gsMap 1.71.2__tar.gz → 1.73.0__tar.gz
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- gsmap-1.73.0/.coveragerc +41 -0
- gsmap-1.73.0/.github/workflows/docs.yml +55 -0
- gsmap-1.73.0/.github/workflows/publish-to-pypi.yml +97 -0
- gsmap-1.73.0/.github/workflows/test_linux.yml +88 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/.gitignore +0 -10
- gsmap-1.73.0/.markdownlint.yaml +20 -0
- gsmap-1.73.0/.pre-commit-config.yaml +66 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/LICENSE +6 -6
- gsmap-1.73.0/PKG-INFO +169 -0
- gsmap-1.73.0/README.md +104 -0
- gsmap-1.73.0/codecov.yml +29 -0
- gsmap-1.73.0/docs/source/advanced_usage.md +117 -0
- gsmap-1.73.0/docs/source/api/create_slice_mean.rst +8 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/quick_mode.rst +1 -1
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api.rst +6 -2
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/conf.py +21 -23
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/data.rst +4 -4
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/data_format.md +25 -19
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/index.rst +3 -4
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/install.rst +3 -2
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/quick_mode.md +8 -4
- gsmap-1.71.2/docs/source/mouse_example.md → gsmap-1.73.0/docs/source/step_by_step.md +15 -45
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/tutorials.rst +2 -1
- gsmap-1.73.0/pyproject.toml +187 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/GNN/adjacency_matrix.py +25 -27
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/GNN/model.py +9 -7
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/GNN/train.py +8 -11
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/__init__.py +3 -3
- gsmap-1.73.0/src/gsMap/__main__.py +4 -0
- gsmap-1.73.0/src/gsMap/cauchy_combination_test.py +144 -0
- gsmap-1.73.0/src/gsMap/config.py +1432 -0
- gsmap-1.73.0/src/gsMap/create_slice_mean.py +168 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/diagnosis.py +179 -101
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/find_latent_representation.py +29 -27
- gsmap-1.73.0/src/gsMap/format_sumstats.py +445 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/generate_ldscore.py +334 -222
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/latent_to_gene.py +128 -68
- gsmap-1.73.0/src/gsMap/main.py +40 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/report.py +39 -25
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/run_all_mode.py +87 -46
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/setup.py +1 -1
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/spatial_ldsc_multiple_sumstats.py +154 -80
- gsmap-1.73.0/src/gsMap/utils/generate_r2_matrix.py +489 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/utils/jackknife.py +84 -80
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/utils/manhattan_plot.py +180 -207
- gsmap-1.73.0/src/gsMap/utils/regression_read.py +201 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/visualize.py +82 -64
- gsmap-1.73.0/tests/conftest.py +245 -0
- gsmap-1.73.0/tests/test_advanced_usage.py +228 -0
- gsmap-1.73.0/tests/test_cli.py +231 -0
- gsmap-1.73.0/tests/test_docs_cli_parsing.py +125 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/conf.py +19 -20
- gsmap-1.71.2/.github/workflows/publish-to-pypi.yml +0 -96
- gsmap-1.71.2/PKG-INFO +0 -105
- gsmap-1.71.2/README.md +0 -46
- gsmap-1.71.2/docs/source/charts/cortex/Cortex_151507_Height.json +0 -1
- gsmap-1.71.2/docs/source/charts/cortex/Cortex_151507_IQ.json +0 -1
- gsmap-1.71.2/docs/source/charts/cortex/Cortex_151507_MCHC.json +0 -1
- gsmap-1.71.2/docs/source/charts/cortex/Cortex_151507_SCZ.json +0 -1
- gsmap-1.71.2/docs/source/charts/mouse_embryo/E16.5_E1S1_Height.json +0 -1
- gsmap-1.71.2/docs/source/charts/mouse_embryo/E16.5_E1S1_IQ.json +0 -1
- gsmap-1.71.2/docs/source/charts/mouse_embryo/E16.5_E1S1_MCHC.json +0 -1
- gsmap-1.71.2/docs/source/charts/mouse_embryo/E16.5_E1S1_SCZ.json +0 -1
- gsmap-1.71.2/docs/source/charts/test.json +0 -16
- gsmap-1.71.2/docs/source/mouse.rst +0 -5
- gsmap-1.71.2/pyproject.toml +0 -83
- gsmap-1.71.2/src/gsMap/__main__.py +0 -3
- gsmap-1.71.2/src/gsMap/cauchy_combination_test.py +0 -141
- gsmap-1.71.2/src/gsMap/config.py +0 -806
- gsmap-1.71.2/src/gsMap/format_sumstats.py +0 -407
- gsmap-1.71.2/src/gsMap/main.py +0 -31
- gsmap-1.71.2/src/gsMap/utils/generate_r2_matrix.py +0 -735
- gsmap-1.71.2/src/gsMap/utils/make_annotations.py +0 -518
- gsmap-1.71.2/src/gsMap/utils/regression_read.py +0 -294
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/Makefile +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/make.bat +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/requirements.txt +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/_static/schematic.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/cauchy_combination.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/find_latent_representations.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/format_sumstats.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/generate_ldscore.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/latent_to_gene.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/report.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/api/spatial_ldsc.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/docs/source/release.rst +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/schematic.png +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/GNN/__init__.py +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/templates/report_template.html +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/src/gsMap/utils/__init__.py +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/Makefile +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/make.bat +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/requirements.txt +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/_static/raw1_add_txt.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/_static/raw2_add_txt.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/_static/raw3_add_txt.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/_static/raw4_add_txt.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/_static/raw5_add_txt.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/_static/schematic.svg +0 -0
- {gsmap-1.71.2 → gsmap-1.73.0}/visualization_web_docs/source/index.rst +0 -0
gsmap-1.73.0/.coveragerc
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[run]
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source = src/gsMap
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omit =
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# Exclude the files you mentioned
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src/gsMap/utils/jackknife.py
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src/gsMap/format_sumstats.py
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# Other files you might want to exclude
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*/tests/*
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*/__init__.py
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src/gsMap/templates/*
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# Additional excludes
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src/gsMap/__main__.py
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src/gsMap/setup.py
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[report]
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exclude_lines =
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# Have to re-enable the standard pragma
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pragma: no cover
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def __repr__
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if self\.debug
