FedGWAS 0.3.1__tar.gz

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (185) hide show
  1. fedgwas-0.3.1/.flwr/.gitignore +1 -0
  2. fedgwas-0.3.1/.github/workflows/deploy-docs.yml +61 -0
  3. fedgwas-0.3.1/.github/workflows/publish-pypi.yml +57 -0
  4. fedgwas-0.3.1/.gitignore +139 -0
  5. fedgwas-0.3.1/CURRENT_VERSION.md +639 -0
  6. fedgwas-0.3.1/LICENSE +21 -0
  7. fedgwas-0.3.1/PKG-INFO +276 -0
  8. fedgwas-0.3.1/README.md +235 -0
  9. fedgwas-0.3.1/RELEASE.md +141 -0
  10. fedgwas-0.3.1/cluster_deployment/README.md +90 -0
  11. fedgwas-0.3.1/cluster_deployment/docs/CLUSTER_USER_GUIDE.md +631 -0
  12. fedgwas-0.3.1/cluster_deployment/scripts/check-cluster-clock-skew.sh +66 -0
  13. fedgwas-0.3.1/cluster_deployment/scripts/cluster-config-template.sh +8 -0
  14. fedgwas-0.3.1/cluster_deployment/scripts/cluster-diagnose.sh +100 -0
  15. fedgwas-0.3.1/cluster_deployment/scripts/cluster-run-app.sh +143 -0
  16. fedgwas-0.3.1/cluster_deployment/scripts/cluster-start-client.sh +141 -0
  17. fedgwas-0.3.1/cluster_deployment/scripts/cluster-start-server.sh +44 -0
  18. fedgwas-0.3.1/cluster_deployment/scripts/cluster-status.sh +16 -0
  19. fedgwas-0.3.1/cluster_deployment/scripts/cluster-stop-all.sh +15 -0
  20. fedgwas-0.3.1/cluster_deployment/scripts/cluster-verify-data.sh +91 -0
  21. fedgwas-0.3.1/cluster_deployment/scripts/download-flwr-wheels.sh +22 -0
  22. fedgwas-0.3.1/cluster_deployment/scripts/setup-cluster-node.sh +189 -0
  23. fedgwas-0.3.1/configs/config.yaml +36 -0
  24. fedgwas-0.3.1/configs/config_template.yaml +36 -0
  25. fedgwas-0.3.1/docs/experiments/overview.md +70 -0
  26. fedgwas-0.3.1/docs/experiments/runner.md +76 -0
  27. fedgwas-0.3.1/docs/getting-started/configuration.md +111 -0
  28. fedgwas-0.3.1/docs/getting-started/deployment.md +92 -0
  29. fedgwas-0.3.1/docs/getting-started/installation.md +82 -0
  30. fedgwas-0.3.1/docs/getting-started/simulation.md +68 -0
  31. fedgwas-0.3.1/docs/images/Architecture.png +0 -0
  32. fedgwas-0.3.1/docs/intro.md +42 -0
  33. fedgwas-0.3.1/docs/modules/association.md +35 -0
  34. fedgwas-0.3.1/docs/modules/client.md +44 -0
  35. fedgwas-0.3.1/docs/modules/kinship.md +36 -0
  36. fedgwas-0.3.1/docs/modules/quality-control.md +44 -0
  37. fedgwas-0.3.1/docs/modules/server.md +49 -0
  38. fedgwas-0.3.1/docs/pipeline/architecture.md +75 -0
  39. fedgwas-0.3.1/docs/pipeline/privacy-masking.md +39 -0
  40. fedgwas-0.3.1/docs/pipeline/workflow.md +55 -0
  41. fedgwas-0.3.1/docs/troubleshooting.md +67 -0
  42. fedgwas-0.3.1/experiments/README.md +198 -0
  43. fedgwas-0.3.1/experiments/correctness/tiny_even/README.md +90 -0
  44. fedgwas-0.3.1/experiments/correctness/tiny_even/config.yaml +63 -0
  45. fedgwas-0.3.1/experiments/correctness/tiny_even/configs/center_1/config.yaml +43 -0
  46. fedgwas-0.3.1/experiments/correctness/tiny_even/configs/center_2/config.yaml +43 -0
  47. fedgwas-0.3.1/experiments/correctness/tiny_even/configs/server/config.yaml +3 -0
  48. fedgwas-0.3.1/experiments/performance/medium_even/README.md +87 -0
  49. fedgwas-0.3.1/experiments/performance/medium_even/config.yaml +60 -0
  50. fedgwas-0.3.1/experiments/performance/medium_even/configs/center_1/config.yaml +41 -0
  51. fedgwas-0.3.1/experiments/performance/medium_even/configs/center_2/config.yaml +41 -0
  52. fedgwas-0.3.1/experiments/performance/medium_even/configs/server/config.yaml +3 -0
  53. fedgwas-0.3.1/experiments/performance/scales.yaml +27 -0
  54. fedgwas-0.3.1/experiments/performance/small_even/README.md +57 -0
  55. fedgwas-0.3.1/experiments/performance/small_even/config.yaml +60 -0
  56. fedgwas-0.3.1/experiments/performance/small_even/configs/center_1/config.yaml +43 -0
  57. fedgwas-0.3.1/experiments/performance/small_even/configs/center_2/config.yaml +43 -0
  58. fedgwas-0.3.1/experiments/performance/small_even/configs/server/config.yaml +3 -0
  59. fedgwas-0.3.1/experiments/real_world/1000genomes/EXPERIMENT_STATUS.md +68 -0
  60. fedgwas-0.3.1/experiments/real_world/1000genomes/README.md +245 -0
  61. fedgwas-0.3.1/experiments/real_world/1000genomes/config.yaml +23 -0
  62. fedgwas-0.3.1/experiments/real_world/1000genomes/configs/center_1/config.yaml +41 -0
  63. fedgwas-0.3.1/experiments/real_world/1000genomes/configs/center_2/config.yaml +41 -0
  64. fedgwas-0.3.1/experiments/real_world/1000genomes/configs/server/config.yaml +3 -0
  65. fedgwas-0.3.1/experiments/real_world/1000genomes/download_subset.sh +95 -0
  66. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/PLOT_COMPARISON.md +73 -0
  67. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/README.md +81 -0
