gsMap 1.60__tar.gz
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- gsmap-1.60/.github/workflows/publish-to-pypi.yml +120 -0
- gsmap-1.60/.github/workflows/sphinx.yml +24 -0
- gsmap-1.60/.gitignore +257 -0
- gsmap-1.60/LICENSE +21 -0
- gsmap-1.60/PKG-INFO +124 -0
- gsmap-1.60/README.md +70 -0
- gsmap-1.60/docs/Makefile +20 -0
- gsmap-1.60/docs/make.bat +35 -0
- gsmap-1.60/docs/requirements.txt +2 -0
- gsmap-1.60/docs/source/_static/architecture.svg +1 -0
- gsmap-1.60/docs/source/api/cauchy_combination.rst +8 -0
- gsmap-1.60/docs/source/api/find_latent_representations.rst +8 -0
- gsmap-1.60/docs/source/api/format_sumstats.rst +7 -0
- gsmap-1.60/docs/source/api/generate_ldscore.rst +8 -0
- gsmap-1.60/docs/source/api/latent_to_gene.rst +8 -0
- gsmap-1.60/docs/source/api/spatial_ldsc.rst +8 -0
- gsmap-1.60/docs/source/api/visualization.rst +8 -0
- gsmap-1.60/docs/source/api.rst +86 -0
- gsmap-1.60/docs/source/charts/cortex/Cortex_151507_Height.json +1 -0
- gsmap-1.60/docs/source/charts/cortex/Cortex_151507_IQ.json +1 -0
- gsmap-1.60/docs/source/charts/cortex/Cortex_151507_MCHC.json +1 -0
- gsmap-1.60/docs/source/charts/cortex/Cortex_151507_SCZ.json +1 -0
- gsmap-1.60/docs/source/charts/mouse_embryo/E16.5_E1S1_Height.json +1 -0
- gsmap-1.60/docs/source/charts/mouse_embryo/E16.5_E1S1_IQ.json +1 -0
- gsmap-1.60/docs/source/charts/mouse_embryo/E16.5_E1S1_MCHC.json +1 -0
- gsmap-1.60/docs/source/charts/mouse_embryo/E16.5_E1S1_SCZ.json +1 -0
- gsmap-1.60/docs/source/charts/test.json +16 -0
- gsmap-1.60/docs/source/conf.py +55 -0
- gsmap-1.60/docs/source/data.rst +62 -0
- gsmap-1.60/docs/source/data_format.md +120 -0
- gsmap-1.60/docs/source/index.rst +72 -0
- gsmap-1.60/docs/source/install.rst +24 -0
- gsmap-1.60/docs/source/mouse.rst +26 -0
- gsmap-1.60/docs/source/mouse_example.md +389 -0
- gsmap-1.60/docs/source/release.rst +7 -0
- gsmap-1.60/docs/source/tutorials.rst +27 -0
- gsmap-1.60/pyproject.toml +73 -0
- gsmap-1.60/src/gsMap/GNN_VAE/__init__.py +0 -0
- gsmap-1.60/src/gsMap/GNN_VAE/adjacency_matrix.py +95 -0
- gsmap-1.60/src/gsMap/GNN_VAE/model.py +87 -0
- gsmap-1.60/src/gsMap/GNN_VAE/train.py +97 -0
- gsmap-1.60/src/gsMap/__init__.py +5 -0
- gsmap-1.60/src/gsMap/__main__.py +3 -0
- gsmap-1.60/src/gsMap/cauchy_combination_test.py +163 -0
- gsmap-1.60/src/gsMap/config.py +734 -0
- gsmap-1.60/src/gsMap/find_latent_representation.py +209 -0
- gsmap-1.60/src/gsMap/format_sumstats.py +410 -0
- gsmap-1.60/src/gsMap/generate_ldscore.py +551 -0
- gsmap-1.60/src/gsMap/generate_r2_matrix.py +743 -0
- gsmap-1.60/src/gsMap/jackknife.py +514 -0
- gsmap-1.60/src/gsMap/latent_to_gene.py +257 -0
- gsmap-1.60/src/gsMap/main.py +39 -0
- gsmap-1.60/src/gsMap/make_annotations.py +560 -0
- gsmap-1.60/src/gsMap/regression_read.py +294 -0
- gsmap-1.60/src/gsMap/spatial_ldsc_multiple_sumstats.py +307 -0
- gsmap-1.60/src/gsMap/visualize.py +154 -0
- gsmap-1.60/test/GPS-snakemake-workflow-macaque.smk +268 -0
- gsmap-1.60/test/GPS-snakemake-workflow.smk +229 -0
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gsmap-1.60/.gitignore
ADDED
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### JetBrains+all template
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# Covers JetBrains IDEs: IntelliJ, RubyMine, PhpStorm, AppCode, PyCharm, CLion, Android Studio, WebStorm and Rider
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# install all needed dependencies.