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# Don't complain if tests don't hit defensive assertion code
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raise NotImplementedError
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raise ValueError
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except ImportError
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except Exception
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except:
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if 0:
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if False:
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# Skip pass statements
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pass
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[paths]
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source =
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src/gsMap
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name: docs
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on:
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push:
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paths:
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jobs:
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deploy_docs:
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runs-on: self-hosted
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steps:
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- name: Checkout code
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uses: actions/checkout@v4
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- name: Set up Python
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uses: actions/setup-python@v4
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with:
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python-version: "3.12"
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# --- Build 'docs' documentation ---
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run: |
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python -m pip install '.[doc]'
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working-directory: ./docs
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make html
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DOCS_OUTPUT_DIR="/mnt/website_docs/gsmap" # Adjust if you want a different subfolder
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mkdir -p "$DOCS_OUTPUT_DIR"
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rsync -avz ./docs/build/html/ "$DOCS_OUTPUT_DIR/"
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echo "Documentation for 'docs' deployed to: $DOCS_OUTPUT_DIR"
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# # --- Build 'visualization_web_docs' documentation ---
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# working-directory: ./visualization_web_docs
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# python -m pip install -r requirements.txt
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#
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# working-directory: ./visualization_web_docs
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# run: |
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# make html
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# DOCS_OUTPUT_DIR="/mnt/website_docs/visualization_web_docs" # Deploy to a separate folder
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# rsync -avz ./visualization_web_docs/build/html/ "$DOCS_OUTPUT_DIR/"
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# echo "Documentation for 'visualization_web_docs' deployed to: $DOCS_OUTPUT_DIR"
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name: Publish Python 🐍 distribution 📦 to PyPI and TestPyPI
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on: push
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jobs:
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runs-on: ubuntu-latest
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with:
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python-version: "3.x"
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python3 -m
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pip install
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flit build
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name: >-
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Publish Python 🐍 distribution 📦 to PyPI
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if: startsWith(github.ref, 'refs/tags/') # only publish to PyPI on tag pushes
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needs:
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- build
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runs-on: ubuntu-latest
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environment:
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name: pypi
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url: https://pypi.org/p/gsMap
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permissions:
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id-token: write # IMPORTANT: mandatory for trusted publishing
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path: dist/
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github-release:
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name: >-
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Sign the Python 🐍 distribution 📦 with Sigstore
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and upload them to GitHub Release
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needs:
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contents: write # IMPORTANT: mandatory for making GitHub Releases
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branches: [main, "[0-9]+.[0-9]+.x"]
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pull_request:
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schedule:
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workflow_dispatch:
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concurrency:
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group: ${{ github.workflow }}-${{ github.ref }}
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cancel-in-progress: true
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test:
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defaults:
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run:
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shell: bash -e {0} # -e to fail on error
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strategy:
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fail-fast: false
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matrix:
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python: ["3.10", "3.13"]
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name: Python ${{ matrix.python }} integration
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env:
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PYTHON: ${{ matrix.python }}
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TEST_DATA_DIR: /gsmap_test_data
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minimum_pre_commit_version: 2.16.0
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- repo: https://github.com/asottile/blacken-docs
|
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hooks:
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rev: v5.0.0
|
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|
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- id: check-ast
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args: [--fix=lf]
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entry: |
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Cannot commit .rej files. These indicate merge conflicts that arise during automated template updates.
