consenrich 0.4.4b1__tar.gz → 0.4.4b2__tar.gz

{consenrich-0.4.4b1/src/consenrich.egg-info → consenrich-0.4.4b2}/PKG-INFO

@@ -1,6 +1,6 @@
 Metadata-Version: 2.4
 Name: consenrich
-Version: 0.4.4b1
+Version: 0.4.4b2
 Summary: Genome-wide estimation of signals hidden in noisy multi-sample HTS datasets
 Author-email: "Nolan H. Hamilton" <nolan.hamilton@unc.edu>
 Requires-Python: >=3.11
@@ -34,14 +34,20 @@ Dynamic: requires-python
 
 # Consenrich
 
-Consenrich is an adaptive linear filter for genome-wide estimation of signals hidden in
-noisy multi-sample HTS datasets. Consenrich supports a variety of functional genomics assays including ATAC-seq, DNase-seq, ChIP-seq, CUT&RUN, etc.
+Consenrich is an adaptive linear state estimator that yields genome-wide, uncertainty-calibrated signal tracks from noisy multi-sample HTS data.
 
-![Simplified Schematic of Consenrich.](docs/images/noise.png)
+<p align="center">
+  <img src="docs/images/noise.png" alt="Simplified Schematic of Consenrich." width="600">
+</p>
+
+
+Special emphasis is placed on computational efficiency, model interpretability, and practical utility for downstream tasks that require well-resolved genome-wide signal estimates and uncertainty quantification across samples, such as:
+
+* Consensus detection of open chromatin regions, TF footprints, nucleosome occupancy, histone modification
+* Candidate selection and boundary refinement for differential analyses, fine-mapping, reporter assays, etc.
 
 [**See the Documentation**](https://nolan-h-hamilton.github.io/Consenrich/) for usage examples, installation details, configuration options, and an API reference.
 
----
 
 ## Manuscript Preprint and Citation
 

consenrich-0.4.4b2/README.md

@@ -0,0 +1,31 @@
+# Consenrich
+
+Consenrich is an adaptive linear state estimator that yields genome-wide, uncertainty-calibrated signal tracks from noisy multi-sample HTS data.
+
+<p align="center">
+  <img src="docs/images/noise.png" alt="Simplified Schematic of Consenrich." width="600">
+</p>
+
+
+Special emphasis is placed on computational efficiency, model interpretability, and practical utility for downstream tasks that require well-resolved genome-wide signal estimates and uncertainty quantification across samples, such as:
+
+* Consensus detection of open chromatin regions, TF footprints, nucleosome occupancy, histone modification
+* Candidate selection and boundary refinement for differential analyses, fine-mapping, reporter assays, etc.
+
+[**See the Documentation**](https://nolan-h-hamilton.github.io/Consenrich/) for usage examples, installation details, configuration options, and an API reference.
+
+
+## Manuscript Preprint and Citation
+
+**BibTeX Citation**
+
+```bibtex
+@article {Hamilton2025,
+	author = {Hamilton, Nolan H and Huang, Yu-Chen E and McMichael, Benjamin D and Love, Michael I and Furey, Terrence S},
+	title = {Genome-Wide Uncertainty-Moderated Extraction of Signal Annotations from Multi-Sample Functional Genomics Data},
+	year = {2025},
+	doi = {10.1101/2025.02.05.636702},
+	publisher = {Cold Spring Harbor Laboratory},
+	journal = {bioRxiv}
+}
+```

{consenrich-0.4.4b1 → consenrich-0.4.4b2}/pyproject.toml

@@ -10,7 +10,7 @@ build-backend = "setuptools.build_meta"
 
 [project]
 name = "consenrich"
-version = "0.4.4b1"
+version = "0.4.4b2"
 description = "Genome-wide estimation of signals hidden in noisy multi-sample HTS datasets"
 authors = [{ name="Nolan H. Hamilton", email="nolan.hamilton@unc.edu" }]
 readme = "README.md"

{consenrich-0.4.4b1 → consenrich-0.4.4b2}/setup.py

@@ -36,7 +36,7 @@ extensions = [
 
 setup(
     name="consenrich",
-    version="0.4.4b1",
+    version="0.4.4b2",
     packages=find_packages(where="src"),
     include_package_data=True,
     package_dir={"": "src"},