|
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+
#Pipfile.lock
|
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|
+
|
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|
+
# poetry
|
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|
+
# Similar to Pipfile.lock, it is generally recommended to include poetry.lock in version control.
|
193
|
+
# This is especially recommended for binary packages to ensure reproducibility, and is more
|
194
|
+
# commonly ignored for libraries.
|
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|
+
# https://python-poetry.org/docs/basic-usage/#commit-your-poetrylock-file-to-version-control
|
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|
+
#poetry.lock
|
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|
+
|
198
|
+
# pdm
|
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|
+
# Similar to Pipfile.lock, it is generally recommended to include pdm.lock in version control.
|
200
|
+
#pdm.lock
|
201
|
+
# pdm stores project-wide configurations in .pdm.toml, but it is recommended to not include it
|
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|
+
# in version control.
|
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|
+
# https://pdm.fming.dev/#use-with-ide
|
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|
+
.pdm.toml
|
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+
|
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|
+
# PEP 582; used by e.g. github.com/David-OConnor/pyflow and github.com/pdm-project/pdm
|
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|
+
__pypackages__/
|
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+
|
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|
+
# Celery stuff
|
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|
+
celerybeat-schedule
|
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|
+
celerybeat.pid
|
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+
|
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+
# SageMath parsed files
|
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+
*.sage.py
|
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+
|
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|
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# Environments
|
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.env
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.venv
|
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env/
|
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+
venv/
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+
ENV/
|
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|
+
env.bak/
|
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+
venv.bak/
|
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+
|
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|
+
# Spyder project settings
|
226
|
+
.spyderproject
|
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+
.spyproject
|
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+
|
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|
+
# Rope project settings
|
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+
.ropeproject
|
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+
|
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# mkdocs documentation
|
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|
+
/site
|
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+
|
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|
+
# mypy
|
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|
+
.mypy_cache/
|
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+
.dmypy.json
|
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|
+
dmypy.json
|
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+
|
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|
+
# Pyre type checker
|
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|
+
.pyre/
|
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|
+
|
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|
+
# pytype static type analyzer
|
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|
+
.pytype/
|
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+
|
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|
+
# Cython debug symbols
|
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|
+
cython_debug/
|
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|
+
|
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|
+
test/
|
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|
+
# PyCharm
|
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|
+
# JetBrains specific template is maintained in a separate JetBrains.gitignore that can
|
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|
+
# be found at https://github.com/github/gitignore/blob/main/Global/JetBrains.gitignore
|
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|
+
# and can be added to the global gitignore or merged into this file. For a more nuclear
|
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|
+
# option (not recommended) you can uncomment the following to ignore the entire idea folder.
|
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|
+
#.idea/
|
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|
+
|
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|
+
!/test/GPS-snakemake-workflow.smk
|
gsmap-1.60/LICENSE
ADDED
@@ -0,0 +1,21 @@
|
|
1
|
+
The MIT License (MIT)
|
2
|
+
|
3
|
+
Copyright (c) 2023 liyang
|
4
|
+
|
5
|
+
Permission is hereby granted, free of charge, to any person obtaining a copy
|
6
|
+
of this software and associated documentation files (the "Software"), to deal
|
7
|
+
in the Software without restriction, including without limitation the rights
|
8
|
+
to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
|
9
|
+
copies of the Software, and to permit persons to whom the Software is
|
10
|
+
furnished to do so, subject to the following conditions:
|
11
|
+
|
12
|
+
The above copyright notice and this permission notice shall be included in
|
13
|
+
all copies or substantial portions of the Software.
|
14
|
+
|
15
|
+
THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
|
16
|
+
IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
|
17
|
+
FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
|
18
|
+
AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
|
19
|
+
LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
|
20
|
+
OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
|
21
|
+
THE SOFTWARE.