  68. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/VISUALIZATION_GUIDE.md +73 -0
  69. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/baseline_validation_report.md +117 -0
  70. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/king_correlation.png +0 -0
  71. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/lr_correlation.png +0 -0
  72. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/manhattan_baseline.png +0 -0
  73. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/manhattan_comparison.png +0 -0
  74. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/manhattan_federated.png +0 -0
  75. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/qq_baseline.png +0 -0
  76. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/figures/qq_federated.png +0 -0
  77. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/manuscript_sections.md +39 -0
  78. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/summary.json +31 -0
  79. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/coverage_table.md +9 -0
  80. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/coverage_table.tex +16 -0
  81. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/filtering_table.md +9 -0
  82. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/filtering_table.tex +15 -0
  83. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/king_table.md +9 -0
  84. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/lr_table.md +6 -0
  85. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/qc_table.md +9 -0
  86. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/tables/qc_table.tex +12 -0
  87. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/threshold_analysis/RECOMMENDATIONS.md +60 -0
  88. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/threshold_analysis/threshold_sensitivity_5e-8.png +0 -0
  89. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/threshold_analysis/threshold_sensitivity_results.csv +41 -0
  90. fedgwas-0.3.1/experiments/real_world/1000genomes/manuscript/threshold_analysis/threshold_sensitivity_summary.md +27 -0
  91. fedgwas-0.3.1/experiments/real_world/1000genomes/run_evaluation.sh +60 -0
  92. fedgwas-0.3.1/experiments/real_world/1000genomes/run_experiment.sh +31 -0
  93. fedgwas-0.3.1/experiments/real_world/README.md +231 -0
  94. fedgwas-0.3.1/experiments/real_world/phenotype_generation/README.md +124 -0
  95. fedgwas-0.3.1/experiments/real_world/phenotype_generation/__init__.py +19 -0
  96. fedgwas-0.3.1/experiments/real_world/phenotype_generation/generate_phenotypes.py +312 -0
  97. fedgwas-0.3.1/experiments/real_world/phenotype_generation/models.py +360 -0
  98. fedgwas-0.3.1/experiments/tools/analyze_threshold_sensitivity.py +288 -0
  99. fedgwas-0.3.1/experiments/tools/apply_run_retention.py +60 -0
  100. fedgwas-0.3.1/experiments/tools/collect_run_metrics.py +195 -0
  101. fedgwas-0.3.1/experiments/tools/evaluation/README.md +79 -0
  102. fedgwas-0.3.1/experiments/tools/evaluation/collect_real_world_results.py +233 -0
  103. fedgwas-0.3.1/experiments/tools/evaluation/evaluate_all.py +200 -0
  104. fedgwas-0.3.1/experiments/tools/evaluation/king/analyze_king_partial_debug.py +401 -0
  105. fedgwas-0.3.1/experiments/tools/evaluation/king/compare_king_from_accumulator.py +314 -0
  106. fedgwas-0.3.1/experiments/tools/evaluation/lr/lr_evaluator.py +813 -0
  107. fedgwas-0.3.1/experiments/tools/evaluation/lr/sf_gwas_comparison.py +411 -0
  108. fedgwas-0.3.1/experiments/tools/evaluation/metrics_collector.py +429 -0
  109. fedgwas-0.3.1/experiments/tools/evaluation/qc/investigate_mismatches.py +315 -0
  110. fedgwas-0.3.1/experiments/tools/evaluation/qc/qc_evaluator.py +266 -0
  111. fedgwas-0.3.1/experiments/tools/filter_multiallelic.py +400 -0
  112. fedgwas-0.3.1/experiments/tools/fix_snp_ids.py +60 -0
  113. fedgwas-0.3.1/experiments/tools/generate_baseline.py +566 -0
  114. fedgwas-0.3.1/experiments/tools/generate_manuscript_materials.py +1455 -0
  115. fedgwas-0.3.1/experiments/tools/setup_real_world_experiment.py +301 -0
  116. fedgwas-0.3.1/experiments/tools/summarize_scalability_table.py +112 -0
  117. fedgwas-0.3.1/pipeline/__init__.py +0 -0
  118. fedgwas-0.3.1/pipeline/client_app.py +1302 -0
  119. fedgwas-0.3.1/pipeline/clients/__init__.py +3 -0
  120. fedgwas-0.3.1/pipeline/clients/base_client.py +737 -0
  121. fedgwas-0.3.1/pipeline/clients/c2c_payloads.py +38 -0
  122. fedgwas-0.3.1/pipeline/clients/client_qc_aggregator.py +184 -0
  123. fedgwas-0.3.1/pipeline/clients/client_to_client.py +152 -0
  124. fedgwas-0.3.1/pipeline/clients/config.yaml +26 -0
  125. fedgwas-0.3.1/pipeline/clients/data_loder.py +189 -0
  126. fedgwas-0.3.1/pipeline/clients/flwr_config.py +29 -0