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files: '.*\.rej$'
|
@@ -1,6 +1,6 @@
|
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MIT License
|
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Copyright (c)
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Copyright (c) 2025 JianYang-Lab
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Permission is hereby granted, free of charge, to any person obtaining a copy
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of this software and associated documentation files (the "Software"), to deal
|
@@ -9,13 +9,13 @@ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
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copies of the Software, and to permit persons to whom the Software is
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The above copyright notice and this permission notice shall be included in
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The above copyright notice and this permission notice shall be included in all
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copies or substantial portions of the Software.
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THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
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AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
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LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
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OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
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OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
|
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SOFTWARE.
|
gsmap-1.73.0/PKG-INFO
ADDED
@@ -0,0 +1,169 @@
|
|
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|
+
Metadata-Version: 2.4
|
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Name: gsMap
|
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Version: 1.73.0
|
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Summary: Genetics-informed pathogenic spatial mapping
|
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Author-email: liyang <songliyang@westlake.edu.cn>, wenhao <chenwenhao@westlake.edu.cn>
|
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Requires-Python: >=3.10
|
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Description-Content-Type: text/markdown
|
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Classifier: Development Status :: 3 - Alpha
|
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Classifier: Intended Audience :: Developers
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Classifier: License :: OSI Approved :: MIT License
|
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Classifier: Programming Language :: Python :: 3.10
|
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Classifier: Programming Language :: Python :: 3.11
|
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Classifier: Programming Language :: Python :: 3.12
|
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Classifier: Operating System :: POSIX :: Linux
|
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License-File: LICENSE
|
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Requires-Dist: numpy < 2.0.0
|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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|
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Requires-Dist: sphinxcontrib-serializinghtml ; extra == "doc"
|
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Requires-Dist: furo ; extra == "doc"
|
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|
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|
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|
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|
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|
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Requires-Dist: pytest-cov>=4.0.0 ; extra == "tests"
|
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Requires-Dist: coverage ; extra == "tests"
|
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|
+
Project-URL: Documentation, https://yanglab.westlake.edu.cn/gsmap/document/software
|
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|
+
Project-URL: Home, https://github.com/JianYang-Lab/gsMap
|
61
|
+
Project-URL: Website, https://yanglab.westlake.edu.cn/gsmap/home
|
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|
+
Provides-Extra: doc
|
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|
+
Provides-Extra: tests
|
64
|
+
|
65
|
+
# gsMap
|
66
|
+
|
67
|
+
| | | | |
|
68
|
+
| ------------- | ---------------------------------------------------------------------------------------------------- | -------------- | -------------------------------------------------------------------------------------------------- |
|
69
|
+
| __Version__ | [![PyPI version][pypi-badge]][pypi-url] [![Python][python-badge]][python-url] | __Status__ | [![Project Status][status-badge]][status-url] [![Maintenance][maintenance-badge]][maintenance-url] |
|
70
|
+
| __Activity__ | [![GitHub commits][commits-badge]][commits-url] [![Last Commit][last-commit-badge]][last-commit-url] | __Quality__ | [![codecov][codecov-badge]][codecov-url] [![Ruff][ruff-badge]][ruff-url] |
|
71
|
+
| __CI/CD__ | [![Docs][docs-badge]][docs-url] [![test][test-badge]][test-url] | __Community__ | [![GitHub stars][stars-badge]][stars-url] [![GitHub forks][forks-badge]][forks-url] |
|
72
|
+
| __Downloads__ | [![Downloads][downloads-badge]][downloads-url] | __License__ | [![License: MIT][license-badge]][license-url] [![DOI][doi-badge]][doi-url] |
|
73
|
+
| __Platform__ | [![Linux][linux-badge]][linux-url] | __Contribute__ | [![Issues][issues-badge]][issues-url] [![PRs Welcome][pr-badge]][pr-url] |
|
74
|
+
|
75
|
+
## Introduction
|
76
|
+
|
77
|
+
`gsMap` (genetically informed spatial mapping of cells for complex traits)
|
78
|
+
integrates spatial transcriptomics (ST) data with genome-wide association study (GWAS)
|
79
|
+
summary statistics to map cells to human complex traits, including diseases,
|
80
|
+
in a spatially resolved manner.