|
gsmap-1.60/PKG-INFO
ADDED
@@ -0,0 +1,124 @@
|
|
1
|
+
Metadata-Version: 2.1
|
2
|
+
Name: gsMap
|
3
|
+
Version: 1.60
|
4
|
+
Summary: Genetics-informed pathogenic spatial mapping
|
5
|
+
Author-email: liyang <songliyang@westlake.edu.cn>, wenhao <chenwenhao@westlake.edu.cn>
|
6
|
+
Requires-Python: >=3.8
|
7
|
+
Description-Content-Type: text/markdown
|
8
|
+
Classifier: Development Status :: 3 - Alpha
|
9
|
+
Classifier: Intended Audience :: Developers
|
10
|
+
Classifier: License :: OSI Approved :: MIT License
|
11
|
+
Classifier: Programming Language :: Python :: 3.8
|
12
|
+
Classifier: Programming Language :: Python :: 3.9
|
13
|
+
Classifier: Operating System :: POSIX :: Linux
|
14
|
+
Requires-Dist: numpy
|
15
|
+
Requires-Dist: pandas
|
16
|
+
Requires-Dist: scipy
|
17
|
+
Requires-Dist: scikit-learn
|
18
|
+
Requires-Dist: matplotlib
|
19
|
+
Requires-Dist: seaborn
|
20
|
+
Requires-Dist: tqdm
|
21
|
+
Requires-Dist: progress
|
22
|
+
Requires-Dist: pyyaml
|
23
|
+
Requires-Dist: torch
|
24
|
+
Requires-Dist: torch-geometric
|
25
|
+
Requires-Dist: pyranges
|
26
|
+
Requires-Dist: pyfiglet
|
27
|
+
Requires-Dist: plotly
|
28
|
+
Requires-Dist: kaleido
|
29
|
+
Requires-Dist: sphinx ; extra == "doc"
|
30
|
+
Requires-Dist: sphinx-argparse ; extra == "doc"
|
31
|
+
Requires-Dist: sphinx-autobuild ; extra == "doc"
|
32
|
+
Requires-Dist: sphinx-autodoc-typehints ; extra == "doc"
|
33
|
+
Requires-Dist: sphinx-basic-ng ; extra == "doc"
|
34
|
+
Requires-Dist: sphinx-charts ; extra == "doc"
|
35
|
+
Requires-Dist: sphinx-copybutton ; extra == "doc"
|
36
|
+
Requires-Dist: sphinx_inline_tabs ; extra == "doc"
|
37
|
+
Requires-Dist: sphinx-markdown-tables ; extra == "doc"
|
38
|
+
Requires-Dist: sphinx-rtd-theme ; extra == "doc"
|
39
|
+
Requires-Dist: sphinxcontrib-applehelp ; extra == "doc"
|
40
|
+
Requires-Dist: sphinxcontrib-devhelp ; extra == "doc"
|
41
|
+
Requires-Dist: sphinxcontrib-htmlhelp ; extra == "doc"
|
42
|
+
Requires-Dist: sphinxcontrib-jquery ; extra == "doc"
|
43
|
+
Requires-Dist: sphinxcontrib-jsmath ; extra == "doc"
|
44
|
+
Requires-Dist: sphinxcontrib-qthelp ; extra == "doc"
|
45
|
+
Requires-Dist: sphinxcontrib-serializinghtml ; extra == "doc"
|
46
|
+
Requires-Dist: furo ; extra == "doc"
|
47
|
+
Requires-Dist: myst-parser ; extra == "doc"
|
48
|
+
Requires-Dist: nbsphinx ; extra == "doc"
|
49
|
+
Project-URL: Documentation, https://...
|
50
|
+
Project-URL: Home, https://github.com/LeonSong1995/gsMap
|
51
|
+
Project-URL: Website, https://...
|
52
|
+
Provides-Extra: doc
|
53
|
+
|
54
|
+
# gsMap (genetically informed spatial mapping of cells for complex traits)
|
55
|
+
[](https://github.com/LeonSong1995/gsMap/stargazers)
|
56
|
+
[](https://opensource.org/licenses/MIT)
|
57
|
+
|
58
|
+
|
59
|
+
## Features
|
60
|
+
|
61
|
+
....