  127. fedgwas-0.3.1/pipeline/clients/iterative_king.py +944 -0
  128. fedgwas-0.3.1/pipeline/clients/iterative_lr.py +472 -0
  129. fedgwas-0.3.1/pipeline/clients/local_qc.py +275 -0
  130. fedgwas-0.3.1/pipeline/clients/logger_manager.py +106 -0
  131. fedgwas-0.3.1/pipeline/clients/lr_privacy.py +61 -0
  132. fedgwas-0.3.1/pipeline/clients/seed_sync.py +203 -0
  133. fedgwas-0.3.1/pipeline/server/aggregator_king.py +456 -0
  134. fedgwas-0.3.1/pipeline/server/aggregator_lr.py +454 -0
  135. fedgwas-0.3.1/pipeline/server/prg_masking.py +197 -0
  136. fedgwas-0.3.1/pipeline/server/strategy_strict.py +513 -0
  137. fedgwas-0.3.1/pipeline/server_app.py +168 -0
  138. fedgwas-0.3.1/pipeline/utils/client_data_loader.py +7 -0
  139. fedgwas-0.3.1/pipeline/utils/monitoring_config.py +104 -0
  140. fedgwas-0.3.1/pipeline/utils/performance/__init__.py +17 -0
  141. fedgwas-0.3.1/pipeline/utils/performance/monitoring_runtime.py +215 -0
  142. fedgwas-0.3.1/pipeline/utils/performance/network_monitor.py +368 -0
  143. fedgwas-0.3.1/pipeline/utils/performance/performance_monitoring.py +526 -0
  144. fedgwas-0.3.1/pipeline/utils/retention_config.py +124 -0
  145. fedgwas-0.3.1/pipeline/utils/run_retention.py +272 -0
  146. fedgwas-0.3.1/plink/plink_linux/LICENSE +674 -0
  147. fedgwas-0.3.1/plink/plink_linux/plink +0 -0
  148. fedgwas-0.3.1/plink/plink_linux/plink2 +0 -0
  149. fedgwas-0.3.1/plink/plink_linux/prettify +0 -0
  150. fedgwas-0.3.1/plink/plink_linux/toy.map +2 -0
  151. fedgwas-0.3.1/plink/plink_linux/toy.ped +2 -0
  152. fedgwas-0.3.1/plink/plink_mac/LICENSE +674 -0
  153. fedgwas-0.3.1/plink/plink_mac/plink +0 -0
  154. fedgwas-0.3.1/plink/plink_mac/plink2 +0 -0
  155. fedgwas-0.3.1/plink/plink_mac/prettify +0 -0
  156. fedgwas-0.3.1/plink/plink_mac/toy.map +2 -0
  157. fedgwas-0.3.1/plink/plink_mac/toy.ped +2 -0
  158. fedgwas-0.3.1/plink/plink_win/LICENSE +674 -0
  159. fedgwas-0.3.1/plink/plink_win/plink.exe +0 -0
  160. fedgwas-0.3.1/plink/plink_win/prettify.exe +0 -0
  161. fedgwas-0.3.1/plink/plink_win/toy.map +2 -0
  162. fedgwas-0.3.1/plink/plink_win/toy.ped +2 -0
  163. fedgwas-0.3.1/pyproject.toml +89 -0
  164. fedgwas-0.3.1/tests/test_association.py +47 -0
  165. fedgwas-0.3.1/tests/test_king_federated_unit.py +216 -0
  166. fedgwas-0.3.1/tests/test_kinship.py +86 -0
  167. fedgwas-0.3.1/tests/test_monitoring_config.py +18 -0
  168. fedgwas-0.3.1/tests/test_monitoring_runtime.py +31 -0
  169. fedgwas-0.3.1/tests/test_performance_monitor_append.py +32 -0
  170. fedgwas-0.3.1/tests/test_prg_masking.py +242 -0
  171. fedgwas-0.3.1/tests/test_qc.py +47 -0
  172. fedgwas-0.3.1/tests/test_quality_control.py +87 -0
  173. fedgwas-0.3.1/tests/test_reader.py +36 -0
  174. fedgwas-0.3.1/tests/test_run_retention.py +46 -0
  175. fedgwas-0.3.1/tests/test_synthetic_data.py +455 -0
  176. fedgwas-0.3.1/tests/test_visualization.py +57 -0
  177. fedgwas-0.3.1/tests/test_visualization_comprehensive.py +395 -0
  178. fedgwas-0.3.1/uv.lock +2266 -0
  179. fedgwas-0.3.1/website/docusaurus.config.js +108 -0
  180. fedgwas-0.3.1/website/package-lock.json +17506 -0
  181. fedgwas-0.3.1/website/package.json +26 -0
  182. fedgwas-0.3.1/website/sidebars.js +48 -0
  183. fedgwas-0.3.1/website/src/css/custom.css +62 -0
  184. fedgwas-0.3.1/website/src/pages/index.js +155 -0
  185. fedgwas-0.3.1/website/src/pages/index.module.css +221 -0
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+ .credentials
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+ name: Deploy documentation
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+ on:
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+ push:
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+ tags:
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+ - '*'
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+ workflow_dispatch:
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+
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+ permissions:
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+ contents: read
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+ pages: write
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+ id-token: write
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+ concurrency:
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+ group: github-pages
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+ cancel-in-progress: false
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+
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+ jobs:
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+ build:
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+ name: Build Docusaurus site