|
81
|
+
|
82
|
+
## Key Features
|
83
|
+
|
84
|
+
- __Spatially-aware High-Resolution Trait Mapping__
|
85
|
+
- __Spatial Region Identification__
|
86
|
+
- __Putative Causal Genes Identification__
|
87
|
+
|
88
|
+

|
89
|
+
|
90
|
+
## Installation
|
91
|
+
|
92
|
+
Install using pip:
|
93
|
+
|
94
|
+
```bash
|
95
|
+
conda create -n gsMap python>=3.10
|
96
|
+
conda activate gsMap
|
97
|
+
pip install gsMap
|
98
|
+
```
|
99
|
+
|
100
|
+
Install from source:
|
101
|
+
|
102
|
+
```bash
|
103
|
+
git clone https://github.com/JianYang-Lab/gsMap
|
104
|
+
cd gsMap
|
105
|
+
pip install -e .
|
106
|
+
```
|
107
|
+
|
108
|
+
Verify the installation by running the following command:
|
109
|
+
|
110
|
+
```bash
|
111
|
+
gsmap --help
|
112
|
+
```
|
113
|
+
|
114
|
+
## Usage
|
115
|
+
|
116
|
+
Please check out the documentation and tutorials at [gsMap Documentation](https://yanglab.westlake.edu.cn/gsmap/document/software).
|
117
|
+
|
118
|
+
## Online Visualization
|
119
|
+
|
120
|
+
To visualize the traits-cell association spatial maps,
|
121
|
+
please refer to [gsMap Visualization](https://yanglab.westlake.edu.cn/gsmap/visualize).
|
122
|
+
|
123
|
+
## Citation
|
124
|
+
|
125
|
+
Song, L., Chen, W., Hou, J., Guo, M. & Yang, J.
|
126
|
+
[Spatially resolved mapping of cells associated with human complex traits.](https://doi.org/10.1038/s41586-025-08757-x)
|
127
|
+
Nature (2025).
|
128
|
+
|
129
|
+
Please cite the paper and give us a STAR if you find gsMap useful for your research.
|
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|
+
|
131
|
+
<!-- Badge links -->
|
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|
+
|
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|
+
[codecov-badge]: https://codecov.io/gh/JianYang-Lab/gsMap/graph/badge.svg?token=NFZFXZIEUU
|
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[codecov-url]: https://codecov.io/gh/JianYang-Lab/gsMap
|
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[commits-badge]: https://img.shields.io/github/commit-activity/m/JianYang-Lab/gsMap
|
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[commits-url]: https://github.com/JianYang-Lab/gsMap/commits/main
|
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[docs-badge]: https://github.com/JianYang-Lab/gsMap/actions/workflows/docs.yml/badge.svg
|
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[docs-url]: https://github.com/JianYang-Lab/gsMap/actions/workflows/docs.yml
|
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[doi-badge]: https://img.shields.io/badge/DOI-10.1038%2Fs41586--025--08757--x-blue
|
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|
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[doi-url]: https://doi.org/10.1038/s41586-025-08757-x
|
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|
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[downloads-badge]: https://static.pepy.tech/badge/gsMap
|
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|
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[downloads-url]: https://pepy.tech/project/gsMap
|
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|
+
[forks-badge]: https://img.shields.io/github/forks/JianYang-Lab/gsMap
|
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|
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[forks-url]: https://github.com/JianYang-Lab/gsMap/network/members
|
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|
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[issues-badge]: https://img.shields.io/github/issues/JianYang-Lab/gsMap
|
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|
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[issues-url]: https://github.com/JianYang-Lab/gsMap/issues
|
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|
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[last-commit-badge]: https://img.shields.io/github/last-commit/JianYang-Lab/gsMap
|
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[last-commit-url]: https://github.com/JianYang-Lab/gsMap/commits/main
|
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|
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[license-badge]: https://img.shields.io/badge/License-MIT-yellow.svg
|
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|
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[license-url]: https://opensource.org/licenses/MIT
|
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|
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[linux-badge]: https://img.shields.io/badge/Linux-%E2%9C%93-success
|
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|
+
[linux-url]: https://github.com/JianYang-Lab/gsMap/actions/workflows/test_linux.yml
|
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|
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[maintenance-badge]: https://img.shields.io/badge/Maintained%3F-yes-green.svg
|
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[pr-url]: https://github.com/JianYang-Lab/gsMap/pulls
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[pypi-badge]: https://img.shields.io/pypi/v/gsMap
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[pypi-url]: https://pypi.org/project/gsMap/
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[python-badge]: https://img.shields.io/pypi/pyversions/gsMap
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[python-url]: https://www.python.org
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[ruff-badge]: https://img.shields.io/endpoint?url=https://raw.githubusercontent.com/astral-sh/ruff/main/assets/badge/v2.json
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[stars-badge]: https://img.shields.io/github/stars/JianYang-Lab/gsMap
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[status-badge]: https://www.repostatus.org/badges/latest/active.svg
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