(composite.state["mass"]), dict(composite.state["exchange"]))]
|
|
75
|
+
for _ in range(steps):
|
|
76
|
+
composite.run(1.0)
|
|
77
|
+
out.append((float(composite.state["mass"]), dict(composite.state["exchange"])))
|
|
78
|
+
return out
|
|
79
|
+
|
|
80
|
+
|
|
81
|
+
# --- 第十七个里程碑:一个求解器背后的第三方 process(spatio-flux 的 dFBA)---
|
|
82
|
+
|
|
83
|
+
FIELDS = ("glucose", "acetate", "biomass")
|
|
84
|
+
|
|
85
|
+
|
|
86
|
+
def dfba_trajectory(
|
|
87
|
+
*, glucose: float, acetate: float, biomass: float, steps: int
|
|
88
|
+
) -> list[dict[str, float]]:
|
|
89
|
+
"""Run ``DynamicFBA`` on bare process-bigraph with its bundled E. coli model."""
|
|
90
|
+
try:
|
|
91
|
+
import spatio_flux
|
|
92
|
+
from spatio_flux.processes.dfba import MODEL_REGISTRY_DFBA, DynamicFBA
|
|
93
|
+
except ImportError as exc:
|
|
94
|
+
raise SystemExit(
|
|
95
|
+
"spatio-flux or cobra is not installed; this is an environment error, "
|
|
96
|
+
"not a verdict. Install with: uv sync --package newlife "
|
|
97
|
+
f"--extra process-bigraph --extra spatio-flux. Original error: {exc}"
|
|
98
|
+
) from exc
|
|
99
|
+
|
|
100
|
+
core = allocate_core()
|
|
101
|
+
spatio_flux.register_types(core)
|
|
102
|
+
core.register_link("DynamicFBA", DynamicFBA)
|
|
103
|
+
|
|
104
|
+
state: dict[str, Any] = {
|
|
105
|
+
"fields": {"glucose": glucose, "acetate": acetate, "biomass": biomass},
|
|
106
|
+
"fba": {
|
|
107
|
+
"_type": "process",
|
|
108
|
+
"address": "local:DynamicFBA",
|
|
109
|
+
"config": dict(MODEL_REGISTRY_DFBA["ecoli core"]),
|
|
110
|
+
"inputs": {
|
|
111
|
+
"substrates": {"glucose": ["fields", "glucose"],
|
|
112
|
+
"acetate": ["fields", "acetate"]},
|
|
113
|
+
"biomass": ["fields", "biomass"],
|
|
114
|
+
},
|
|
115
|
+
"outputs": {
|
|
116
|
+
"substrates": {"glucose": ["fields", "glucose"],
|
|
117
|
+
"acetate": ["fields", "acetate"]},
|
|
118
|
+
"biomass": ["fields", "biomass"],
|
|
119
|
+
},
|
|
120
|
+
"interval": 1.0,
|
|
121
|
+
},
|
|
122
|
+
}
|
|
123
|
+
composite = Composite({"state": state}, core=core)
|
|
124
|
+
out = [normalise_fields(composite.state["fields"])]
|
|
125
|
+
for _ in range(steps):
|
|
126
|
+
composite.run(1.0)
|
|
127
|
+
out.append(normalise_fields(composite.state["fields"]))
|
|
128
|
+
return out
|
|
129
|
+
|
|
130
|
+
|
|
131
|
+
def normalise_fields(fields: Any) -> dict[str, float]:
|
|
132
|
+
"""Normalize third-party numeric scalar values to Python ``float``."""
|
|
133
|
+
return {k: float(fields[k]) for k in FIELDS}
|
|
134
|
+
|
|
135
|
+
|
|
136
|
+
def solver_identity() -> dict[str, str]:
|
|
137
|
+
"""Return the optimization interface and solver version used by dFBA."""
|
|
138
|
+
from cobra.io import load_model
|
|
139
|
+
import swiglpk
|
|
140
|
+
|
|
141
|
+
return {
|
|
142
|
+
"optlang_interface": load_model("textbook").solver.interface.__name__,
|
|
143
|
+
"glpk_version": str(swiglpk.glp_version()),
|
|
144
|
+
}
|