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+ runs-on: ubuntu-latest
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+
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+ steps:
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+ - name: Checkout
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+ uses: actions/checkout@v4
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+
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+ - name: Set up Node.js
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+ uses: actions/setup-node@v4
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+ with:
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+ node-version: 20
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+ cache: npm
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+ cache-dependency-path: website/package-lock.json
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+
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+ - name: Install dependencies
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+ working-directory: website
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+ run: npm ci
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+
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+ - name: Build documentation
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+ working-directory: website
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+ run: npm run build
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+
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+ - name: Configure GitHub Pages
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+ uses: actions/configure-pages@v5
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+
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+ - name: Upload Pages artifact
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+ uses: actions/upload-pages-artifact@v3
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+ with:
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+ path: website/build
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+
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+ deploy:
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+ name: Deploy to GitHub Pages
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+ needs: build
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+ runs-on: ubuntu-latest
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+ environment:
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+ name: github-pages
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+ url: ${{ steps.deployment.outputs.page_url }}
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+
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+ steps:
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+ - name: Deploy
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+ id: deployment
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+ uses: actions/deploy-pages@v4
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+ name: Publish Python package
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+
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+ on:
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+ release:
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+ types: [published]
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+
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+ permissions:
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+ contents: read
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+
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+ jobs:
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+ build:
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+ name: Build distribution
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+ runs-on: ubuntu-latest
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+
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+ steps:
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+ - name: Checkout
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+ uses: actions/checkout@v4
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+
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+ - name: Set up Python
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+ uses: actions/setup-python@v5
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+ with:
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+ python-version: "3.11"
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+
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+ - name: Install build tools