|
62
|
+
|
63
|
+
## Installation
|
64
|
+
|
65
|
+
install use pip:
|
66
|
+
|
67
|
+
```bash
|
68
|
+
pip install gsMap-mapping
|
69
|
+
```
|
70
|
+
|
71
|
+
install from source:
|
72
|
+
|
73
|
+
```bash
|
74
|
+
git clone
|
75
|
+
cd gsMap-mapping
|
76
|
+
pip install -e .
|
77
|
+
```
|
78
|
+
|
79
|
+
## Usage
|
80
|
+
|
81
|
+
To use gsMap, navigate to the command line and enter `gsMap` followed by the subcommand that corresponds to the desired operation. Each subcommand may require specific arguments to run.
|
82
|
+
|
83
|
+
### Basic Command Structure
|
84
|
+
|
85
|
+
```bash
|
86
|
+
gsMap subcommand [arguments...]
|
87
|
+
```
|
88
|
+
|
89
|
+
- `subcommand`: The specific operation you wish to perform.
|
90
|
+
- `arguments`: The arguments and options required for the subcommand.
|
91
|
+
|
92
|
+
### Available Subcommands
|
93
|
+
|
94
|
+
(Provide a list and brief description of each available subcommand. For example:)
|
95
|
+
|
96
|
+
- `run_find_latent_representations`: Finds latent representations using a GNN-VAE model.
|
97
|
+
- `run_latent_to_gene`: Maps latent representations to gene markers.
|
98
|
+
- `run_generate_ldscore`: Generates LD scores for genomic spots.
|
99
|
+
- `run_spatial_ldsc`: Conducts spatial LDSC analysis.
|
100
|
+
- `run_cauchy_combination`: Performs Cauchy combination tests for annotations.
|
101
|
+
- `run_all_mode`: Executes a comprehensive pipeline covering all steps.
|
102
|
+
|
103
|
+
### Examples
|
104
|
+
|
105
|
+
To run a specific functionality, you need to provide the appropriate subcommand and arguments. For example:
|
106
|
+
### Running Requirement
|
107
|
+
|
108
|
+
|
109
|
+
```bash
|
110
|
+
gsMap run_find_latent_representations --input_hdf5_path <path> --output_hdf5_path <path> --sample_name <name>
|
111
|
+
```
|
112
|
+
|
113
|
+
This command initiates the process of finding latent representations based on the given HDF5 input and output paths and sample name.
|
114
|
+
|
115
|
+
## Contributing
|
116
|
+
|
117
|
+
...
|
118
|
+
|
119
|
+
## License
|
120
|
+
|
121
|
+
....
|
122
|
+
|
123
|
+
---
|
124
|
+
|
gsmap-1.60/README.md
ADDED
@@ -0,0 +1,70 @@
|
|
1
|
+
# gsMap (genetically informed spatial mapping of cells for complex traits)
|
2
|
+
[](https://github.com/LeonSong1995/gsMap/stargazers)
|
3
|
+
[](https://opensource.org/licenses/MIT)
|
4
|
+
|
5
|
+
|
6
|
+
## Features
|
7
|
+
|
8
|
+
....
|
9
|
+
|
10
|
+
## Installation
|
11
|
+
|
12
|
+
install use pip:
|
13
|
+
|
14
|
+
```bash
|
15
|
+
pip install gsMap-mapping
|
16
|
+
```
|
17
|
+
|
18
|
+
install from source:
|
19
|
+
|
20
|
+
```bash
|
21
|
+
git clone
|
22
|
+
cd gsMap-mapping
|
23
|
+
pip install -e .
|
24
|
+
```
|
25
|
+
|
26
|
+
## Usage
|
27
|
+
|
28
|
+
To use gsMap, navigate to the command line and enter `gsMap` followed by the subcommand that corresponds to the desired operation. Each subcommand may require specific arguments to run.
|
29
|
+
|
30
|
+
### Basic Command Structure
|
31
|
+
|
32
|
+
```bash
|
33
|
+
gsMap subcommand [arguments...]
|
34
|
+
```
|
35
|
+
|
36
|
+
- `subcommand`: The specific operation you wish to perform.
|
37
|
+
- `arguments`: The arguments and options required for the subcommand.
|
38
|
+
|
39
|
+
### Available Subcommands
|
40
|
+
|
41
|
+
(Provide a list and brief description of each available subcommand. For example:)
|
42
|
+
|
43
|
+
- `run_find_latent_representations`: Finds latent representations using a GNN-VAE model.
|
44
|
+
- `run_latent_to_gene`: Maps latent representations to gene markers.
