viral_seq 1.8.0 → 1.8.1.1

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data/README.md CHANGED
@@ -187,7 +187,12 @@ qc_seqhash.sdrm_hiv_pr(cut_off)
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  ## Updates
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- ### Version-1.8.0.pre-04052024
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+
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+ ### Version-1.8.1-06042024
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+
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+ 1. Fixed a bug that causes `tcs_sdrm` pipeline to crash.
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+
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+ ### Version-1.8.0-04052024
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  1. Use `muscle-v3.8.1` as default aligner because of the compatibility issues with `muscle-v5` on some platforms.
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  2. Adjust the end-join model for short insert (insert size less than read length substracted by adaptor size)
@@ -49,7 +49,10 @@ module ViralSeq
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  return recency
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  end #end of .define
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-
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+ # function for predict Days Post Infection
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+ # @params pi_rt [Float] average pairwise diversity at RT region
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+ # @params pi_viv3 [Float] average pairwise diversity at V1V3 region
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+ # @return [Array] Array of [DPI, lwr, upr] for DPI prediction as [Numerics]
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  def self.dpi(pi_rt, pi_v1v3)
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  if pi_rt.is_a? Numeric and pi_v1v3.is_a? Numeric
@@ -70,9 +73,9 @@ module ViralSeq
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  path = File.join( ViralSeq.root, "viral_seq", "util", "recency_model", model_file)
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  data_str = `Rscript -e 'fit = readRDS("#{path}"); test = data.frame(#{var} = #{pi}); pre= predict(fit, test, interval = "prediction", level = 0.9); cat(pre)'`
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  dpi_array = data_str.split("\s")
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- dpi = dpi_array[0].to_f
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- lwr = dpi_array[1].to_f
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- upr = dpi_array[2].to_f
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+ dpi = dpi_array[0].to_f.round(1)
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+ lwr = dpi_array[1].to_f.round(1)
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+ upr = dpi_array[2].to_f.round(1)
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  if lwr < 0
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  return [dpi, 0.0, upr]
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  else
@@ -80,6 +83,11 @@ module ViralSeq
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  end
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  end # end of .dpi
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+ # given `recency` and `dpi` predict if possible dual infection exists
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+ # @params recency [String] Recency from ViralSeq::Recency.define() function
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+ # @params dpi [Array] DPI array from ViralSeq::Recency.dpi() function
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+ # @return [String] "Yes", "No", or "insufficient data"
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+
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  def self.possible_dual_infection(recency, dpi)
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  if ["recent", "chronic", "indeterminant"].include? recency and dpi[0].is_a? Numeric
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  if recency == "indeterminant" and dpi[0] > 730
@@ -92,7 +100,7 @@ module ViralSeq
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  end
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  end
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- end
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+ end # end of .possible_dual_infection
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  end
@@ -141,8 +141,8 @@ module ViralSeq
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  },
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  {
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- text: log[:dpi].round(1).to_s +
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- " (" + log[:dpi_lwr].round(1).to_s + "-" + log[:dpi_upr].round(1).to_s + ") Days",
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+ text: log[:dpi].to_s +
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+ " (" + log[:dpi_lwr].to_s + "-" + log[:dpi_upr].to_s + ") Days",
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  styles: [:bold],
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  size: 16,
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  color: recency_color[log[:recency]]
@@ -2,6 +2,6 @@
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  # version info and histroy
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  module ViralSeq
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- VERSION = "1.8.0"
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- TCS_VERSION = "2.6.0"
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+ VERSION = "1.8.1.1"
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+ TCS_VERSION = "2.6.1"
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  end
metadata CHANGED
@@ -1,7 +1,7 @@
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  --- !ruby/object:Gem::Specification
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  name: viral_seq
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  version: !ruby/object:Gem::Version
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- version: 1.8.0
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+ version: 1.8.1.1
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  platform: ruby
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  authors:
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  - Shuntai Zhou
@@ -9,7 +9,7 @@ authors:
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  autorequire:
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  bindir: bin
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  cert_chain: []
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- date: 2024-05-09 00:00:00.000000000 Z
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+ date: 2024-06-04 00:00:00.000000000 Z
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  dependencies:
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  - !ruby/object:Gem::Dependency
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  name: bundler
@@ -222,7 +222,7 @@ required_rubygems_version: !ruby/object:Gem::Requirement
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  version: 1.3.6
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  requirements:
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  - R required for some functions
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- rubygems_version: 3.5.9
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+ rubygems_version: 3.5.10
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  signing_key:
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  specification_version: 4
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  summary: A Ruby Gem containing bioinformatics tools for processing viral NGS data.