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+ run: python -m pip install --upgrade build twine
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+
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+ - name: Build distributions
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+ run: python -m build
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+
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+ - name: Check distributions
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+ run: python -m twine check dist/*
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+
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+ - name: Upload distributions
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+ uses: actions/upload-artifact@v4
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+ with:
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+ name: python-package-distributions
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+ path: dist/
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+
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+ publish:
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+ name: Publish to PyPI
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+ needs: build
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+ runs-on: ubuntu-latest
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+ environment:
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+ name: pypi
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+ url: https://pypi.org/project/FedGWAS/
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+ permissions:
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+ id-token: write
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+
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+ steps:
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+ - name: Download distributions
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+ uses: actions/download-artifact@v4
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+ with:
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+ name: python-package-distributions
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+ path: dist/
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+
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+ - name: Publish distributions to PyPI
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+ uses: pypa/gh-action-pypi-publish@release/v1
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+ .venv
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+ dist/
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+ sdist/
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+ **/__pycache__/
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+ .pytest_cache/
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+ *.pyc
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+ .mypy_cache/
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+ website/.docusaurus/
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+
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+ # Data
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+ user_data/
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+
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+ # Logs
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+ logs
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+ npm-debug.log*
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+ yarn-debug.log*
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+ yarn-error.log*
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+ dev-debug.log
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+
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+ # Dependency directories
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+ website/node_modules/
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+ website/build/
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+
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+ # Environment variables
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+ .env
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+
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+ # Editor directories and files
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+ .idea
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+ .vscode
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+ *.suo
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+ *.ntvs*
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+ *.njsproj
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+ *.sln
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+ *.sw?