|
45
|
+
- `run_generate_ldscore`: Generates LD scores for genomic spots.
|
46
|
+
- `run_spatial_ldsc`: Conducts spatial LDSC analysis.
|
47
|
+
- `run_cauchy_combination`: Performs Cauchy combination tests for annotations.
|
48
|
+
- `run_all_mode`: Executes a comprehensive pipeline covering all steps.
|
49
|
+
|
50
|
+
### Examples
|
51
|
+
|
52
|
+
To run a specific functionality, you need to provide the appropriate subcommand and arguments. For example:
|
53
|
+
### Running Requirement
|
54
|
+
|
55
|
+
|
56
|
+
```bash
|
57
|
+
gsMap run_find_latent_representations --input_hdf5_path <path> --output_hdf5_path <path> --sample_name <name>
|
58
|
+
```
|
59
|
+
|
60
|
+
This command initiates the process of finding latent representations based on the given HDF5 input and output paths and sample name.
|
61
|
+
|
62
|
+
## Contributing
|
63
|
+
|
64
|
+
...
|
65
|
+
|
66
|
+
## License
|
67
|
+
|
68
|
+
....
|
69
|
+
|
70
|
+
---
|
gsmap-1.60/docs/Makefile
ADDED
@@ -0,0 +1,20 @@
|
|
1
|
+
# Minimal makefile for Sphinx documentation
|
2
|
+
#
|
3
|
+
|
4
|
+
# You can set these variables from the command line, and also
|
5
|
+
# from the environment for the first two.
|
6
|
+
SPHINXOPTS ?=
|
7
|
+
SPHINXBUILD ?= sphinx-build
|
8
|
+
SOURCEDIR = source
|
9
|
+
BUILDDIR = build
|
10
|
+
|
11
|
+
# Put it first so that "make" without argument is like "make help".
|
12
|
+
help:
|
13
|
+
@$(SPHINXBUILD) -M help "$(SOURCEDIR)" "$(BUILDDIR)" $(SPHINXOPTS) $(O)
|
14
|
+
|
15
|
+
.PHONY: help Makefile
|
16
|
+
|
17
|
+
# Catch-all target: route all unknown targets to Sphinx using the new
|
18
|
+
# "make mode" option. $(O) is meant as a shortcut for $(SPHINXOPTS).
|
19
|
+
%: Makefile
|
20
|
+
@$(SPHINXBUILD) -M $@ "$(SOURCEDIR)" "$(BUILDDIR)" $(SPHINXOPTS) $(O)
|
gsmap-1.60/docs/make.bat
ADDED
@@ -0,0 +1,35 @@
|
|
1
|
+
@ECHO OFF
|
2
|
+
|
3
|
+
pushd %~dp0
|
4
|
+
|
5
|
+
REM Command file for Sphinx documentation
|
6
|
+
|
7
|
+
if "%SPHINXBUILD%" == "" (
|
8
|
+
set SPHINXBUILD=sphinx-build
|
9
|
+
)
|
10
|
+
set SOURCEDIR=source
|
11
|
+
set BUILDDIR=build
|
12
|
+
|
13
|
+
%SPHINXBUILD% >NUL 2>NUL
|
14
|
+
if errorlevel 9009 (
|
15
|
+
echo.
|
16
|
+
echo.The 'sphinx-build' command was not found. Make sure you have Sphinx
|
17
|
+
echo.installed, then set the SPHINXBUILD environment variable to point
|
18
|
+
echo.to the full path of the 'sphinx-build' executable. Alternatively you
|
19
|
+
echo.may add the Sphinx directory to PATH.
|
20
|
+
echo.
|
21
|
+
echo.If you don't have Sphinx installed, grab it from
|
22
|
+
echo.https://www.sphinx-doc.org/
|
23
|
+
exit /b 1
|
24
|
+
)
|
25
|
+
|
26
|
+
if "%1" == "" goto help
|
27
|
+
|
28
|
+
%SPHINXBUILD% -M %1 %SOURCEDIR% %BUILDDIR% %SPHINXOPTS% %O%
|
29
|
+
goto end
|
30
|
+
|
31
|
+
:help
|
32
|
+
%SPHINXBUILD% -M help %SOURCEDIR% %BUILDDIR% %SPHINXOPTS% %O%
|
33
|
+
|
34
|
+
:end
|
35
|
+
popd
|