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+
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+ # OS specific
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+ .DS_Store
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+ **/.DS_Store
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+
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+ # Legacy/archived directories
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+ archived/
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+ bin/
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+ centers/
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+ data/
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+
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+ # Unused / local-only pipeline paths
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+ pipeline/exerpiements.md
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+ pipeline/experiments.md
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+ pipeline/simulation/
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+ pipeline/visualization_archived/
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+ pipeline/server/strategy.py
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+ pipeline/server/strategy_new.py
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+ pipeline/server/aggregator_qc.py
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+ pipeline/utils/bloom_filter.py
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+
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+ # Redundant/outdated documentation
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+ Readme_pipeline.md
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+ EXPERIMENT_RUNNER_README.md
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+ prd/
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+ .pre-commit-config.yaml
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+ !cluster_deployment/docs/
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+ !cluster_deployment/docs/**
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+
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+ # Docker (local workflow only; cluster deployment is under cluster_deployment/)
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+ docker/
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+ .dockerignore
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+
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+ # Performance manuscript drafts (local only; configs stay in repo)
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+ experiments/performance/README.md
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+ experiments/performance/appendix_sections.md
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+ experiments/performance/appendix_table.md
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+ experiments/performance/appendix_table.tex
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+ experiments/performance/manuscript_sections.md
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+
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+ # Local notes, reports, and archives (not shipped)
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+ ISSUES_REPORT.md
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+ ISSUES_REPORT_UPDATED.md
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+ plan.md
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+ experiments.docx
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+ InfoSummit_kinship.pdf
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+ mkdocs.yml
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+ pipeline.pdf
83
+ pipeline.zip
84
+ plink.zip
85
+ results/
86
+
87
+ # Experiment run outputs and synthetic data artifacts
88
+ experiments/**/results/
89
+ experiments/**/results_*/
90
+ experiments/*/*/results/
91
+ experiments/**/data/**/*.bed
92
+ experiments/**/data/**/*.bim
93
+ experiments/**/data/**/*.fam
94
+ experiments/**/data/**/*.log
95
+ experiments/**/data/**/*.kin0
96
+ experiments/**/data/**/*.assoc*
97
+ experiments/**/data/**/*.genome
98
+ experiments/**/data/**/*.hwe
99
+ experiments/**/data/**/*.imiss
100
+ experiments/**/data/**/*.lmiss
101
+ experiments/**/data/**/*.frq
102
+ experiments/**/intermediate/
103
+ **/__pycache__/
104
+
105
+ # Task / cluster bundles
106
+ fedgwas-cluster.tar.gz
107
+ cluster_deployment/wheels/
108
+
109
+ # Log files
110
+ *.log
111
+ **/*.log
112
+
113
+ # PLINK output files
114
+ *.bed
115
+ *.bim
116
+ *.fam
117
+ *.kin0
118
+ *.assoc*
119
+ *.genome
120
+ *.hwe
121
+ *.imiss
122
+ *.lmiss
123
+ *.frq
124
+
125
+ # Large data files (duplicate patterns for safety)
126
+ *.bed
127
+ *.bim
128
+ *.fam
129
+
130
+ # claude
131
+ .claude/
132
+ .venv/
133
+ claude.md
134
+ .windsurfrules
135
+ README-task-manager.md
136
+ .env.example
137
+ /scripts/
138
+ .cursor/*
139
+ .test_scenario_a.py